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Sodium Chloride Injection

Function and Efficacy

Sodium chloride is an electrolyte supplement. Sodium and chloride are important electrolytes in the body, mainly present in extracellular fluid, and play a very important role in maintaining normal blood and extracellular fluid volume and osmotic pressure. The normal serum sodium concentration is 135-145mmol/L, accounting for 92% of plasma cations and 90% of total osmotic pressure, so the amount of plasma sodium plays a decisive role in osmotic pressure. The normal serum chloride concentration is 98-106mmol/L. Sodium and chloride ions in the human body are mainly regulated by the hypothalamus, posterior pituitary and kidneys to maintain the stability of body fluid volume and osmotic pressure.

Ingredients

The main ingredients of this product and its chemical name: Sodium chloride

Name Description Content CAS NO. Manufacturer
Sodium chlorideIngredients

Sodium chloride is an electrolyte supplement. Sodium and chloride are important electrolytes in the body, mainly present in extracellular fluid, and play a very important role in maintaining normal blood and extracellular fluid volume and osmotic pressure. The normal serum sodium concentration is 135-145mmol/L, accounting for 92% of plasma cations and 90% of total osmotic pressure, so the amount of plasma sodium plays a decisive role in osmotic pressure. The normal serum chloride concentration is 98-106mmol/L. Sodium and chloride ions in the human body are mainly regulated by the hypothalamus, posterior pituitary and kidneys to maintain the stability of body fluid volume and osmotic pressure.

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7647-14-5 43

Appearance

This product is a colorless, clear liquid with a slightly salty taste.

Indication

Water loss due to various reasons, including hypotonic, isotonic and hypertonic water loss; hyperosmotic non-ketotic diabetic coma, the use of isotonic or hypotonic sodium chloride can correct water loss and hyperosmotic state; hypochloremic metabolic alkalosis; external use of normal saline to rinse eyes, wash wounds, etc.; also used for obstetric water bag induction of labor.

Usage and Dosage

Intravenous drip. For patients with severe hypokalemia or those who cannot take oral medication. The dose, concentration and speed of potassium supplementation are determined according to the clinical condition, blood potassium concentration and improvement of the potassium deficiency pattern on the electrocardiogram. The potassium concentration should not exceed 3.4g/l (45mmol/L), the potassium supplementation rate should not exceed 0.75g/h (10mmol/h), and the daily potassium supplementation amount should be 3-4.5g (40-60mmol). When potassium deficiency in the body causes severe rapid ventricular ectopic arrhythmias, such as torsades de pointes, short bursts, recurrent multiline ventricular tachycardia, ventricular flutter and other life-threatening severe arrhythmias, the potassium salt concentration should be high (0.5%, or even 1%), the drip rate should be fast, 1.5g/h (20mmol/h), and the potassium supplementation amount should reach 10g or more per day.

Adverse Reactions

1. Excessive and rapid infusion can cause water and sodium retention, resulting in edema, increased blood pressure, increased heart rate, chest tightness, dyspnea, and even acute left heart failure. 2. Excessive and rapid administration of hypotonic sodium chloride can cause hemolysis, cerebral edema, etc.

Precautions

Not yet clear.

Drug Interactions

When used as a drug solvent or diluent, attention should be paid to incompatibilities between drugs.

Storage

Keep tightly closed.

Packaging Specification

100ml:0.9g

Manufacturer

Jiangsu Hengrui Pharmaceuticals Co., Ltd.

  • Founded in:

    1997-04-28
  • Address:

    No. 38 Huanghe Road, Lianyungang Economic and Technological Development Zone
  • Tax NO.:

    9132070070404786XB
  • Registered Funds:

    6,379,002,274 yuan
  • Website:

  • Email:

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