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Podophyllotoxin tincture

Function and Efficacy

Pharmacology In vitro and in vivo tests have proven that this product has anti-tumor activity, can inhibit microtubule polymerization, inhibit nuclear mitosis, and stop it in the middle stage. This product is not easily absorbed orally and has serious toxic and side effects, so its systemic application is limited. In vitro efficacy tests for topical treatment of condyloma acuminatum have shown that this product can inhibit the incorporation of deoxynucleoside and DNA synthesis in cultured normal human skin keratinocytes and cervical cancer epithelial cells, hindering their division and proliferation. After external application of this product, it can inhibit the division and proliferation of epithelial cells with warty proliferation caused by human papillomavirus (HPV) infection, causing necrosis and shedding, thereby playing a role in treating condyloma acuminatum.

Ingredients

This product is a lignin anti-tumor ingredient extracted from the Podophyllum plant of the Borage family.

Appearance

This product is a colorless clear solution with an ethanol odor.

Indication

Genital warts on the external genitalia and perianal area of men and women.

Usage and Dosage

Before applying the medicine, clean the affected area with a disinfectant and astringent solution (such as potassium permanganate solution, etc.) and wipe it dry; use a special medicine swab to apply the liquid medicine to the wart, apply it all over the wart, no need to repeat and try to avoid the liquid medicine from contacting normal skin and mucous membranes; the total amount of medicine should not exceed 1 ml, and after applying the medicine, expose the affected area to let the liquid medicine dry; use the medicine twice a day for 3 consecutive days, and stop the medicine for 4 days for observation as a course of treatment. If there are still residual lesions, you can repeat a course of treatment, but no more than three courses of treatment.

Adverse Reactions

1 Most patients may experience varying degrees of burning or tingling sensations, as well as erythema, edema and erosion at the site of application after medication. 2 Erythema or superficial erosion may occur locally after shedding. These are common local reactions and there is no need to stop the medication. 3 Some patients may have severe local reactions. They can be treated with anti-inflammatory and astringent cold compresses or creams, lotions and pastes, which can quickly and significantly alleviate the symptoms. For those with severe local ulcers, edema and severe pain, treatment can be stopped if necessary. 4 A small number of patients did not have any adverse reactions during treatment. 5 No systemic adverse reactions were observed with topical treatment.

Precautions

Pregnant and lactating women are prohibited from using this drug. People who are allergic to this drug and those with unhealed wounds after surgery are prohibited from using this drug.

Special Population Medication

Precautions for children: There is currently a lack of experimental data on the use of drugs in children, and it is recommended that children should not use the drug. Precautions for pregnancy and lactation: It is forbidden for breastfeeding women. Precautions for the elderly:

Drug Interactions

Not yet clear.

Storage

Keep away from light and store in sealed container.

Packaging Specification

8ml:40mg

Validity Period

24 months.

Manufacturer

Liaoning Huawei Pharmaceutical Co., Ltd.

  • Founded in:

    2000-04-08
  • Address:

    No. 62, Zhongxing Street, Yi County
  • Tax NO.:

    91210727121061977Q
  • Registered Funds:

    14.76 million yuan
  • Email:

Other Drugs of Liaoning Huawei Pharmaceutical Co., Ltd.

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