Sertraline
1 Inquiries
79617-96-2
2026-10-06
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Product Description
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DescriptionKeywordsQuick DetailsProName:
Sertraline
CasNo:79617-96-2
Molecular Formula:C17H17Cl2N
Appearance:white crystalline powder, odorless
Application:Other apis
DeliveryTime:prompt shipment
PackAge:25kg/drum
Port:Hangzhou,Shanghai,China
ProductionCapacity:/
Purity:98.5%min
Storage:cool and dry
Transportation:by sea ,air or express
LimitNum:1 Kilogram
Superiority
Description： white crystalline powder, odorless Specific optical rotation ：+37.5°~+42.5° Identification： Chemical iden…
Details
Description： white crystalline powder, odorless
Specific optical rotation ：+37.5°~+42.5°
Identification：
Chemical identification:
(1) should be positive reaction
(2) infrared light absorption patterns should be
consistent with the reference substance of the map
(3) UV: 282 nm and 274nm, 266nm with maximum
absorption; in the 279 nm and 270nm a minimum absorption
Related substances:Not more than 1.0% 0.43%
ethanol: Not more than 0.5%
Ethyl Acetate: Not more than 0.5%
Tetrahydrofuran:Not more than 0.072%
Optical isomers: Not more than 1%
Loss on drying :Not more than 0.5%
Residue on ignition :Not more than 0.1%
Heavy metals :Not more than 10ppm <10ppm
Assay C17H17NCI HCl : Not Less than 98.5%
ECHEMI Editorial ReferenceChEBI: A member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer). A selective serotonin-reuptake inhibito (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder.
Solid
Sertraline is a member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder. It has a role as an antidepressant and a serotonin uptake inhibitor. It is a member of tetralins, a secondary amino compound and a dichlorobenzene. It is a conjugate base of a sertraline(1+). It derives from a hydride of a tetralin.|Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.|Sertraline is a Serotonin Reuptake Inhibitor. The mechanism of action of sertraline is as a Serotonin Uptake Inhibitor, and Cytochrome P450 2D6 Inhibitor.|Sertraline is a selective serotonin reuptake inhibitor (SSRI) used in the therapy of depression, anxiety disorders and obsessive-compulsive disorder. Sertraline therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and has been linked to rare instances of clinically apparent acute liver injury.|A selective serotonin uptake inhibitor that is used in the treatment of depression.Basic Info-
Product Name:
Sertraline
Other Name:1-Naphthalenamine,4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-,(1S,4S)-;1-Naphthalenamine,4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-,(1S-cis)-;(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine;CP 51974;Sertraline;(+)-Sertraline;(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthaleneamine
CAS No.:79617-96-2
Molecular Formula:C17H17Cl2N
InChIKeys:InChIKey=VGKDLMBJGBXTGI-SJCJKPOMSA-N
Molecular Weight:306.23
Exact Mass:306.23
EC Number:616-708-3
UNII:QUC7NX6WMB
DSSTox ID:DTXSID6023577
ATC Code:N06AB06|N - Nervous system
Categories:
Characteristics-
PSA:
12
XLogP3:5.1
Appearance:Solid
Density:1.3±0.1 g/cm3
Melting Point:188-190 °C(lit.)
Boiling Point:416.3±45.0 °C at 760 mmHg
Flash Point:205.6±28.7 °C
Refractive Index:1.621
Water Solubility:H2O: 3.5mg/L
PKA:9.16None
Dissociation Constants:9.16
Collision Cross Section:167.3 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated]
Experimental Properties:MW: 342.70. Crystals, mp 243-245 °C. Specific optical rotation at 23 °C = +37.9 deg (c = 2 in methanol). Solubility at room temperature (mg/ml): water 3.8; 0.1N HCl 0.51; 0.1N NaOH 0.002; ethanol 15.7; isopropyl alcohol 4.3; chloroform 110; acetone 1.1; N,N-dimethylformamide 88; dimethylsulfoxide 147; ethyl acetate 0.20; acetonitrile 0.85; methanolic 0.1N HCl 47; chloroform/methanol (1:1) 134. pKa (ethanol:water, 1:1 v/v): 8.5. density = 1.37 /Sertraline hydrochloride/
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
D-Biotin,Tobramycin base,L(-)-Carnitine base,Polymyxin B sulfate USP,Kanamycin sulfate monohydrate,Finasteride 99% USP
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Location:
1613 Guangyin Building,No.42 E.Fengqi Road,Hangzhou,310012 China.
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Payment Terms:
TT against copy of documents,L/C
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Average lead Time:
7
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Total Annual Revenue:
$25 million-$50 million
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Total Employees:
11-50
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Year of Establishment:
2011
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Pakistan
Sertaline
20 KG Aug 30, 2024 Post an enquiry for this product