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Piroxicam Tablets

Function and Efficacy

It is a non-steroidal anti-inflammatory drug with analgesic, anti-inflammatory and antipyretic effects. This product exerts its pharmacological effects by inhibiting cyclooxygenase, reducing the synthesis of local prostaglandins in tissues, inhibiting the chemotaxis of leukocytes and the release of lysosomal enzymes. Acute toxicity test results: The oral LD50 of mice is 360mg/kg.

Ingredients

The main ingredients of this product and their chemical names are: The main ingredient of this product is piroxicam, and its chemical name is 2-methyl-4-hydroxy-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide.

Name Description Content CAS NO. Manufacturer
PiroxicamIngredients

It is a non-steroidal anti-inflammatory drug with analgesic, anti-inflammatory and antipyretic effects. This product exerts its pharmacological effects by inhibiting cyclooxygenase, reducing the synthesis of prostaglandins in local tissues, inhibiting the chemotaxis of leukocytes and the release of lysosomal enzymes.

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36322-90-4 33

Appearance

This product is an off-white, slightly yellowish green tablet or a sugar-coated tablet. After removing the sugar coating, it appears off-white or slightly yellowish green.

Indication

Used for symptomatic treatment of pain and swelling in various arthritis and soft tissue lesions.

Usage and Dosage

Oral administration, usual adult dose: 20 mg once a day, or 10 mg twice a day. Take after meals.

Adverse Reactions

1 Gastrointestinal adverse reactions such as nausea, stomach pain, decreased appetite and indigestion are the most common, of which 3.5% require drug withdrawal. The incidence of gastric ulcers increases significantly when the dosage is greater than 20 mg per day, and some are accompanied by bleeding or even perforation. 2 Neutropenia, eosinophilia, increased blood urea nitrogen, dizziness, vertigo, tinnitus, headache, general weakness, edema, rash or itching, etc. 3 Abnormal liver function, thrombocytopenia, hyperhidrosis, skin ecchymosis, peeling, erythema multiforme, toxic epithelial necrosis, bullous erythema multiforme (Stevens-Johnson syndrome), skin allergic reaction to light, blurred vision, red and swollen eyes, hypertension, hematuria, hypoglycemia, depression, insomnia

Precautions

It is contraindicated for patients who are allergic to this product, have peptic ulcers, or chronic gastric diseases.

Special Population Medication

Precautions for children: Forbidden. Precautions for pregnancy and lactation: 1. Pregnant women who take the drug in the last three months of pregnancy may inhibit labor and cause dystocia, and may also experience gastrointestinal toxicity. In addition, long-term use of the drug in the late pregnancy may cause early closure or stenosis of the fetal ductus arteriosus, resulting in persistent pulmonary hypertension and heart failure in the newborn. Precautions for pregnant women: Use with caution. 2. This product may cause a decrease in milk secretion, which is related to the dosage. It is not suitable for lactating women. Precautions for the elderly: Use with caution.

Drug Interactions

1. When drinking alcohol or taking it with other anti-inflammatory drugs, gastrointestinal adverse reactions increase. 2. When used with anticoagulants such as dicoumarol, the latter's effect is enhanced and the bleeding tendency is significant, so the dosage should be adjusted. 3. When used with aspirin, the blood concentration of this product can drop to 80% of the normal concentration, and the risk of gastrointestinal ulcer formation and bleeding tendency increases.

Storage

Keep away from light and store in sealed container.

Packaging Specification

10mg

Validity Period

24 months

Manufacturer

Jinghua Pharmaceutical Group Co., Ltd.

  • Founded in:

    1994-01-03
  • Address:

    No. 9 Xingtai Road, Gangzha Economic Development Zone, Nantong City
  • Tax NO.:

    91320600138297660P
  • Registered Funds:

    814.180908 million yuan
  • Website:

  • Email:

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