Ursodeoxycholic acid tablets

This product can increase the secretion of bile acid and cause changes in the composition of bile acid, increasing the content of this product in bile. This product can also significantly reduce the molar concentration of cholesterol and cholesterol esters in human bile and the saturation index of cholesterol, thus facilitating the gradual dissolution of cholesterol in stones.

The main ingredient of this product is ursodeoxycholic acid. Its chemical name is 3a,7b-dihydroxy-5b-cholestane-24-acid.

Ursodeoxycholic acid is a white crystalline powder, odorless and bitter. It is almost insoluble in water, easily soluble in ethanol and glacial acetic acid, slightly soluble in imitation, and very slightly soluble in ether. This product is a white tablet.

This product is used for cholesterol gallstone formation and bile-deficient steatorrhea. It can also be used to prevent drug-induced stone formation and treat steatorrhea (after ileal resection).

Adult oral administration: 8-10 mg/kg daily, divided into two doses during the morning and evening meals. The shortest course of treatment is 6 months. If there is no improvement in ultrasound examination and cholecystography after 6 months, the drug can be discontinued; if the stones have partially dissolved, continue to take the drug until the stones are completely dissolved.

This product has less toxicity and side effects than chenodeoxycholic acid. It generally does not cause diarrhea. Other occasional adverse reactions include constipation, allergies, headaches, dizziness, pancreatitis, and tachycardia. During the treatment period, it may cause gallstone calcification and soft stools. [Contraindications] It is contraindicated in patients with complete bile duct obstruction and severe liver dysfunction.

Acute biliary infection, biliary obstruction, pregnant and lactating women.

Precautions for children: This experiment has not been conducted and there is no reliable reference. Precautions for pregnancy and lactation: Pregnant and lactating women are prohibited. Precautions for the elderly: Elderly patients should use with caution.

Ursodeoxycholic acid accounts for a small part of human bile. After oral administration of ursodeoxycholic acid, the cholesterol saturation in bile is reduced by inhibiting the reabsorption of cholesterol in the intestine and reducing the secretion of cholesterol into bile. Cholesterol stones are gradually dissolved, probably due to the dispersion of cholesterol and the formation of liquid crystals. According to existing knowledge, the treatment of liver and cholestatic diseases with ursodeoxycholic acid capsules is mainly based on the relative replacement of lipophilic, detergent-like toxic bile acids by hydrophilic, cytoprotective and non-cytotoxic ursodeoxycholic acid, as well as the promotion of hepatocyte secretion and immunomodulation.

Store away from light

50mg

36 months

Shanghai Shikangte Pharmaceutical Co., Ltd.

• Founded in:

  1995-05-27

• Address:

  No. 699, Baofeng Road, Jiading District, Shanghai

• Tax NO.:

  91310114133660491F

• Registered Funds:

  60 million yuan

• Email:

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