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Compound Amino Acid Injection for Children (18AA-Ⅰ)

Function and Efficacy

Amino acids are the basic units that make up human proteins and enzymes, and are the raw materials for synthesizing hormones. They participate in human metabolism and various physiological functions, and play a special role in life. Amino acids have different metabolic effects in infants and adults. The activity of phenylalanine hydroxylase in infants is low, which can easily lead to hyperphenylalaninemia. Because of the low activity of cystathionase, hypermethioninemia is easy to occur. The synthesis rate of histidine is slow, which can easily lead to hypohistidinemia. Therefore, the dosage of phenylalanine, methylthiothionine, and glycine should be reduced for amino acid infusion for infants and young children, and the dosage of cysteine, tyrosine, and histidine should be increased, so that the plasma amino acid spectrum can remain normal. This product adapts to the metabolic characteristics of infants and young children, reduces the dosage of phenylalanine, methylthiothionine, and glycine, increases the dosage of cysteine and histidine, and meets the nutritional needs of children.

Ingredients

The product is a compound preparation, and its components are as follows: Each 1000ml contains: Isoleucine (C6H13NO2) 3.1g Lysine acetate (C6H14N2O2·C2H4O2) 7.9g Phenylalanine (C9H11NO2) 2.7g Tryptophan (C11H12N2O2) 1.4g Histidine (C6H9N3O2) 2.1g Proline (C5H9NO2) 5.6g Serine (C3H7NO3) 3.8g Glutamic acid (C5H9NO4) 7.1g N-acetyl-L-tyrosine (C11H13NO4) 0.6g Leucine (C6H13NO2) 7.0g Methionine (C15H11NO2S) 1.3g Threonine

Name Description Content CAS NO. Manufacturer
L-IsoleucineIngredients

Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions.

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73-32-5 20
L-Lysine acetateIngredients

Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions.

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57282-49-2 13
L-PhenylalanineIngredients

The activity of phenylalanine hydroxylase in infants and young children is low, and they are prone to hyperphenylalaninemia, so the dosage should be reduced.

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673-31-4 4
L-HistidineIngredients

The synthesis rate of histidine is slow, which can easily lead to hypohistidinemia, so the dosage needs to be increased.

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71-00-1 20
DL-ProlineIngredients

Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions.

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609-36-9 9
DL-SerineIngredients

Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions.

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302-84-1 10
L-Glutamic acidIngredients

Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions.

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56-86-0 18
N-Acetyl-L-tyrosineIngredients

To meet the nutritional needs of children, increase the amount of tyrosine to adapt to the metabolic characteristics of infants and young children.

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537-55-3 8
N-CARBOBENZOXY-DL-LEUCINEIngredients

Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions.

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3588-60-1 14
DL-MethionineIngredients

Because the activity of cystathionase is low, hypermethioninemia is likely to occur, so the dosage should be reduced.

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59-51-8 10

Appearance

This product is a colorless or slightly yellow clear liquid.

Indication

1. Suitable for children who cannot take food through the gastrointestinal tract due to digestive system diseases. 2. Suitable for children with hypoproteinemia caused by various diseases. 3. Suitable for children with severe trauma, burns, sepsis and other nitrogen imbalances in the body. 4. Suitable for refractory diarrhea and malabsorption syndrome. 5. Suitable for parenteral nutrition of premature infants and low-weight infants.

Usage and Dosage

1 When this product is used for a long time through the central vein, it should be used in combination with hypertonic glucose (or glucose and fat emulsion), electrolytes, vitamins, trace elements, etc., in order to achieve the purpose of nutritional support. 2 When this product is used through the peripheral vein, it can be diluted with 10% glucose injection and slowly dripped. 3 Infusion rate: When full nutrition is infused through the peripheral vein, the full daily dose should be diluted and dripped evenly for no less than 16 hours. For partial intravenous nutrition infusion and central vein infusion, follow the doctor's advice. 4 The infusion volume should be determined according to the child's age, weight, condition, etc. The general dosage is 15ml/kg/day of amino acids at the beginning (equivalent to about 1g of amino acids), and then increased to 3

Adverse Reactions

When this product is infused too quickly, it may cause increased heart rate, gastrointestinal reactions, and fever.

Precautions

1. Children with liver and kidney damage. 2. Children with amino acid metabolism disorders.

Drug Interactions

Not yet clear.

Storage

Store in a cool dark place. Valid for two years.

Packaging Specification

250 ml: 16.85 g (total amino acids)

Manufacturer

Cisen Pharmaceutical Co., Ltd.

  • Founded in:

    1998-11-06
  • Address:

    Tongji Science and Technology Industrial Park, Jining High-tech Zone
  • Tax NO.:

    91370800706117999P
  • Registered Funds:

    452,754,129 yuan
  • Website:

  • Email:

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