Compound Tetrazine Reserpine Tablets

Pharmacological action: Reserpine and hydralazine hydrochloride in this product are basic antihypertensive drugs. Reserpine is an anti-noradrenergic antihypertensive drug that can deplete norepinephrine in peripheral sympathetic nerve endings, deplete catecholamines and 5-hydroxytryptamine storage in the heart, brain and other tissues to achieve antihypertensive, slow heart rate and inhibit the central nervous system. Reserpine can relieve anxiety, tension and headache in hypertensive patients. Hydrochlorothiazide and cyclopenthiazide are medium-acting diuretics that can reduce water and sodium retention, reduce blood volume, and reduce circulating blood volume, thus playing a hypotensive role. Promethazine hydrochloride has sedative, anti-anxiety and muscle relaxant effects. Vitamin B1 can improve the side effects of the above drugs, such as multiple neuritis, palpitations, chest tightness, and decreased appetite. Vitamin B6 can prevent neuritis, insomnia, restlessness, etc. that may be caused by hydralazine hydrochloride, and can also prevent the occurrence of side effects such as nausea and vomiting. Rutin can maintain vascular elasticity, enhance capillary resistance, promote cell proliferation and prevent blood cell aggregation, reduce vascular fragility, and reduce capillary permeability. Chloroquine phosphate can increase capillary permeability, which is not only beneficial to the antihypertensive effect of diuretic and antihypertensive drugs, but also can counteract the adverse effects of rutin on diuresis and antihypertensive effects by reducing capillary permeability. Toxicological studies: Animal experiments have teratogenic effects at 125 to 250 times the maximum clinical dose, and the commonly used clinical dose is 100 to 300 times, and the incidence of tumors increases.

This product is a compound preparation, and its components are: each tablet contains 0.03 mg of reserpine, 1 mg of hydralazine hydrochloride, 1.5 mg of hydrochlorothiazide, 0.025 mg of cyclopenthiazide, 2 mg of promethazine hydrochloride, 1 mg of vitamin B1, 1 mg of vitamin B6, 5 mg of rutin, 30 mg of potassium chloride, and 2.5 mg of chloroquine phosphate.

This product is a sugar-coated tablet, which appears yellow or light yellow after removing the coating.

Used for various types of hypertension.

Oral administration, 1-2 tablets at a time, 3 times a day.

1. Adverse reactions of reserpine include excessive sedation, inattention, anxiety, depression, arrhythmia, bradycardia, dizziness, nasal congestion, poor appetite, nausea and other digestive tract symptoms. 2. Hydralazine hydrochloride may cause headache, nausea, palpitations, tachycardia, rash, immune allergy, etc. 3. Diuretics should be used with caution to prevent water and electrolyte imbalance, hypokalemia, hyponatremia and hypochloremia.

1. It is contraindicated for those who are allergic to the ingredients of this product. 2. It is contraindicated for those with gastric and duodenal ulcers. 3. It is contraindicated for those with depression. 4. It is contraindicated for pregnant women and lactating women.

Precautions for children: This test has not been conducted and there are no reliable references. Precautions for pregnancy and lactation: Reserpine can pass through the placenta and cause increased respiratory secretions and nasal congestion in the fetus, and can enter breast milk and cause increased respiratory secretions, nasal congestion, cyanosis, hypothermia and loss of appetite in infants, so it is contraindicated for pregnant and lactating women. Precautions for the elderly: This test has not been conducted and there are no reliable references.

Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.

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Compound

24 months

Shanghai Kaibao Xinyi(Xinxiang)Pharmaceutical Co., Ltd.

• Founded in:

  1998-07-25

• Address:

  No. 399, Qinglong Road, Xinxiang Economic Development Zone

• Tax NO.:

  91410721706782120Y

• Registered Funds:

  82 million yuan

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