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Ciproxifan

Unit Price: Get Latest Price
CAS No.:

184025-19-2

Content:

0.99%

Price valid (until):

2026-07-10

Company Type:
Manufactory
Location:
United States
Qualification:
Main Products:

Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

  • Product Description

  • Seller Information

  • Description
    ProductNameCiproxifan
    Cat NoCEI-0214
    DescriptionCiproxifan can potently inhibit H3-receptor with IC50 of 9.2 nM.
    CAS No184025-19-2
    Molecular Weight386.4
    Purity0.99
    Storage2 years -20centigrade Powder
    TargetsH3-receptor
    Molecular FormulaC16H18N2O2.C4H4O4
    Chemical Namecyclopropyl-(4-(3-1H-imidazol-4-yl)propyloxy) phenyl) ketone
    SolubilityDMSO 54 mg/ml, Water 1 mg/ml, Ethanol 54 mg/ml
    In vitroCiproxifan is a novel chemical series of histamine H3-receptor antagonist.Ciproxifan can potently inhibit H3-receptor with IC50 of 9.2 nM. In vitro, ciproxifan is a competitive antagonist at the H3 autoreceptor controlling [3H]histamine release from synaptosomes and displayed similar Ki values (0.5-1.9 nM) at the H3 receptor controlling the electrically-induced contraction of guinea pig ileum or at the brain H3 receptor labeled with [125I]iodoproxyfan. Ciproxifan displayed at least 3-orders of magnitude lower potency at various aminergic receptors studied in functional or binding tests.
    categorySpecialty Chemicals(c26)
    cas_num184025-19-2

    Basic Info
    Product Name:

    CIPROXIFAN

    Other Name:

    Ciproxifan Moleate;FUB 359 Maleate;FUB359 Maleate;FUB-359 Maleate;Cyclopropyl (4-[3-(1H-imidazol-4-yl)propyloxy]phenyl) ketone maleate salt;Ciproxifan maleate, >=98%;(4-(3-(1H-Imidazol-5-yl)propoxy)phenyl)(cyclopropyl)methanone maleate;CIPROXIFAN

    CAS No.:

    184025-19-2

    Molecular Formula:

    C16H18N2O2.C4H4O4

    InChIKeys:

    RLQFKEYRALXXEJ-BTJKTKAUSA-N

    Molecular Weight:

    386.402

    Exact Mass:

    386.147797

    DSSTox ID:

    DTXSID20585107

    Categories:

    Characteristics
    PSA:

    129.58000

    XLogP3:

    2.72580

    Appearance:

    white to beige

    Boiling Point:

    743.6ºC at 760 mmHg

    Flash Point:

    403.5ºC

    Water Solubility:

    DMSO: soluble32mg/mL

    Vapor Pressure:

    3.22E-23mmHg at 25°C

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Skin irritation, Category 2

    Skin sensitization, Category 1

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    H315 Causes skin irritation

    H317 May cause an allergic skin reaction

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P272 Contaminated work clothing should not be allowed out of the workplace.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P333+P317 If skin irritation or rash occurs: Get medical help.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

    Location:

    Shirley, New York 11967, USA

    Payment Terms:

    TT against copy of documents,D/P

    Average lead Time:

    15

    Total Annual Revenue:

    $1 million-$2.5 million

    Year of Establishment:

    2004

    Creative Enzymes is a leading Manufactory supplier of Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- based in America. With a commitment to quality and customer satisfaction, Creative Enzymes has become a trusted name in the industry. Our product line includes a range of high-quality Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-, which are available at competitive prices. Creative Enzymes has established itself as a reliable supplier of chemical products on the echemi.com.

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