Lomefloxacin Aspartate Sodium Chloride Injection

Lomefloxacin is a synthetic quinolone broad-spectrum antibiotic. Its antibacterial mechanism is to inhibit the activity of bacterial DNA helicase, thereby inhibiting bacterial DNA transcription and replication. It has a bactericidal effect on a variety of Gram-positive and Gram-negative bacteria.

Lomefloxacin Aspartate

This product is suitable for the following infections caused by sensitive bacteria: 1. Respiratory tract infections: acute exacerbation of chronic bronchitis, bronchiectasis with infection, acute bronchitis and pneumonia, etc. 2. Urinary and reproductive system infections: acute cystitis, acute pyelonephritis, complicated urinary tract infection, acute exacerbation of chronic urinary tract infection, acute prostatitis, simple gonorrhea, etc. 3. Infections of the abdominal cavity, bile duct, intestines, typhoid fever, etc. 4. Skin and soft tissue infections. 5. Other infections: such as sinusitis, otitis media, blepharitis, etc.

Intravenous drip, 0.2g (one bottle) each time for adults, twice a day, or as directed by a doctor.

1. Abdominal discomfort or pain, diarrhea, nausea or vomiting. 2. Central nervous system reactions: dizziness, headache, drowsiness or insomnia. 3. Allergic reactions: rash, skin itching, occasionally exudative erythema multiforme and angioneurotic edema. Among them, photosensitivity reactions are more common than other commonly used quinolones. 4. A small number of patients may have increased serum aminotransferase and BUN values and decreased peripheral blood white blood cells, which are mostly mild and transient. 5. Occasionally occur: 1. Epileptic seizures, mental abnormalities, irritability, confusion, hallucinations, tremors. 2. Hematuria, fever, rash and other manifestations of interstitial nephritis. 3. Crystalluria, more common when used in high doses. 4. Joint pain. 5. Phlebitis.

1. It is contraindicated for those who are allergic to this product or other quinolone drugs; 2. It is contraindicated for pregnant women, infants and patients under 18 years old.

1. This product has little effect on the liver metabolism and body clearance of theophylline drugs and caffeine. 2. Combination with fenbufen can cause central excitation and epileptic seizures. 3. Probenecid can delay the excretion of this product, increasing the average area under the curve (AUC) by 63%, extending the average time to peak (tmax) by 50%, and increasing the average peak concentration (Cmax) by 4%; therefore, when used in combination, toxicity may occur due to increased blood concentration of this product. 4. It can enhance the effects of oral anticoagulants such as warfarin, and prothrombin time and other items should be monitored. 5. Urine alkalinizers can reduce the solubility of this product in urine, leading to crystalluria and nephrotoxicity. 6. Combination with cyclosporine can increase the blood concentration of cyclosporine, and the blood concentration of cyclosporine must be monitored and the dosage adjusted.

Keep away from light and store in a cool dark place (keep away from light and do not exceed 20℃). Tentatively 24 months

100ml: Lomefloxacin aspartate 0.2g (calculated as C17H19F2N3O3), sodium chloride 0.85g

YANGTZE River Pharmaceutical Group Nanjing Pharmaceutical. Co., Ltd.

• Founded in:

  2001-01-16

• Address:

  No. 9 Xianlin Avenue, Qixia District, Nanjing

• Tax NO.:

  91320192726063334T

• Registered Funds:

  50 million yuan

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