BAY 11-7082
19542-67-7
95%
2026-07-01
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName BAY 11-7082 Cat No CEI-0590 Description Potential anti-inflammatory agent. Selectively and irreversibly inhibits NF-κB activation by blocking TNF-α-induced phosphorylation of IκB-α without affecting constitutive IκB-α phosphorylation. Inhibits the TNF-α-induced surface expression of adhesion molecules ICAM-1, VCAM-1, and E-selectin in human endothelial cells with IC50 values of 5-10 µM. Appearance Colorless film Product Overview A NF-κB activation inhibitor CAS No 19542-67-7 Molecular Weight 622.84 Purity >95% by HPLC Storage -20 centigrade Targets NFKB1 Molecular Formula C₁₀H₉NO₂S Chemical Name (E)-3-(4-Methylphenylsulfonyl)-2-propenenenitrile Solubility DMSO Shipping Conditions Gel pack category Inhibitors(c1514) cas_num 19542-67-7 Basic Info-
Product Name:
(2E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile
Other Name:2-Propenenitrile,3-[(4-methylphenyl)sulfonyl]-,(2E)-;Acrylonitrile,3-(p-tolylsulfonyl)-,(E)-;2-Propenenitrile,3-[(4-methylphenyl)sulfonyl]-,(E)-;(2E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile;BAY 117821;BAY 11-7082;BAY 11-7821
CAS No.:19542-67-7
Molecular Formula:C10H9NO2S
InChIKeys:InChIKey=DOEWDSDBFRHVAP-KRXBUXKQSA-N
Molecular Weight:207.25
Exact Mass:207.25
Categories:
Characteristics-
PSA:
66.3
XLogP3:1.4
Appearance:white solid
Density:1.237±0.06 g/cm3(Predicted)
Melting Point:132-133 °C
Boiling Point:397.6±42.0 °C(Predicted)
Flash Point:194.3±27.9 °C
Refractive Index:1.557
Water Solubility:DMSO: 25 mg/mL, soluble
Storage Conditions:Store at +4°C
Vapor Pressure:1.57E-06mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product