Ampicillin Granules

The antibacterial effect of this product on Gram-positive cocci and bacilli (including anaerobic bacteria) is basically the same as that of penicillin, and its effect on Enterococcus faecalis is stronger than that of penicillin. Among Gram-negative bacteria, Neisseria meningitidis, Neisseria gonorrhoeae, Haemophilus influenzae, Bordetella pertussis, Brucella, Proteus mirabilis, Salmonella, etc. are sensitive to this product. Some Escherichia coli and some Shigella are also sensitive to this product, but most Shigella are resistant to this product. Other Enterobacteriaceae, Pseudomonas aeruginosa, Bacteroides fragilis, etc. are resistant to this product. This product has a certain antibacterial effect on Legionella and Campylobacter fetus. The mechanism of action of this product is to inhibit the synthesis of bacterial cell walls, causing the bacteria to rupture and dissolve rapidly.

The main ingredient of this product is ampicillin. Chemical name: 6-[D(-)-2-amino-phenylacetylamino] penicillic acid trihydrate. Chemical structure: Molecular formula C16H19N3O4S.3H2O Molecular weight: 403.45

This product is a granule with flavoring agent; it has a fragrant smell.

It is suitable for respiratory tract infections, urinary tract infections, digestive tract infections, ear, nose and throat infections, skin and soft tissue infections, and gonorrhea caused by sensitive pathogens.

Oral administration. Before taking, mix with cold boiled water to the 60 ml mark, shake well before each dose, then pour into a special small cup and take according to the following dosage.

1. The adverse reactions of this product are similar to those of penicillin. Rash is the most common reaction, which usually occurs 5 days after medication, and is urticaria or maculopapular rash; interstitial nephritis may also occur; anaphylactic shock may occasionally occur. 2. Gastrointestinal reactions such as glossitis, gastritis, nausea, vomiting, enteritis, diarrhea and mild abdominal pain are also common. 3. Granulocytopenia and thrombocytopenia are occasionally seen in patients using ampicillin. Antibiotic-related enteritis is rare, and a few patients have elevated serum alanine aminotransferase (ALT).

1. Patients who are allergic to penicillins or cephalosporins or have a positive penicillin skin test are contraindicated. 2. Patients with uric acid kidney stones or acute gout attacks are contraindicated. 3. Patients with active gastrointestinal ulcers are contraindicated.

Precautions for children: It is forbidden to use in children under 2 years old. Precautions for pregnancy and lactation: There are no strict controlled trials for the use of ampicillin in pregnant women, so pregnant women should use this product only when it is necessary. A small amount of ampicillin can be secreted from breast milk, so breastfeeding should be suspended when breastfeeding women take the drug. Precautions for the elderly: Due to the decline of biological renal function, the dosage should be appropriately reduced.

1. The half-life of this product will be prolonged when used in combination with probenecid. 2. Ampicillin and kanamycin have synergistic antibacterial effects against Escherichia coli and Proteus. 3. Allopurinol can increase the incidence of ampicillin rash, especially in hyperuricemia. 4. When chloramphenicol is used in combination with bacterial meningitis, the incidence of long-term sequelae is higher than when used alone.

Keep away from light, sealed and stored in a dry place.

0.125g (calculated as C16H19N3O4S)

Tentative 24 months

Harbin Pharmaceutical Group Co., Ltd. GENERAL Pharm. FACTORY

• Founded in:

  1994-05-19

• Address:

  No. 388, Hahei Highway, Hulan District (production base No. 109, Xuefu Road, Nangang District, No. 1, Junmin Street, Xiangfang District)

• Tax NO.:

  912301008280277137

• Registered Funds:

  -

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