Dideoxyinosine
69655-05-6
99%
Bottle,barrel,cargo,container,etc.
2026-10-02
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Product Description
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Seller Information
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DescriptionKeywords
Dideoxyinosine
69655-05-6
C10H12N4O3
Quick DetailsProName:Dideoxyinosine
CasNo:69655-05-6
Molecular Formula:C10H12N4O3
Appearance:powder, or liquid
Application:Pharmaceuticals, intermediates, APIs, custom synthesis, chemicals
DeliveryTime:5-7 Days
PackAge:Bottle, barrel, cargo, container, etc.
Port:Shanghai
Purity:99
Storage:Stored in room temperature, ventilated place
Transportation:By air, ship, express, etc.
LimitNum:0
Grade:Industrial Grade
SuperiorityBest Seller, High Quality, Competitive Price, Fast Delivery, Quick Response
DetailsLEAPChem supplies high quality Pharmaceuticals, intermediates, APIs, custom synthesis, fine chemicals and other industrial chemicalsECHEMI Editorial ReferenceDidanosine(Videx) is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.Target: NRTIs; HIVDidanosine is a dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Didanosin
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite.
Didanosine is an orally active purine dideoxynucleoside analog indicated for adult and pediatric patients with advanced HIV infection who are either intolerant or significantly deteriorated on zidovudine. It appears to increase CD4 cell counts and decrease p24 antigen levels.Major adverse effects are pancreatitis, peripheral neuropathy and diarrhea.Unlike zidovudine, didanosine exhibits insignificant bone marrow suppression.
White Powder
ChEBI: A purine 2',3'-dideoxyribonucleoside that is inosine in which the hydroxy groups at both the 2' and the 3' positions on the sugar moiety have been replaced by hydrogen.Basic Info-
Product Name:
Dideoxyinosine
Other Name:bmy40900;ddino;nsc612049;2',3'-Dideoxy inosine(DDI);DDI, Didanosine;2.3-Dideoxy;2',3'-Dideoxy-D-inosine;DIDANOSINE / 2'',3''-DIDEOXYINOSINE
CAS No.:69655-05-6
Molecular Formula:C10H12N4O3
InChIKeys:BXZVVICBKDXVGW-NKWVEPMBSA-N
Molecular Weight:236.23
Exact Mass:236.23
BRN:3619529
EC Number:614-994-4
NSC Number:612049
Color/Form:White to Off-white
HScode:29335990
Categories:
Characteristics-
PSA:
88.7
XLogP3:-1.2
Appearance:White to Off-white Powder
Density:1.2917 (rough estimate)
Melting Point:193-195 °C
Boiling Point:193-195 C
Flash Point:275.0±32.9 °C
Refractive Index:-28 ° (C=0.34, H2O)
Water Solubility:1-5 g/100 mL at 21 ºC
Storage Conditions:2-8°C
Vapor Pressure:6.6 mm Hg @ 25 deg C /Estimated/
Specific rotation:D25 -26.3° (c = 10 in water)
PKA:9.12(at 25℃)
Air and Water Reactions:Water soluble.
Critical Temperature & Pressure:Inert atmosphere,Store in freezer, under -20°C
Hazard IdentificationClassification of the substance or mixture
Germ cell mutagenicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H341 Suspected of causing genetic defects
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals
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Location:
Room A, 23rd Floor, No. 609 Yan'an Road, Gongshu District, Hangzhou, Zhejiang
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Payment Terms:
TT against copy of documents,D/P,L/C
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Average lead Time:
5
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Total Annual Revenue:
Above $100 million
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Year of Establishment:
2020
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Certifications:
ISO
">Company ProfileLEAPChem is a specialized fine chemical supplier for research, development and production.
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Our client list includes many major pharmaceutical and science companies, universities, research institutions and chemical catalogue companies.
Methodology: Sound & Stable; Active & Innovative.
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Goals: Customer's Satisfaction
We regard client's success as our success.
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To achieve this strategic vision, we always push ourselves to exceed our customer's requirement. By focusing on the aim of 'Beyond Your Expectation', we continually expand our product lines, and enhance our systematic management and human resources.
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