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Pilocarpine Nitrate Tablets

Function and Efficacy

Pilocarpine is a cholinergic drug. After oral absorption, it directly stimulates the M-cholinergic receptors of the sweat glands, salivary glands, lacrimal glands, digestive tract and respiratory tract gland cells to increase secretion, which is most obvious in the sweat glands and salivary glands. This product can also stimulate the M-cholinergic receptors of the smooth muscles of the digestive tract to increase gastrointestinal motility and tension. It can also excite the smooth muscles of the ureters, bladder, etc. and the muscarinic receptors on the secretory glands.

Ingredients

The main component of this product is pilocarpine nitrate. Its chemical name is 4-[(1-methyl-1H-imidazol-5-yl)methyl]-3-ethyldihydro-2(3H)-furanone nitrate. Molecular formula: C11H16N2O2HNO3 Molecular weight: 271.27

Name Description Content CAS NO. Manufacturer
Pilocarpine nitrateIngredients

Pilocarpine is a cholinergic drug that directly stimulates the M-cholinergic receptors in the sweat glands, salivary glands, lacrimal glands, digestive tract and respiratory tract gland cells to increase secretion, which is most obvious in the sweat glands and salivary glands. It can also stimulate the M-cholinergic receptors in the smooth muscles of the digestive tract to increase gastrointestinal motility and tension. It can also work by exciting the smooth muscles of the ureters, bladders, etc. and the muscarinic receptors on the secretory glands.

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148-72-1 7

Appearance

White flakes, easily deteriorate when exposed to light.

Indication

Xerostomia after radiotherapy for head and neck tumors; drug-induced xerostomia; xerostomia caused by salivary gland diseases.

Usage and Dosage

Oral, 4 mg each time, 3 times a day or as directed by a physician

Adverse Reactions

Symptoms may include drooling, sweating, gastrointestinal discomfort, abdominal pain, etc.

Precautions

Patients with bradycardia, hypotension, coronary heart disease, gastrointestinal spasm, diarrhea, abdominal pain, peptic ulcer, urinary tract obstruction, mechanical intestinal obstruction, ureteral spasm, biliary tract disease, asthma, hyperthyroidism, epilepsy, tremor paralysis, etc.

Special Population Medication

Precautions for children: Children should be used with caution, because they are light in weight and are prone to overdose, causing systemic poisoning. Precautions for pregnancy and lactation: The safety of this product for pregnant and lactating women has not yet been determined, so it should be used with caution. Precautions for the elderly: This product has not been tested and there is no reliable reference literature.

Drug Interactions

When used in combination with other cholinergic drugs or anticholinesterase drugs (such as neostigmine), the effect of this product may be increased and the dosage of this product must be adjusted. Local anticholinergic drugs (such as atropine) may counteract the pharmacological effects of this product.

Storage

Keep away from light, tightly closed, in a cool and dark place.

Packaging Specification

2mg

Validity Period

24 months

Manufacturer

Penglai Nuokang Pharmaceutical Co., Ltd.

  • Founded in:

    2002-06-07
  • Address:

    No. 118, Jinchuang Road, Penglai City, Shandong Province
  • Tax NO.:

    913706007392965167
  • Registered Funds:

    92.7117 million yuan
  • Email:

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