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Indomethacin

ISO 11 Inquiries

Unit Price: Get Latest Price
CAS No.:

53-86-1

Grade:

Industrial Grade

Content:

99%

Packaging:

25kg

Price valid (until):

2023-03-31

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Flavors & Fragrances,Catalyst & Auxiliary,Intermediates,Dyes & Pigments,Inorganic Chemistry,petro chemicals

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Basic Information

    Product Name

    Indomethacin

    Multiple names

    Indomethacin Methanol Solution;
     Indomethacin Crystalline;
     Indomethacin Usp;
     Indometacin;
    1-(4-Chlorobenzoyl)-5-Methoxy-2-Methylindol-3-Ylacetic Acid;
     {1-[(4-Chlorophenyl)Carbonyl]-5-Methoxy-2-Methyl-1H-Indol-3-Yl}Acetate

    CAS No.

    53-86-1

    EC No.

    200-186-5

    MF No.

    C19H16ClNO4

    MW No.

    357.7802

     

    Product Usage

    As a pharmaceutical intermediate, it has obvious antipyretic effect.

     

    Specification

    Assay Item

    Standard

    Form

    White to off-white powder

    Color

    White to Light yellow to Light orange

    Acidity Coefficient (pKa)

    4.5(at 25℃)

    Melting Point

    158-162 °C

    Refractive Index

    1.6800 (estimate)

    density

    1.2135 (rough estimate)

     


    Certificates

    Basic Info
    Product Name:

    Indomethacin

    Other Name:

    1H-Indole-3-acetic acid,1-(4-chlorobenzoyl)-5-methoxy-2-methyl-;Indole-3-acetic acid,1-(p-chlorobenzoyl)-5-methoxy-2-methyl-;1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid;Amuno;1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid;1-(p-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid;α-[1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl]acetic acid;Indocid;Indocin;Indometacin;Indomethacin;Indomethacine;Metindol;N-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid;1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetic acid;Artrinovo;Artrivia;Confortid;Idomethine;Inacid;Indomed;Indomee;Infrocin;Mezolin;Methazine;Indacin;1-(4-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid;Indomecol;Metacen;Metartril;Dolovin;Indo-Rectolmin;Reumacide;Sadoreum;1-(4-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid;Indometacine;1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid;Indren;Inteban;Chrono-Indocid 75;Dolcidium PL;Bonidon Gel;Imbrilon;Indomod;Indo-Phlogont;Indo-Tablinen;Dolcidium;Bonidin;Mobilan;Indomethine;Inflazon;Elmetacin;Indoxen;Vonum;Tannex;Durametacin;Indoptic;Argun;Mikametan;Catlep;Indoptol;Chrono-Indicid;Lausit;Rheumacin LA;Inteban SP;Chibro-Amuno;Artracin;Indorektal;Indocid (pharmaceutical);Innamit;Indonol;[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid;Vital Vitacid;IndoRich;Flam;Globa;NSC 77541;Indocollyre;Endol;37242-43-6;91853-74-6;503560-73-4

    CAS No.:

    53-86-1

    Molecular Formula:

    C19H16ClNO4

    InChIKeys:

    InChIKey=CGIGDMFJXJATDK-UHFFFAOYSA-N

    Molecular Weight:

    357.79

    Exact Mass:

    357.79

    EC Number:

    200-186-5

    HScode:

    29339900

    Characteristics
    PSA:

    68.5

    XLogP3:

    3.4

    Appearance:

    Crystals. (NTP, 1992)

    Density:

    1.38 g/cm3

    Melting Point:

    158 °C

    Boiling Point:

    499.4ºC at 760 mmHg

    Flash Point:

    255.8ºC

    Water Solubility:

    soluble in acetone (40 mg/mL - clear, yellow solution), ethanol (20 mg/mL), ether, castor oil; soluble in chloroform (50 mg/mL - clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.ethanol: 50 mg/mL, clear, yellow-green

    Storage Conditions:

    Store at RT

    Vapor Pressure:

    9.89X10-11 mm Hg at 25 deg C (est)

    Toxicity:

    Oral-Rat  LD50 2.42  mg/kg; Oral-Mouse LD50: 11.84 mg/kg

    Flammability characteristics:

    Open flame is flammable; high heat decomposes toxic chloride and nitrogen oxide gas

    Odor:

    Odorless, or has slight odor

    Taste:

    Slight, bitter

    PKA:

    4.5None

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 2, Oral

    Skin sensitization, Category 1

    Reproductive toxicity, Category 1B

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H300 Fatal if swallowed

    H317 May cause an allergic skin reaction

    H360 May damage fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P272 Contaminated work clothing should not be allowed out of the workplace.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P203 Obtain, read and follow all safety instructions before use.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P333+P317 If skin irritation or rash occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Flavors & Fragrances,Catalyst & Auxiliary,Intermediates,Dyes & Pigments,Inorganic Chemistry,petro chemicals

    Location:

    17th Yuanlin Road ,Chongchuan area ,Nantong city ,Jiangsu province ,China

    Payment Terms:

    L/C,100% TT in advance

    Average lead Time:

    2

    Total Annual Revenue:

    Above $100 million

    Total Employees:

    201-300

    Year of Establishment:

    2008

    Certifications:

    GB/T19001-2016 / Iso9001:2015

    Established in 2008, running 14 years in Chemicals,

    with over one hundred staff ,selling thousand items, over RMB 1billion turnover annually.

    Regist ISO9001(No:31622Q10628ROM)
    Especially in the research, development and production of : Chemical raw materials,fine chemicals,pharmaceutical intermediates,Agrochemicals,food additives,Electronic chemicals,Environmental protection and water treatment...etc.
    We specialize in these field with the strength of good quality, pretty competitive price,and good service.

  • Inquiry History
    11 Inquiries
    Country Product Purchase Quantity Date Posted
    Canada

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    India

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