On ECHEMI
Home > Drugs > Shenmai Injection

Shenmai Injection

Function and Efficacy

1. It has anti-shock effect. Shenmai injection can increase the blood pressure of rats with endotoxin shock, with a good dose-effect correlation. 2. It has anti-heart failure effect. Shenmai injection can improve the left ventricular systolic and diastolic function of rats with heart failure, reduce the plasma levels of angiotensin II, endothelin, and atrial natriuretic peptide; improve the left ventricular systolic and diastolic function of rats with heart failure; reduce the calcium overload of ischemic myocardial cells, and play a myocardial protective role. 3. It has anti-multi-organ ischemia effect. Shenmai injection can increase the activity of superoxide dismutase (SOD), promote the production of nitric oxide (NO), and has a certain protective effect on ischemia-reperfusion injury caused by hypovolemic shock in rabbits; it has a protective effect on myocardial ultrastructural damage caused by ischemia-reperfusion injury; it can remove oxygen free radicals produced during liver ischemia-reperfusion, and has a protective effect on the structural and functional damage of hepatocytes caused by rat liver ischemia-reperfusion; it reduces renal necrosis in animals with renal ischemia-reperfusion injury model. 4. It has anti-inflammatory effect. Shenmai injection can significantly increase the low body temperature and low peripheral blood leukocyte count of mice with endotoxin-induced systemic inflammatory response syndrome and multiple organ dysfunction syndrome model, improve the hypoglycemia state of mice caused by endotoxin, and reduce the pathological changes of various organs caused by endotoxin. 5 It has the effect of enhancing immune function. Shenmai injection can significantly increase the content of immunoglobulin G (IgG), immunoglobulin M (IgM), and immunoglobulin A (IgA) in rats. 6 It has a protective effect on the heart. Shenmai injection has a protective effect on the cardiac toxicity of rats caused by doxorubicin.

Ingredients

Red ginseng and Ophiopogon japonicus.

Appearance

This product is a light yellow to light brown clear liquid.

Usage and Dosage

Intramuscular injection: 2-4 ml at a time, once a day. Intravenous drip: 10-60 ml at a time (diluted with 250-500 ml of 5% glucose injection) or as directed by a doctor.

Adverse Reactions

l If you feel unwell during the use of this product, tell your doctor or pharmacist as soon as possible. Stop using it in case of emergency. 2 If you are satisfied with the efficacy of this product, the following are possible adverse reactions (according to the 3rd Information Bulletin of Adverse Drug Reaction of the National Center for Adverse Drug Reaction Monitoring), but not everyone will definitely experience them, and you may not encounter any of them, so don't be nervous. 1) You may have allergic reactions, such as palpitations, shortness of breath, chest tightness, facial flushing, etc. 2) There are 6 cases of anaphylactic shock reported in the literature. 3) There are 5 cases of dyspnea reported in the literature. 4) There is 1 case of death from heart failure reported in the literature.

Precautions

Patients with a history of allergic reaction or severe adverse reaction to this product are contraindicated.

Special Population Medication

Precautions for children: Forbidden for newborns and infants. Precautions for pregnancy and lactation: Use with caution for pregnant women. Precautions for the elderly: Use with caution for the elderly.

Drug Interactions

l If you are taking any other medicines, please tell your doctor or pharmacist, including any over-the-counter medicines purchased from pharmacies, supermarkets or health food stores. 2 This product should not be mixed with antibiotics. 3 This product contains ginseng and should not be used at the same time as medicines containing Veratrum or Pentaphyllum. 4 Do not drink tea or eat radish during medication to prevent affecting the efficacy of the medicine. 5 Avoid smoking, drinking, spicy and greasy foods during medication. 6 Doctors and pharmacists may have more information on precautions for using Shenmai Injection.

Storage

Keep sealed.

Packaging Specification

20ml per bottle

Validity Period

18 months

Manufacturer

China Resources Sanjiu (Yaan) & Pharmaceutical Co., Ltd.

  • Founded in:

    1995-11-09
  • Address:

    No. 1, Nanba Middle Street, Yucheng District, Ya'an City, Sichuan Province
  • Tax NO.:

    91511800621471147L
  • Registered Funds:

    100 million yuan
  • Website:

  • Email:

Other Drugs of China Resources Sanjiu (Yaan) & Pharmaceutical Co., Ltd.

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.