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Ipriflavone tablets

Function and Efficacy

This product is a drug used to improve osteoporosis-induced bone loss, and it has the effect of inhibiting bone loss in experimental osteoporosis model rats caused by ovariectomy and prednisolone. Its mechanism of action includes: directly inhibiting bone resorption; increasing the secretion of calcitonin through estrogen-like effects, indirectly producing anti-bone resorption effects; and promoting bone formation.

Ingredients

The main ingredient of this product is ipriflavone. Chemical name: 7-isopropoxy-3-phenyl-4H-1-benzopyran-4-one.

Name Description Content CAS NO. Manufacturer
IpriflavoneIngredients

It is used to improve osteoporosis-induced bone loss, and has an inhibitory effect on experimental osteoporosis rats caused by ovariectomy and prednisolone. Its mechanism of action includes: directly inhibiting bone resorption; increasing the secretion of calcitonin through estrogen-like effects, indirectly producing an anti-bone resorption effect; and promoting bone formation.

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35212-22-7 2

Appearance

This product is white or off-white tablets.

Usage and Dosage

Generally, adults take 1 tablet (200 mg) 3 times a day, orally after meals. This dose should be adjusted according to the age and symptoms of the patient.

Adverse Reactions

Rare: The incidence of adverse reactions is less than 0.1%; Occasionally: less than 0.1-5%; Common: more than 5%. 1 Important adverse reactions: 1) Peptic ulcer, gastrointestinal bleeding: Peptic ulcer, gastrointestinal bleeding or worsening symptoms are rare. When this happens, the drug should be discontinued immediately and appropriate treatment should be given. Therefore, patients with peptic ulcers and a history of peptic ulcers should use it with caution. 2) Jaundice: Jaundice is rare, so it should be closely observed. If there is any abnormality, stop using the drug immediately and take appropriate treatment. 2 Other adverse reactions: 1) Allergic reaction: Symptoms such as rash and itching are occasionally seen, and the drug should be stopped at this time. 2) Digestive organs: Occasionally nausea, vomiting, loss of appetite, stomach discomfort, heartburn, abdominal pain, abdominal distension, diarrhea, constipation, stomatitis, dry mouth, glossitis, abnormal taste, etc. 3) Nervous system: Occasionally dizziness, mild dizziness, rare headache, etc. 4) Blood: Rarely granulocytopenia, occasionally anemia, etc. 5) Liver: Occasionally, bilirubin GOT, GPT, ALP, LDH increased, rarely Y-GTP increased. 6) Kidney: Rarely, urea nitrogen and creatinine increased. 7) Others: Rarely, gynecomastia in men, if this occurs, the drug should be stopped. Rarely, tongue and lip numbness, occasionally edema and discomfort.

Precautions

1. Patients who are allergic to this product should not use it. 2. Patients with hypocalcemia should not use it. 3. Pregnant and lactating women should not use it. Children and adolescents should not use it. Elderly patients should use the drug with caution.

Special Population Medication

Precautions for children: Children and adolescents should not take this medicine. Precautions for pregnancy and lactation: Pregnant and lactating women should not take this medicine. Precautions for the elderly: Elderly patients should use this medicine with caution.

Drug Interactions

1. For animals with ovaries removed, the use of estrone can enhance the effect of estrogen, so caution should be exercised when using this drug with estrogen preparations. 2. Theophylline can increase the blood concentration of theophylline when used together, so the dosage of theophylline should be reduced and caution should be exercised when using this drug with theophylline. 3. Coumarin anticoagulants can enhance the effect of coumarin anticoagulants, so the dosage of coumarin anticoagulants should be reduced and caution should be exercised when using this drug with anticoagulants.

Storage

Store in sealed container at room temperature and keep away from moisture after opening.

Packaging Specification

0.2g

Validity Period

24 months

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