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21259-20-1

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CAS No.:

21259-20-1

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2022-08-07

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Guangzhou Yaoguang Technology Co., Ltd.

Company Type:

Manufactory

Location:

China

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Main Products:

Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides

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Description

21259-20-1

ECHEMI Editorial Reference

T-2 Toxin (T-2 Mycotoxin) is a toxic trichothecene mycotoxin produced by various Fusarium species in feedstuffs and cereal grains, LD50 values of T-2 Toxin in mice and rats are 5.2 and 1.5 mg/kg BWa,respectively [1]. T-2 Toxin (T-2 Mycotoxin) can be transformed into a variety of metabolite, the typical metabolites of T-2 toxin in animals are HT-2 toxin and T-2-triol, which are hydrolysates[1]. T-2 Toxin (T-2 Mycotoxin) is an inhibitor of protein synthesis resulting from binding peptidylt
T-2 toxin is a trichothecene mycotoxin produced by fungi of the genus Fusarium. It is a common contaminant in food and feedstuffs of cereal origin and is known to cause a range of toxic effects in humans and animals. It has a role as a mycotoxin, a cardiotoxic agent, a neurotoxin, an environmental contaminant, an apoptosis inducer, a DNA synthesis inhibitor and a fungal metabolite. It is a trichothecene, an acetate ester and an organic heterotetracyclic compound. It derives from a HT-2 toxin.|A potent mycotoxin produced in feedstuffs by several species of the genus FUSARIUM. It elicits a severe inflammatory reaction in animals and has teratogenic effects.

Basic Info

Product Name:

T 2 Toxin

Other Name:

Trichothec-9-ene-3,4,8,15-tetrol,12,13-epoxy-,4,15-diacetate 8-(3-methylbutanoate),(3α,4β,8α)-;Trichothec-9-ene-3α,4β,8α,15-tetrol,12,13-epoxy-,4,15-diacetate 8-isovalerate;Spiro[2,5-methano-1-benzoxepin-10,2′-oxirane],trichothec-9-ene-3,4,8,15-tetrol deriv.;8α-(3-Methylbutyryloxy)-4β,15-diacetoxyscirp-9-en-3α-ol;4β,15-Diacetoxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-en-3α-ol;T 2 Toxin;Fusariotoxin T 2;Toxin T 2;Insariotoxin;T 2 mycotoxin;NSC 138780;Mycotoxin T 2;T 2;T-2 Lienomycin;116163-69-0;9061-58-9;11051-21-1;22916-10-5;22916-18-3;25152-34-5;26400-47-5;27640-92-2;36653-66-4;60119-99-5;145427-93-6

CAS No.:

21259-20-1

Molecular Formula:

C24H34O9

InChIKeys:

InChIKey=BXFOFFBJRFZBQZ-WTHKCUGASA-N

Molecular Weight:

466.52

Exact Mass:

466.52

EC Number:

244-297-7

UNII:

I3FL5NM3MO

DSSTox ID:

DTXSID6021298

Color/Form:

White needles from benzene & Skellysolve B; acetate deriv: amorphous solid from ether & pentane|Crystals|White needles

HScode:

29329990

Categories:

Heterocyclic Compound

Characteristics

PSA:

121

XLogP3:

2.27 (est)

Appearance:

white powder

Density:

1.3±0.1 g/cm3

Melting Point:

151-152 °C

Boiling Point:

544.9±50.0 °C at 760 mmHg

Flash Point:

2 °C

Refractive Index:

1.547

Water Solubility:

Freely soluble in ethyl alcohol, ethyl acetate, chloroform, DMSO, and other organic solvents; slightly sol in petroleum ether; very slightly soluble in water.

Storage Conditions:

−20°C

Vapor Pressure:

3.06X10-11 mm Hg at 25 deg C (est)

Toxicity:

LD50 orally in female rats: 4.0 mg/kg (Marasas); LD50 (mg/kg) in mice: 5.2 i.p., 4.2 i.v.; in rats: 7.0 intragastric, 0.9-1.3 i.p., 0.9 i.v., 2.0 s.c.; in guinea pigs: 3.0-4.0 orally, 5.3 intragastric, 1.0 i.m., 1.0-2.0 i.v., 1.0-2.0 s.c.; in pigs: 5.0 orally, 3.0 i.v. (Yagen, Bailer)

Specific rotation:

D26 +15° (c = 2.58 in ethanol)

Henrys Law Constant:

Henry's Law constant = 5.45X10-19 atm-cu m/mole at 25 °C (est)

Collision Cross Section:

214 Å² [M+NH4]+ [CCS Type: TW, Method: calibrated with polyalanine]|212.51 Å² [M+Na]+

Experimental Properties:

Ester groups are saponified by alkalis, and the epoxide is opened by strong mineral acids|Colorless, mostly crystalline solids that have been well characterized by physical and spectroscopic techniques. ... require higher polarity solvents, such as aqueous methanol or aqueous acetonitrile. /Trichothecenes/|The trichothecenes are generally stable; for example, DON (deoxynivalenol) can be stored in organic solvents, such as ethyl acetate, for a long time without any significant deterioration ... They remain unaffected when refluxed with various organic solvents and also under mildly acidic conditions.

See More T 2 Toxin Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 1, Oral

Acute toxicity - Category 1, Dermal

Skin irritation, Category 2

Acute toxicity - Category 1, Inhalation

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H300 Fatal if swallowed H310 Fatal in contact with skin H315 Causes skin irritation H330 Fatal if inhaled
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P262 Do not get in eyes, on skin, or on clothing. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P316 Get emergency medical help immediately. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P320 Specific treatment is urgent (see ... on this label).
Storage	P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20 deg C Keep in a dry place.

See More T 2 Toxin Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides

Location:
Room 308-80, building 1, 1963 Huaguan Road, Tianhe District, Guangzhou

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,100% TT in advance

Average lead Time:
30

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2021

Guangzhou Yaoguang Technology Co., Ltd. is a high-tech enterprise specializing in the R&D, manufacturing, and custom synthesis of fine chemicals, whose management has many years of experience in fine chemicals.
The company has established a core technical team with professors, engineers, doctors, masters and undergraduates as the backbone power, and has equipped with advanced synthesis equipment, high-tech analytical instruments and mass production equipment, which can allow us to meet the requirements of customers. The company adheres to the operation philosophy of "Credit and Quality Come First". Taking advantage of combining production, study and research, it has established strategic partnership with many universities and key laboratories in China.
We are an ISO 9001-2015 certified enterprise, our products are widely used in life science, pharmaceutical science, biological science, materials, daily chemical, cosmetics, organic synthesis, catalyst, detection-analysis and other fields. The main products include biochemicals, organic intermediates, specialty chemicals, chemical reagents, custom-synthetic chemicals…etc., which can meet customers’ needs varying from gram level, kilogram level to ton level.
Through years of accumulation, BTO has 2 subsidiaries, 5 offices. Our products are sold to China, Europe, America, Japan, South Korea and other countries and regions, have been recognized and trusted by global customers.
Instrument and Equipment: multiple sets of lab/pilot scale test reaction equipment, freezing equipment, rectification equipment, dephlegmator, HPLC, GC, GC-MS, LC-MS, X-RAY, IR…etc.
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21259-20-1

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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