Company Type:
Manufactory
Location:
United States
Qualification:
Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName caspase-1 Cat No EXWM-4211 Description From mammalian monocytes. This enzyme is part of the family of inflammatory caspases, which also includes caspase-4 (EC 3.4.22.57) and caspase-5 (EC 3.4.22.58) in humans and caspase-11 (EC 3.4.22.64), caspase-12, caspase-13 and caspase-14 in mice. Contains a caspase-recruitment domain (CARD) in its N-terminal prodomain, which plays a role in procaspase activation. Cleaves pro-interleukin-1β (pro-IL-1β) to form mature IL-1β, a potent mediator of inflammation. Also activates the proinflammatory cytokine, IL-18, which is also known as interferon-γ-inducing factor. Inhibited by Ac-Tyr-Val-Ala-Asp-CHO. Caspase-11 plays a critical role in the activation of caspase-1 in mice, whereas caspase-4 enhances its activation in humans. Belongs in peptidase family C14. Form Liquid or lyophilized powder Enzyme Commission Number EC 3.4.22.36 CAS No 122191-40-6 Storage Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC. Synonyms interleukin 1β-converting enzyme; protease VII; protease A; interleukin 1β precursor proteinase; interleukin 1 converting enzyme; interleukin 1β-converting endopeptidase; interleukin-1β convertase; interleukin-1β converting enzyme; interleukin-1β precursor proteinase; prointerleukin 1β protease; precursor interleukin-1β converting enzyme; pro-interleukin 1β proteinase; ICE Reaction Strict requirement for an Asp residue at position P1 and has a preferred cleavage sequence of Tyr-Val-Ala-Asp┼ Notes This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. category Specialty Chemicals(c26) cas_num 122191-40-6 Basic Info-
Product Name:
CASPASE-1
Other Name:ICE;ICE 1B HUMAN;IL-1BETA CONVERTING ENZYME;INTERLEUKIN-1BETA CONVERTING ENZYME;INTERLEUKIN-1B-CONVERTING ENZYME HUMAN;CASPASE-1 PROTEIN, RECOMBINANT HUMAN ACTIVE;CASPASE 1 HUMAN;CASPASE-1 HUMAN, RECOMBINANT, ACTIVE
CAS No.:122191-40-6
Molecular Formula:C27H35N6O9+
InChIKeys:ZPJLFPYLVYCKSO-RJCMWMPSSA-O
Molecular Weight:587.6
Exact Mass:587.246552
Categories:
Characteristics-
PSA:
240
Storage Conditions:−70°C
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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