Vitamin K1 Injection
Function and Efficacy
This product is a vitamin drug. Vitamin K is a necessary substance for the liver to synthesize factors II, VII, IX, and X. Vitamin K deficiency can cause synthesis disorders or abnormalities of these coagulation factors, and clinically bleeding tendency and prolonged prothrombin time can be seen.
Ingredients
The main ingredient of this product is vitamin K1, and its chemical name is a mixture of trans- and cis-isomers of 2-methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Vitamin K1Ingredients |
This product is a vitamin drug. Vitamin K is a necessary substance for the liver to synthesize factors II, VII, IX, and X. Vitamin K deficiency can cause synthesis disorders or abnormalities of these coagulation factors, and clinically bleeding tendency and prolonged prothrombin time can be seen. More |
84-80-0 | 27 |
Appearance
This product is a yellow to orange-yellow transparent viscous liquid.
Indication
It is used for bleeding caused by vitamin K deficiency, such as bleeding caused by obstructive jaundice, bile fistula, chronic diarrhea, etc., and low<Aclass=bluehref=http://ypk.
Usage and Dosage
1. Hypoprothrombinemia: intramuscular or deep subcutaneous injection, 10 mg each time, 1-2 times a day, the total amount within 24 hours should not exceed 40 mg. 2. Prevention of neonatal hemorrhage: 2-5 mg can be given to the mother intramuscularly or slowly intravenously 12-24 hours before delivery. 0.5-1 mg can also be injected intramuscularly or subcutaneously after the birth of the newborn, which can be repeated after 8 hours. 3. When this product is used for intravenous injection in critically ill patients, the administration rate should not exceed 1 mg/min.
Adverse Reactions
Allergic reactions are occasionally seen. Rapid intravenous injection, exceeding 5 mg/min, can cause facial flushing, sweating, bronchospasm, tachycardia, hypotension, etc. There have been reports of death from rapid intravenous injection. Intramuscular injection can cause local swelling and pain. Neonates may develop hyperbilirubinemia, jaundice and hemolytic anemia after using this product.
Precautions
It is contraindicated in patients with severe liver disease or poor liver function.
Special Population Medication
Precautions for children: Neonatal hemorrhage; intramuscular or subcutaneous injection, 1 mg each time, can be repeated after 8 hours. Precautions for pregnancy and lactation: This product can pass through the placenta, so it should be avoided as much as possible for pregnant women in labor. Precautions for the elderly: There is no research data on the safety and effectiveness of this product in the elderly.
Drug Interactions
This product may produce granular precipitation after 2 hours of mixing with phenytoin sodium, and it is easy to become turbid when mixed with vitamin C, vitamin B12, and dextran. When used in combination with dicoumarol oral anticoagulants, the effects are mutually offset. Salicylic acid, sulfonamides, quinine, quinidine, etc. also affect the effect of vitamin K1.
Storage
Store at room temperature, away from light.
Packaging Specification
1ml:10mg
Validity Period
24 months
Manufacturer
Shanxi JINXIN DOUBLE-CRANE Pharmaceutical Co., Ltd.
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Founded in:
2001-12-14 -
Address:
Sanlidun, North of Xia County, Yuncheng City, Shanxi Province -
Tax NO.:
911408287281430205 -
Registered Funds:
164.191 million yuan -
Website:
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Email: