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Lisinopril Tablets

Function and Efficacy

This product is a third-generation angiotensin converting enzyme inhibitor, which can inhibit the activity of angiotensin converting enzyme, reduce the concentration of angiotensin II and aldosterone, increase plasma renin activity, lead to peripheral vasodilation and decreased vascular resistance, and thus produce a hypotensive effect. The hypotensive effect occurs within about 2 hours after oral administration, and the maximum hypotensive effect occurs about 4 to 6 hours after oral administration, which is consistent with the peak time of blood drug concentration (tmax). The hypotensive effect lasts for 24 hours, and there will be no blood pressure rebound after stopping the drug, and there is no significant change in heart rate after taking the drug.

Ingredients

The main ingredient of this product is: lisinopril.

Name Description Content CAS NO. Manufacturer
Lisinopril DihydrateIngredients

This product is a third-generation angiotensin converting enzyme inhibitor, which can inhibit the activity of angiotensin converting enzyme, reduce the concentration of angiotensin II and aldosterone, increase plasma renin activity, lead to peripheral vasodilation and decreased vascular resistance, and thus produce a hypotensive effect. The hypotensive effect occurs within about 2 hours after oral administration, and the maximum hypotensive effect occurs about 4 to 6 hours after oral administration, which is consistent with the peak time of blood drug concentration (tmax). The hypotensive effect lasts for 24 hours, and there will be no blood pressure rebound after stopping the drug, and there is no significant change in heart rate after taking the drug.

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83915-83-7 21

Appearance

This product is a slightly reddish tablet (10 mg) or slightly yellowish tablet (20 mg).

Indication

Used to treat essential hypertension.

Usage and Dosage

Oral: Once a day, the usual dose is 10-40 mg, the initial dose is 10 mg, taken after breakfast, the dosage is adjusted according to blood pressure response, the maximum dose is 80 mg.

Adverse Reactions

Similar to other angiotensin-converting enzyme inhibitors, common symptoms include cough, dizziness, headache, palpitations, and fatigue.

Precautions

1. Those who are allergic to this product. 2. Those with bilateral renal artery stenosis or solitary kidney with renal artery stenosis. 3. Patients with hyperkalemia.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

Drug Interactions

1. Indomethacin can weaken the antihypertensive effect of this product. 2. This product can increase blood potassium, so it should not be used in combination with potassium-retaining diuretics or potassium preparations.

Storage

Keep in a light-proof and airtight container.

Packaging Specification

10mg based on C21H31N3O5

Validity Period

24 months

Manufacturer

Yichang HEC Changjiang Pharmaceutical Co., Ltd.

  • Founded in:

    2001-08-08
  • Address:

    No. 38, Binjiang Road, Yidu City, Yichang City, Hubei Province
  • Tax NO.:

    91420000730842584F
  • Registered Funds:

    879.9677 million yuan
  • Website:

  • Email:

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