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GSK-25

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CAS No.:

874119-56-9

Content:

95%

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2026-07-13

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Creative Enzymes

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Manufactory

Location:

United States

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Main Products:

Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

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Description

ProductName	GSK-25
Cat No	CEI-1127
Description	GSK-25 has promising oral bioavailability (49% in rat and 19% in monkey) a good half-life (1.8h in rat and 2.2h in monkey) and maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50=398nM, p70S6K IC50=1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).
Abbr	GSK-25(RPS6KA1, RPS6KB1)
Alias	RP11-492M19.2, HU-1, MAPKAPK1A, RSK, RSK1
CAS No	874119-56-9
Molecular Weight	513.33
Purity	> 95%
Stability	2 years -20 centigrade Powder1 month -4 centigrade in DMSOMore than one month -80 centigrade in DMSO
Storage	4 centigrade
Synonyms	RP11-492M19.2, HU-1, MAPKAPK1A, RSK, RSK1
Targets	RSK1, p70S6K
IC50	398nM， 1000nM
Molecular Formula	C24H16Cl2F2N6O
Chemical Name	4-(4-chloro-2-fluorophenyl)-2-(2-chloropyridin-4-yl)-N-(6-fluoro-1H-indazol-5-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide
Solubility	DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
category	Specialty Chemicals(c26)
cas_num	874119-56-9

Basic Info

Product Name:

4-(4-Chloro-2-fluorophenyl)-2-(2-chloropyridin-4-yl)-N-(6-fluoro-1H-indazol-5-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide

Other Name:

GSK-25;874119-56-9;4-(4-chloro-2-fluorophenyl)-2-(2-chloropyridin-4-yl)-N-(6-fluoro-1H-indazol-5-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide;Dihydropyrimidine, 25;C24H16Cl2F2N6O;CHEMBL521347;GSK25;GSK 25;SCHEMBL4932798;BDBM25496;SYN1124

CAS No.:

874119-56-9

Molecular Formula:

C24H16Cl2F2N6O

InChIKeys:

KZYAHEIPPAPADQ-UHFFFAOYSA-N

Molecular Weight:

513.3

Exact Mass:

512.0730709

Categories:

Characteristics

Seller Information

Business Type:
Manufactory

Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

Location:
Shirley, New York 11967, USA

Payment Terms:
TT against copy of documents,D/P

Average lead Time:
15

Total Annual Revenue:
$1 million-$2.5 million

Year of Establishment:
2004

Creative Enzymes is a leading Manufactory supplier of Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- based in America. With a commitment to quality and customer satisfaction, Creative Enzymes has become a trusted name in the industry. Our product line includes a range of high-quality Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-, which are available at competitive prices. Creative Enzymes has established itself as a reliable supplier of chemical products on the echemi.com.
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GSK-25

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