Erythromycin suppositories

This product belongs to the macrolide antibiotics. It has antibacterial activity against Staphylococcus (except methicillin-resistant strains), various groups of streptococci and Gram-positive bacilli. Neisseria, Haemophilus influenzae, Bordetella pertussis, etc. are also sensitive to this product. This product also has antibacterial effects on various anaerobic bacteria except Bacteroides fragilis and Fusobacterium. It also has inhibitory effects on Legionella, Campylobacter fetus, certain spirochetes, Mycoplasma pneumoniae, Rickettsia and Chlamydia. This product can penetrate the bacterial cell membrane and reversibly bind to the 50S subunit of the bacterial ribosome near the donor site ("P" site), blocking the transfer RNA (t-RNA) from binding to the "P" site, and also blocking the displacement of the polypeptide chain from the acceptor site ("A" site) to the "P" site, thereby inhibiting bacterial protein synthesis.

The main ingredient of this product is erythromycin.

This product is a white bullet-shaped suppository.

1. This product is used as an alternative drug for the following infections in patients allergic to penicillin: acute tonsillitis, acute pharyngitis, sinusitis caused by hemolytic streptococci, pneumococcus, etc.; scarlet fever and cellulitis caused by hemolytic streptococci; diphtheria and diphtheria carriers; gas gangrene, anthrax, tetanus, actinomycosis; syphilis; listeria, etc. 2. Legionnaires' disease. 3. Chlamydia and mycoplasma pneumonia. 4. Urinary and reproductive system infections caused by chlamydia and mycoplasma. 5. Chlamydia trachomatis conjunctivitis. 6. Neisseria gonorrhoeae infection. 7. Oral infection caused by anaerobic bacteria. 8. Campylobacter jejuni enteritis. 9. Whooping cough, etc.

Rectal administration. 0.2g each time, twice a day. Usage: Take out the suppository and insert it into the anus 2 cm deep with the medicine delivery device. You can also wear a finger cot and deliver the medicine with your fingers.

1. Hepatotoxicity is rare, and patients may experience fatigue, fever, abnormal liver function, and occasionally jaundice. 2. Allergic reactions manifest as drug fever, rash, eosinophilia, etc., with an incidence of about 0.5% to 1%. 3. Others, occasionally arrhythmia, oral or vaginal candidiasis.

1. It is contraindicated for patients who are allergic to erythromycin. 2. It is contraindicated for patients with diarrhea. 3. It is contraindicated for patients with severe liver dysfunction.

Precautions for children: 100,000 units (each containing 0.1 g of erythromycin) suppositories should be used. Children should use 20-30 mg per kg of body weight per day or follow the doctor's advice. Precautions for pregnancy and lactation: 1. Erythromycin can pass through the placenta and enter the fetal circulation. The concentration is generally not high, and there is no report on the effect on the fetus in the literature, but pregnant women should still weigh the pros and cons when using it. 2. A considerable amount of erythromycin enters breast milk, and the pros and cons should be considered when using it in lactating women. Precautions for the elderly: Not yet clear.

1. Erythromycin can inhibit the metabolism of antiepileptic drugs such as carbamazepine and valproic acid, resulting in increased blood concentrations of the latter and toxic reactions. The combination of erythromycin and fentanyl can inhibit the metabolism of the latter and prolong its duration of action. The combination of erythromycin and antihistamines such as astemizole or terfenadine can increase cardiac toxicity, and the combination with cyclosporine can increase the blood concentration of the latter and produce nephrotoxicity. 2. Erythromycin has an antagonistic effect on chloramphenicol and lincomycins, and its co-use is not recommended. 3. This product is an antibacterial agent and can interfere with the bactericidal efficacy of penicillin. Therefore, when a rapid bactericidal effect is required, such as in the treatment of meningitis, the two should not be used at the same time. 4. Patients who have been taking warfarin for a long time may experience a prolonged prothrombin time when using erythromycin, thereby increasing the risk of bleeding. Elderly patients should pay special attention. When the two must be used together,

Keep away from light and store in a sealed container.

0.2g (200,000 units)

24 months

Shanxi Dayin Children's Pharmaceutical Co., Ltd.

• Founded in:

  2015-12-14

• Address:

  No. 20 Huagong Road, Jinyuan District

• Tax NO.:

  91140100MA0GRM9W8E

• Registered Funds:

  50 million yuan

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