Fluticasone Propionate Cream

Fluticasone propionate is a highly effective glucocorticoid with local anti-inflammatory effects. After transdermal administration, the inhibitory effect on the HPA axis is very weak, so its therapeutic index is higher than most commonly used steroid preparations. Subcutaneous injection produces a strong systemic glucocorticoid effect, but the oral effect is weak, which may be due to metabolic inactivation. In vitro tests have shown that this drug has a strong affinity and agonist effect on the human glucocorticoid receptor. Fluticasone propionate has no expected pheromone effect and has no obvious effect on the central nervous system, peripheral nervous system, gastrointestinal tract, cardiovascular system, and respiratory system.

The main ingredient of this product is fluticasone propionate; its chemical name is: (6α, 11β, 16α, 17α)-6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-androsta-1,4-diene-17-carboxylic acid thioate, S-fluoromethyl ester;

This product is a white cream.

1. Suitable for various inflammatory and pruritic skin diseases in adults that can be relieved by corticosteroids, such as eczema including atopic eczema and discoid eczema; nodular prurigo; psoriasis (except generalized plaque type); neurodermatoses including simple lichen; lichen planus; seborrheic dermatitis; contact allergy; discoid lupus erythematosus; adjuvant medication for systemic steroid treatment of generalized erythema, insect bite dermatitis; miliary rash; 2. Suitable for children over 1 year old (including 1 year old) who are ineffective with low-efficiency corticosteroids. Children under the guidance of a doctor can use this product to relieve inflammation and itching caused by atopic dermatitis, as well as other skin diseases that can be relieved by corticosteroids.

Eczema/Dermatitis Adults and children over one year old (inclusive), apply a thin layer of cream to the affected area once a day. Other indications Apply a thin layer of cream to the affected area twice a day. Duration of use This product should be used daily until the symptoms of the disease are controlled. The frequency of medication should be controlled at the lowest effective dose. When children use this product, if the symptoms do not improve after 7-14 days of treatment, the drug should be discontinued and re-evaluated. If the symptoms are controlled (usually within 7-14 days), the frequency of medication should be reduced to the minimum effective dose and the shortest medication time. It is recommended to use this product continuously for no longer than 4 weeks. This product is for topical use.

Fluticasone propionate has good tolerability. In placebo-controlled clinical trials, the most common side effects are: skin infection, infectious eczema, viral warts, herpes simplex, impetigo, atopic dermatitis, eczema, worsening of eczema, erythema, burning sensation, stinging, skin irritation, itching, worsening itching, folliculitis, blisters, finger numbness and dry skin. In open clinical trials conducted in children, common side effects are: burning sensation, dark erythema, erythematous rash, facial telangiectasia, non-facial telangiectasia, and urticaria. If allergic reactions occur, the drug should be discontinued immediately. Adverse reactions such as inflammation, folliculitis, acne-like rash, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, skin atrophy, striae and prickly heat are rare, but when occlusive therapy is used.

1. This product is contraindicated for those who are allergic to any of the ingredients in it; 2. This product is contraindicated for those with rosacea, acne vulgaris, rosacea, perioral dermatitis, and primary skin viral infections (such as herpes simplex and varicella); 3. This product is contraindicated for those with perianal and vulvar pruritus; 4. This product is contraindicated for those with primary skin infections caused by fungi or bacteria; 5. This product is contraindicated for skin diseases in infants under 1 year old, including dermatitis and diaper rash.

Precautions for children: It is forbidden to use in infants under 1 year old with skin diseases. Precautions for pregnancy and lactation: It is forbidden to use in pregnant women, and should be used with caution in lactating women. Precautions for the elderly: It is not clear yet.

Not yet clear.

Store below 30°C.

0.05%

24 months

Hubei Heng'an Fulin Pharmaceutical Co., Ltd.

• Founded in:

  2001-06-15

• Address:

  Hubei Yichang Hengan Pharmaceutical Biological Industrial Park

• Tax NO.:

  9142050072831140XW

• Registered Funds:

  60 million yuan

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