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6BIO

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CAS No.:

667463-62-9

Content:

98%

Price valid (until):

2026-08-08

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Creative Enzymes

Company Type:

Manufactory

Location:

United States

Qualification:

Main Products:

Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

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Product Description
Seller Information
Inquiry History

Description

ProductName	6BIO
Cat No	CEI-0951
Description	Scientific Background Potent and selective inhibitor of glycogen synthase kinase-3 (GSK-3) IC50=5 nM. The first pharmacological agent shown to maintain self-renewal in human and mouse embryonic stem cells. Promotes proliferation in mammalian cardiomyocytes. A potent inhibitor of malignant lymphoid cell proliferation.
Abbr	6BIO(GSK3)
Alias	(2'Z, 3'E)-6-Bromoindirubin-3'-oxime
Appearance	Purple powder
Product Overview	GSK3 inhibitor
CAS No	667463-62-9
Molecular Weight	356.2
Purity	98% (TLC: 5% CH3OH3 in CH2Cl2, Rf=0.43); NMR (Conforms)
Synonyms	(2'Z,3'E)-6-Bromoindirubin-3'-oxime
Targets	GSK3
Molecular Formula	C16H10BrN3O2
Melting Point	263-265ºC
Solubility	Soluble in DMSO (15 mg/ml); or Ethanol (4 mg/ml, warm)
category	Inhibitors(c1514)
cas_num	667463-62-9

Basic Info

Product Name:

6-Bromoindirubin-3′-oxime

Other Name:

2H-Indol-2-one,6-bromo-3-[(3E)-1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-,(3Z)-;(3Z)-6-Bromo-3-[(3E)-1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one;(2′Z,3′E)-6-Bromoindirubin-3′-oxime;GSK 3 Inhibitor IX;GSK 3 IX;MLS 2052;BIO;6-Bromoindirubin-3′-oxime;6-BIO;KIN 001-043;(2Z,3E)-6′-Bromo-3-(hydroxyimino)-[2,3′-biindolinyliden]-2′-one

CAS No.:

667463-62-9

Molecular Formula:

C16H10BrN3O2

InChIKeys:

InChIKey=DDLZLOKCJHBUHD-WAVHTBQISA-N

Molecular Weight:

356.178

Exact Mass:

356.17

NSC Number:

745931|737347

DSSTox ID:

DTXSID60648023

HScode:

29339900

Categories:

Inhibitors

Characteristics

PSA:

81.2 Å²

Appearance:

dark red solid

Density:

1.8±0.1 g/cm3

Melting Point:

>300 °C

Boiling Point:

554.3°C at 760 mmHg

Flash Point:

289.0±30.1 °C

Refractive Index:

1.802

Water Solubility:

DMSO: >5 mg/mL

Storage Conditions:

2-8°C

See More 6-Bromoindirubin-3′-oxime Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 6-Bromoindirubin-3′-oxime Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

Location:
Shirley, New York 11967, USA

Payment Terms:
TT against copy of documents,D/P

Average lead Time:
15

Total Annual Revenue:
$1 million-$2.5 million

Year of Establishment:
2004

Creative Enzymes is a leading Manufactory supplier of Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- based in America. With a commitment to quality and customer satisfaction, Creative Enzymes has become a trusted name in the industry. Our product line includes a range of high-quality Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-, which are available at competitive prices. Creative Enzymes has established itself as a reliable supplier of chemical products on the echemi.com.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Greece	6-Bromoindirubin-3’-oxime	15 G	Jun 28, 2026

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