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11-Hydroxy-9-methyl-3-oxatricyclo[5.3.1.04,11]undec-1(10)-en-2-one
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Galiellalactone
Galiellalactone
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CAS No.:
133613-71-5
Content:
95%
Price valid (until):
2026-08-18
Company Type:
Manufactory
Location:
United States
Qualification:
Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Galiellalactone Cat No CEI-1604 Description Galiellalactone is a fungal metabolite isolated from the ascomycetes G. rufa strain A75-86 and A111-95 that inhibits IL-6-mediated JAK/STAT signal transduction in HepG2 cells with an IC50 value of 0.25-0.5 μM. The selectivity of this compound is achieved by its ability to block the binding of activated STAT3 dimers to their DNA binding sites without affecting phosphorylation of the STAT3 transcription factor. At 10-50 μM, galiellalactone exhibits dose-dependent growth inhibitory effects on prostate cancer stem cell-like cells expressing active STAT3, suggesting it may be a useful therapeutic approach to control JAK/STAT signaling. Form A white lyophilized powder CAS No 133613-71-5 Molecular Weight 194.2 Purity >=95% Stability 2 years when stored properly Storage Store at -20° C Molecular Formula C11H14O3 Chemical Name (7bS)-5,5aR,6,7,7aR,7b-hexahydro-7b-hydroxy-4S-methyl-indeno[1,7-bc]furan-2(4H)-one Formulation In Phosphate buffer saline (pH 7.4) containing 20% glycerol 1mM DTT. category Specialty Chemicals(c26) cas_num 133613-71-5 Basic Info-
Product Name:
11-Hydroxy-9-methyl-3-oxatricyclo[5.3.1.04,11]undec-1(10)-en-2-one
Other Name:Galiellalactone;133613-71-5;11-Hydroxy-9-methyl-3-oxatricyclo[5.3.1.04,11]undec-1(10)-en-2-one;(4R,7R,9S,11S)-11-Hydroxy-9-methyl-3-oxatricyclo[5.3.1.04,11]undec-1(10)-en-2-one;SCHEMBL20588839;DTXSID90395194;AKOS025294321;J-006418
CAS No.:133613-71-5
Molecular Formula:C11H14O3
InChIKeys:SOIISBQQYAGDKM-UHFFFAOYSA-N
Molecular Weight:194.23
Exact Mass:194.094294304
DSSTox ID:DTXSID90395194
Categories:
Characteristics -
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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