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Pimidic acid tablets

Function and Efficacy

This product is a quinolone antibacterial drug that acts on bacterial DNA gyrase to interfere with bacterial DNA synthesis, thereby causing bacterial death. It has antibacterial effects on Gram-negative bacteria such as Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis, Serratia, Salmonella typhi, Shigella, Pseudomonas aeruginosa, etc.

Ingredients

The main ingredients of this product are: Pimidic acid

Name Description Content CAS NO. Manufacturer
Pipemidic acidIngredients

This product is a quinolone antibacterial drug that acts on bacterial DNA gyrase to interfere with bacterial DNA synthesis, thereby causing bacterial death. It has antibacterial effects on Gram-negative bacteria such as Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis, Serratia, Salmonella typhi, Shigella, Pseudomonas aeruginosa, etc.

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51940-44-4 3

Appearance

This product is light yellow tablet.

Indication

Used for urinary tract infections and bacterial intestinal infections caused by sensitive Gram-negative bacteria.

Usage and Dosage

Adults take 0.5g orally at a time and 1 to 2g per day.

Adverse Reactions

This product has low toxicity, and the main adverse reactions are gastrointestinal reactions such as nausea, belching, upper abdominal discomfort, loss of appetite, loose stools or constipation. Rashes or systemic itching are rare; dizziness, headache, transient increase in serum aminotransferase, etc. are occasionally seen. The above adverse reactions are all mild and can be recovered on their own after stopping the drug.

Precautions

It is contraindicated in patients who are allergic to this product and nalidixic acid.

Special Population Medication

Precautions for children: The safety of this product in infants and adolescents under 18 years of age has not been established. However, this product can cause joint lesions when used in several young animals. Therefore, it is not suitable for children and adolescents under 18 years of age. Precautions for pregnancy and lactation: Animal experiments show that this product can inhibit the development of cartilage in young animals. Pregnant women and lactating women should not use it. Precautions for the elderly: The dosage of elderly patients should be adjusted according to their renal function.

Drug Interactions

1. Probenecid can inhibit the renal tubular secretion of this product. When used together, the latter's blood concentration increases and the half-life is prolonged. 2. This product can reduce the clearance of caffeine from the liver, prolonging the latter's half-life. Avoid using it together, or monitor the blood concentration of caffeine. 3. This product can significantly reduce the clearance of theophylline, causing the latter's blood concentration to increase, which is prone to toxic reactions. The two should not be used together. If they need to be used together, theophylline concentration should be monitored and the dosage should be adjusted. 4. It often has a synergistic effect with gentamicin, carbenicillin, penicillin, etc.

Storage

Sealed storage

Packaging Specification

0.25g

Validity Period

24 months

Manufacturer

Shandong Xinhua Pharmaceutical Company Limited

  • Founded in:

    1998-11-20
  • Address:

    Chemical Industry Zone, Zibo High-tech Industrial Development Zone
  • Tax NO.:

    91370300164103727C
  • Registered Funds:

    682,407,635 yuan
  • Website:

  • Email:

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