Amoxicillin Tablets
Function and Efficacy
Amoxicillin is a penicillin antibiotic that has good antibacterial activity against Streptococcus such as Streptococcus pneumoniae and hemolytic Streptococcus, aerobic Gram-positive cocci such as non-penicillinase-producing Staphylococci and Enterococcus faecalis, aerobic Gram-negative bacteria such as Escherichia coli, Proteus mirabilis, Salmonella, Haemophilus influenzae, Neisseria gonorrhoeae, and Helicobacter pylori. Amoxicillin exerts its bactericidal effect by inhibiting the synthesis of bacterial cell walls, which can quickly dissolve and rupture bacteria into spherical bodies.
Ingredients
The main ingredient of this product is ampicillin, and its chemical name is 6-[D-()-2-amino-phenylacetylamino]penicillanic acid trihydrate.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| AmpicillinIngredients |
It has good antibacterial activity against Streptococcus such as Streptococcus pneumoniae and hemolytic Streptococcus, aerobic Gram-positive cocci such as non-penicillinase-producing Staphylococcus aureus and Enterococcus faecalis, aerobic Gram-negative bacteria such as Escherichia coli, Proteus mirabilis, Salmonella, Haemophilus influenzae, Neisseria gonorrhoeae and Helicobacter pylori. It exerts a bactericidal effect by inhibiting the synthesis of bacterial cell walls, which can quickly dissolve and rupture bacteria into spherical bodies. More |
69-53-4 | 26 |
Appearance
This product is in the form of capsules.
Indication
Amoxicillin is suitable for the following infections caused by sensitive bacteria (non-lactamase-producing strains): 1. Upper respiratory tract infections such as otitis media, sinusitis, pharyngitis, tonsillitis, etc. caused by hemolytic streptococci, streptococci pneumoniae, staphylococci or Haemophilus influenzae. 2. Urogenital tract infections caused by Escherichia coli, Proteus mirabilis or Enterococcus faecalis. 3. Skin and soft tissue infections caused by hemolytic streptococci, staphylococci or Escherichia coli. 4. Lower respiratory tract infections such as acute bronchitis and pneumonia caused by hemolytic streptococci, streptococci pneumoniae, staphylococci or Haemophilus influenzae. 5. Acute simple gonorrhea. 6. This product can also be used to treat typhoid fever, typhoid carriers and leptospirosis; amoxicillin can also be used in combination with clarithromycin and lansoprazole to eradicate Helicobacter pylori in the stomach and duodenum and reduce digestion.
Usage and Dosage
oral. Adults take 0.5g once every 6 to 8 hours, and the daily dose should not exceed 4g. The daily dose for children is 20-40 mg/Kg, once every 8 hours; for infants under 3 months old, the daily dose is 30 mg/Kg, once every 12 hours. Patients with severe renal impairment need to adjust the dosage, including 0.25-0.5g every 12 hours for patients with endogenous creatinine clearance 10-30ml/min; 0.25-0.5g every 24 hours for patients with endogenous creatinine clearance less than 10ml/min.
Adverse Reactions
1. Gastrointestinal reactions such as nausea, vomiting, diarrhea and pseudomembranous colitis. 2. Allergic reactions such as rash, drug fever and asthma. 3. Anemia, thrombocytopenia, eosinophilia, etc. 4. Serum aminotransferase may be slightly increased. 5. Superinfection caused by Candida or drug-resistant bacteria. 6. Occasionally, central nervous system symptoms such as excitement, anxiety, insomnia, dizziness and abnormal behavior may occur.
Precautions
It is contraindicated in patients with penicillin allergy or penicillin skin test positive.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Animal reproduction studies have shown that amoxicillin at 10 times the human dose did not damage the fertility and fetus of rats and mice. However, there is a lack of adequate controlled studies in humans. Given that animal reproduction studies cannot fully predict human reactions, pregnant women should only use this product when it is necessary. Since a small amount of amoxicillin can be secreted in breast milk, nursing mothers may cause allergies in their babies after taking it. Precautions for the elderly: Not yet clear.
Drug Interactions
1. Probenecid competitively reduces the renal tubular secretion of this product. The simultaneous use of the two can cause an increase in the blood concentration of amoxicillin and a prolonged half-life. 2. Chloramphenicol, macrolides, sulfonamides and tetracyclines interfere with the antibacterial effect of amoxicillin in vitro, but the clinical significance is unclear.
Storage
Keep away from light and store in sealed container.
Packaging Specification
0.25g
Validity Period
24 months
Manufacturer
Kunming Yuanrui Pharmaceutical Co., Ltd.
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Founded in:
1999-12-08 -
Address:
Huashi Road, Yanglin Industrial Development Zone, Yunnan -
Tax NO.:
91530127719426088A -
Registered Funds:
20.8125 million yuan -
Website:
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Email: