Levodropropizine Capsules

This product is a peripheral antitussive drug, which exerts an antitussive effect by selectively inhibiting the peripheral C-fibers of the trachea and bronchus. Its site of action is at sites associated with sensory neuropeptides in the peripheral nodes. It has a strong antitussive effect and lasts for a long time. Since it has no effect on β-adrenergic receptors, M cholinergic receptors and opioid receptors, it has fewer adverse reactions of central inhibition and is an efficient and safe antitussive drug. Data from subacute and long-term toxicity tests on rats and dogs showed that the main phenomena during the medication period were salivation, decreased intake and weight in rats, central sedation, peripheral vasodilation and increased heart rate in dogs; high doses were hepatotoxic to both animals. The test found that the maximum tolerated oral dose of the two animals was 24 mg/kg/d, which is 10 times the clinical dose. Levodropropizine has a slight effect only at 30 times the clinical dose.

Levodropropizine. Chemical name: S (-) -3- (4-phenyl-1-piperazinyl) -1,2-propanediol Molecular weight: C13H20N2O2

The content of this product is white or off-white granules or powder.

Used for dry cough and persistent cough caused by acute upper respiratory tract infection and acute bronchitis.

Oral administration: Adults should take 60 mg (1 tablet) three times a day, or once every six hours or more, or as directed by a doctor. Generally, it is recommended to stop taking the medicine after two weeks of continuous use, or as directed by a doctor. In addition, coughing is only a superficial phenomenon, and the root cause of the cough should be found and then treated.

Adverse reactions are rare, mainly manifested as gastrointestinal reactions, nausea, upper abdominal pain, indigestion, vomiting, diarrhea, central nervous system reactions, fatigue, dizziness, drowsiness, headache, palpitations, dry mouth, etc., occasionally visual impairment, rash, dyspnea are rare. Transient elevation of transaminase can be seen at high doses.

1. It is contraindicated for those who are known or may be allergic to this type of drug. 2. It is contraindicated for those with excessive sputum or decreased mucociliary clearance function. 3. It is contraindicated for pregnant women and lactating women.

Precautions for children: Use with caution in children under 2 years old. Precautions for pregnancy and lactation: Pregnant and lactating women are prohibited to use. Precautions for the elderly: There is no significant change in the pharmacokinetics of elderly patients, and there is no need to adjust the dosage or change the interval between medications.

1. According to pharmacological studies on experimental animals, this product is rapidly absorbed by the nervous system. 2. It also affects the hypoglycemic effect of insulin and digestive system drugs. 3. For particularly sensitive patients, caution should be exercised when taking inhibitory drugs at the same time. 4. Clinical studies have not found any adverse effects on the simultaneous use of other drugs for the treatment of bronchopneumonia.

Sealed and stored in a cool place.

60 mg

36 months

Hunan Jiudian Pharmaceutical Co., Ltd.

• Founded in:

  2001-01-19

• Address:

  No. 1 Jiankang Avenue, Liuyang Economic and Technological Development Zone, Changsha

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  91430100722520761D

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