Sodium norcantharinate and sodium chloride injection
Function and Efficacy
In vitro tests of this product have a destructive or inhibitory effect on the morphology or proliferation of cell lines such as liver cancer, esophageal cancer, laryngeal cancer, lung cancer, and cervical cancer. In vivo tests, it has a certain inhibitory effect on mouse Ehrlich ascites carcinoma, sarcoma-180, and solid liver cancer. It can increase the respiratory control rate and lysosomal enzyme activity of mitochondria in ascites liver cancer H22 mouse cancer cells, interfere with cancer cell division, block them in the M phase, and affect their cycle speed. This product can destroy the skeleton of cancer cells (microfilaments, microtubules), affect the ultrastructure of cancer cells, and cause damage to mitochondria, microvilli, and plasma membranes. It can inhibit DNA synthesis of cancer cells, but it does not inhibit normal bone marrow cells, and can increase white blood cells.
Ingredients
The main ingredient of this product is sodium norcantharidin, and its chemical name is: 1,2-cis-3,6-oxo-hexahydrophthalic acid sodium salt.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| SodiuM DeMethylcantharidateIngredients |
In vitro tests have destructive or inhibitory effects on the morphology or proliferation of cell lines such as liver cancer, esophageal cancer, laryngeal cancer, lung cancer, and cervical cancer; in vivo tests have a certain inhibitory effect on Ehrlich ascites carcinoma, sarcoma-180, and solid liver cancer in mice, and can increase the respiratory control rate and lysosomal enzyme activity of mitochondria in ascites liver cancer H22 mice, interfere with cancer cell division, block it in the M phase, and affect its cycle speed; it can destroy the skeleton of cancer cells (microfilaments and microtubules), affect the ultrastructure of cancer cells, and cause damage to mitochondria, microvilli, and plasma membranes; it can inhibit DNA synthesis of cancer cells, but has no inhibitory effect on normal bone marrow cells, and can increase white blood cells. More |
13114-29-9 | 0 |
Appearance
This product is a colorless clear liquid.
Indication
It is used for liver cancer, esophageal cancer, stomach and cardia cancer, lung cancer, and leukopenia. It can also be used as a preoperative medication for cancer or in combined chemotherapy.
Usage and Dosage
Slow intravenous drip. 30 mg at a time or as directed by your doctor.
Adverse Reactions
If the single injection volume exceeds 30 mg, some patients may experience gastrointestinal symptoms such as nausea and vomiting.
Drug Interactions
Not yet clear.
Storage
Store in a sealed container. The validity period is tentatively 24 months.
Packaging Specification
250ml: 30mg (as norcantharidin) and 2.25g sodium chloride
Manufacturer
Shandong Hualu Pharmaceutical Co., Ltd.
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Founded in:
1998-11-28 -
Address:
No. 1 Hualu Street, Zhenxing Street, Chiping District, Liaocheng City, Shandong Province -
Tax NO.:
91371523168091268M -
Registered Funds:
50 million yuan -
Website:
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Email: