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Beclomethasone dipropionate aerosol

Function and Efficacy

Beclomethasone dipropionate is a synthetic, potent topical adrenocortical hormone. Beclomethasone dipropionate aerosol has the following effects: ① Anti-inflammatory, anti-allergic, antipruritic and exudation-reducing effects, which can inhibit bronchial exudates, eliminate bronchial mucosal swelling, and relieve bronchospasm. ② It can reduce and prevent tissue response to inflammation, and can eliminate fever, redness and swelling caused by local non-infectious inflammation, thereby reducing the manifestations of inflammation. ③ Immunosuppressive effect: prevent or inhibit cell-mediated immune responses, delayed allergic reactions, and reduce the expansion of primary immune responses. ④ This product has a very weak effect on sodium retention and hepatic gluconeogenesis when applied topically, and has no male, female and protein anabolic hormone-like effects, and has no significant effect on body temperature and urine. Inhalation administration is more effective than oral administration for bronchial asthma.

Ingredients

The main ingredient of this product is beclomethasone dipropionate. Its chemical name is 16b-methyl-11b,17a,21-trihydroxy-9a-chloropregnane-1,4-diene-3,20-dione-17,21-dipropionate. Molecular formula: C28H37ClO7 Molecular weight: 521.05

Name Description Content CAS NO. Manufacturer
Beclomethasone dipropionateIngredients

It has anti-inflammatory, anti-allergic, antipruritic and exudate-reducing effects, can inhibit bronchial exudate, eliminate bronchial mucosal swelling, and relieve bronchospasm; it can reduce and prevent tissue response to inflammation, and can eliminate fever, redness and swelling caused by local non-infectious inflammation, thereby reducing the manifestation of inflammation; immunosuppressive effect: prevent or inhibit cell-mediated immune response, delayed allergic reaction, and reduce the expansion of primary immune response. Topical application has very weak effects on sodium retention and hepatic gluconeogenesis, and has no male, female and protein anabolic hormone-like effects, and has no significant effect on body temperature and urine. Inhalation administration is more effective than oral administration for bronchial wheezing.

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5534-09-8 26

Appearance

The content of this product in a pressure-resistant metal container with a quantitative valve system is a white or slightly yellow suspension. When the valve is pressed, the liquid medicine is sprayed out quantitatively in the form of mist particles.

Indication

This product is used for the lungs and has no obvious systemic effect. It can be used for the treatment and prevention of asthma. It is used for bronchial asthma, including infectious asthma, allergic asthma and asthma patients who rely on hormone treatment, especially when bronchodilators or other antiasthmatic drugs such as sodium cromoglycate are not enough to control asthma.

Usage and Dosage

For nasal spray only. Suitable for adults and children over six years old. Dosage: The recommended dosage is 2 pinches per nostril, 2 times a day. You can also use 1 pinch per nostril, 3 to 4 times a day. The daily dosage should not exceed 8 pinches (400 mu; g). For the best effect, the drug should be used regularly. The highest effect may not be achieved in the first few uses.

Adverse Reactions

1. Some patients may experience adverse reactions such as dryness or burning sensation in the nose or throat, sneezing or mild nose bleeding. 2. Nasal septum perforation, increased intraocular pressure or glaucoma in very few patients may be related to the use of beclomethasone dipropionate nasal spray.

Precautions

It is contraindicated in patients who are allergic to beclomethasone dipropionate.

Special Population Medication

Precautions for children: Use with caution in infants Precautions for pregnancy and lactation: Use with caution in pregnant women Precautions for the elderly: Excessive dosage of this product (0.8 mg/d) may cause a series of systemic adverse reactions of glucocorticoids.

Drug Interactions

1. This product may affect the uptake, clearance and conversion rate of iodine by the human thyroid gland. 2. Insulin can produce an antagonistic effect with this product, and diabetics should pay attention to adjusting the dosage.

Storage

Keep tightly closed in a cool, dark place.

Validity Period

36 months

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