Tegafur Injection
Function and Efficacy
This product is a derivative of fluorouracil. It is activated by the liver in the body and converted into fluorouracil to exert its anti-tumor activity, interfere with DNA and RNA synthesis, and mainly acts on the S phase. It is a cell cycle-specific drug. The chemotherapy index is twice that of fluorouracil, and the toxicity is only 1/4 to 1/7 of that of fluorouracil.
Ingredients
The chemical name of this product is: 1-(tetrahydro-2-furanyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione. Its structural formula is: Molecular formula: C8H9FN2O3 Molecular weight: 200.17
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| TegafurIngredients |
This product is a derivative of fluorouracil. It is activated by the liver in the body and converted into fluorouracil to exert its anti-tumor activity, interfere with DNA and RNA synthesis, and mainly acts on the S phase. It is a cell cycle-specific drug. The chemotherapy index is twice that of fluorouracil, and the toxicity is only 1/4 to 1/7 of that of fluorouracil. More |
17902-23-7 | 10 |
Appearance
This product is an almost colorless clear liquid.
Indication
It is mainly used to treat digestive tract tumors, such as gastric cancer, colorectal cancer, pancreatic cancer, liver cancer, and can also be used for breast cancer.
Usage and Dosage
The daily dose for adults is 800-1000 mg or 15-20 mg/kg per day based on body weight. It is dissolved in 500 ml of 5% glucose injection or 0.9% sodium chloride injection and administered by intravenous drip once a day. The total amount is 20-40 g per course of treatment.
Adverse Reactions
Bone marrow suppression reaction is mild, with a decrease in white blood cells and platelets. Neurotoxic reactions include headache, dizziness, ataxia, mental state changes, etc. A few patients experience nausea, vomiting, diarrhea, and changes in liver and kidney function. Local injection sites have phlebitis, swelling, and pain. Fever, skin itching, and pigmentation are occasionally seen.
Precautions
It is contraindicated for those who are allergic to this product.
Special Population Medication
Precautions for children: This experiment has not been conducted and there is no reliable reference. Precautions for pregnancy and lactation: Do not use. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference.
Drug Interactions
Not yet clear.
Storage
Keep in a light-proof and airtight container.
Packaging Specification
5ml:0.2g
Validity Period
24 months
Manufacturer
Qingdao Jinfeng Pharmaceutical Co., Ltd.
-
Founded in:
1995-12-30 -
Address:
No. 3 Yantai Road, Laixi City, Qingdao -
Tax NO.:
91370285614301430T -
Registered Funds:
$686,200 -
Email: