Limonin
1 Inquiries
1180-71-8
2026-07-02
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName Limonin Cat No CEI-1398 Product Overview Limonin is a chemically-induced carcinogenesis inhibitor and HIV-1 replication inhibitor. The human immunodeficiency virus (HIV) is a lentivirus that causes the acquired immunodeficiency syndrome (AIDS). When culturing the HIV-1 in human peripheral blood mononuclear cells (PBMC) and monocytes/macrophages (M/M), Limonin inhibit the HIV-1 replication in all cellular systems and inhibit HIV-1 replication with EC50 value of 60u μM in PBMC cells in a dose-dependent way. In human hepatoma HepG2 cells, limonin can induced apoptosis, which was evidenced by WB analysis of some apoptosis factors. In the female Syrian hamsters treated with DMBA, which can cause tumor, limonin showed a 60% reduction in tumor burden. It decreased 20% tumor number and 50% tumor mass. In male F344 rats treated with azoxymethane (AOM), 0.05% limonin in diet significantly reduced (65%-92% inhibition) the incidence of colonic adenocarcinoma. Thus, limonin has chemopreventive effects on chemically induced carcinogenesis. CAS No 1180-71-8 Molecular Weight 470.51 Storage Store at -20°C Synonyms Limonoic acid 3,19:16,17 dilactone Targets HIV-1 Molecular Formula C26H30O8 Chemical Name 12-(furan-3-yl)-6,6,8a,12a-tetramethyldecahydrooxireno[2,3-d]pyrano[4,3:3,3a]isobenzofuro[5,4-f]isochromene-3,8,10(1H,6H,8aH)-trione Solubility Soluble in DMSO > 10 mM Shipping Conditions Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request category Biosynthetic Natural Products(c1523) cas_num 1180-71-8 Basic Info-
Product Name:
Limonin
Other Name:11H,13H-Oxireno[d]pyrano[4′,3′:3,3a]isobenzofuro[5,4-f][2]benzopyran-4,6,13(2H,5aH)-trione,8-(3-furanyl)decahydro-2,2,4a,8a-tetramethyl-,(2aR,4aR,4bR,5aS,8S,8aS,10aR,10bR,14aS)-;11H,13H-Oxireno[d]pyrano[4′,3′:3,3a]isobenzofuro[5,4-f][2]benzopyran-4,6,13(2H,5aH)-trione,8-(3-furyl)decahydro-2,2,4a,8a-tetramethyl-;Limonin;Limonoic acid,di-δ-lactone;(2aR,4aR,4bR,5aS,8S,8aS,10aR,10bR,14aS)-8-(3-Furanyl)decahydro-2,2,4a,8a-tetramethyl-11H,13H-oxireno[d]pyrano[4′,3′:3,3a]isobenzofuro[5,4-f][2]benzopyran-4,6,13(2H,5aH)-trione;Citrolimonin;Dictamnolactone;Evodin;11H,13H-Oxireno[d]pyrano[4′,3′:3,3a]isobenzofuro[5,4-f][2]benzopyran-4,6,13(2H,5aH)-trione,8-(3-furanyl)decahydro-2,2,4a,8a-tetramethyl-,[2aR-(2aα,4aβ,4bR*,5aα,8α,8aα,10aα,10bR*,14aα)]-;Obaculactone;Limonine;7,16-Dioxo-7,16-dideoxylimondiol;Obakulactone;1392-24-1
CAS No.:1180-71-8
Molecular Formula:C26H30O8
InChIKeys:InChIKey=KBDSLGBFQAGHBE-MSGMIQHVSA-N
Molecular Weight:470.51
Exact Mass:470.51
UNII:L0F260866S
DSSTox ID:DTXSID8045985
HScode:29321900
Categories:
Characteristics-
PSA:
105
XLogP3:1.8
Appearance:White to slightly off white powder
Density:1.39±0.1 g/cm3(Predicted)
Melting Point:298 °C
Boiling Point:67 °C
Flash Point:358.0±31.5 °C
Refractive Index:1.602
Storage Conditions:2-8°C
Vapor Pressure:9.96E-18mmHg at 25°C
Specific rotation:D -128° (c = 1.21 in acetone)
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
India
Limonin
2 G Dec 27, 2024 Post an enquiry for this product