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Alectinib 99.5% buy - large image1
Alectinib 99.5% buy - image1

Alectinib 99.5%

Unit Price: Get Latest Price
CAS No.:

1256580-46-7

Content:

99.5%

Packaging:

custom

Price valid (until):

2023-04-07

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Plinabulin,Bromfenac sodium,Acotiamide,BI6727

  • Product Description

  • Seller Information

  • Description


      Product Detail  


    SECTION 1: Identification

    1.1GHS Product identifier

    Product name

    9-ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrile

    1.2Other means of identification

    Product number

    -

    Other names

    Alectinib;Alectinib;9-ethyl-6,11-dihydro-6,6-dimethyl-8-(4-(4-morpholinyl)-1-piperidinyl)-11-oxo-5h-benzo(b)carbazole-3-carbonitrile

    1.3Recommended use of the chemical and restrictions on use

    Identified uses

    Industrial and scientific research use.

    Uses advised against

    no data available

    1.4Supplier's details

    Company

    Maydy Biotechnology Co., Ltd.

    Address

    No.118, No.119, No.120, Area A, Headquarters Economic Industrial Park, Higher Vocational Park, No. 12 Chengxin Road, Gaochun District, Nanjing, Jiangsu Province, China

    Mobile

    86-18251822644

    1.5Emergency phone number

    Emergency phone number

    86-19941775929

    Service hours

    Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).


    SECTION 2: Hazard identification

    2.1Classification of the substance or mixture

    Not classified.

    2.2GHS label elements, including precautionary statements

    Pictogram(s)No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    2.3Other hazards which do not result in classification

    no data available

    SECTION 3: Composition/information on ingredients

    3.1Substances

    Chemical nameCommon names and synonymsCAS numberEC numberConcentration
    9-ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrile9-ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrile1256580-46-7-100%

    SECTION 4: First-aid measures

    4.1Description of necessary first-aid measures

    If inhaled

    Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

    Following skin contact

    Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

    Following eye contact

    Rinse with pure water for at least 15 minutes. Consult a doctor.

    Following ingestion

    Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

    4.2Most important symptoms/effects, acute and delayed

    no data available

    4.3Indication of immediate medical attention and special treatment needed, if necessary

    no data available

    SECTION 5: Fire-fighting measures

    5.1Suitable extinguishing media

    Use dry chemical, carbon dioxide or alcohol-resistant foam.

    5.2Specific hazards arising from the chemical

    no data available

    5.3Special protective actions for fire-fighters

    Wear self-contained breathing apparatus for firefighting if necessary.

    SECTION 6: Accidental release measures

    6.1Personal precautions, protective equipment and emergency procedures

    Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.

    6.2Environmental precautions

    Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.

    6.3Methods and materials for containment and cleaning up

    Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

    SECTION 7: Handling and storage

    7.1Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    7.2Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

    SECTION 8: Exposure controls/personal protection

    8.1Control parameters

    Occupational Exposure limit values

    no data available

    Biological limit values

    no data available

    8.2Appropriate engineering controls

    Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

    8.3Individual protection measures, such as personal protective equipment (PPE)

    Eye/face protection

    Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).

    Skin protection

    Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

    Respiratory protection

    If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.

    Thermal hazards

    no data available

    SECTION 9: Physical and chemical properties and safety characteristics

    Physical state

    no data available

    Colour

    no data available

    Odour

    no data available

    Melting point/freezing point

    no data available

    Boiling point or initial boiling point and boiling range

    no data available

    Flammability

    no data available

    Lower and upper explosion limit/flammability limit

    no data available

    Flash point

    no data available

    Auto-ignition temperature

    no data available

    Decomposition temperature

    no data available

    pH

    no data available

    Kinematic viscosity

    no data available

    Solubility

    no data available

    Partition coefficient n-octanol/water

    no data available

    Vapour pressure

    no data available

    Density and/or relative density

    1.28

    Relative vapour density

    no data available

    Particle characteristics

    no data available

    SECTION 10: Stability and reactivity

    10.1Reactivity

    no data available

    10.2Chemical stability

    no data available

    10.3Possibility of hazardous reactions

    no data available

    10.4Conditions to avoid

    no data available

    10.5Incompatible materials

    no data available

    10.6Hazardous decomposition products

    no data available

    SECTION 11: Toxicological information

    Acute toxicity

    • Oral: no data available
    • Inhalation: no data available
    • Dermal: no data available

    Skin corrosion/irritation

    no data available

    Serious eye damage/irritation

    no data available

    Respiratory or skin sensitization

    no data available

    Germ cell mutagenicity

    no data available

    Carcinogenicity

    no data available

    Reproductive toxicity

    no data available

    STOT-single exposure

    no data available

    STOT-repeated exposure

    no data available

    Aspiration hazard

    no data available

    SECTION 12: Ecological information

    12.1Toxicity

    • Toxicity to fish: no data available
    • Toxicity to daphnia and other aquatic invertebrates: no data available
    • Toxicity to algae: no data available
    • Toxicity to microorganisms: no data available

    12.2Persistence and degradability

    no data available

    12.3Bioaccumulative potential

    no data available

    12.4Mobility in soil

    no data available

    12.5Other adverse effects

    no data available

    SECTION 13: Disposal considerations

    13.1Disposal methods

    Product

    The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

    Contaminated packaging

    Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

    SECTION 14: Transport information

    14.1UN Number

    ADR/RID: no data availableIMDG: no data availableIATA: no data available

    14.2UN Proper Shipping Name

    ADR/RID: no data availableIMDG: no data availableIATA: no data available

    14.3Transport hazard class(es)

    ADR/RID: no data availableIMDG: no data availableIATA: no data available

    14.4Packing group, if applicable

    ADR/RID: no data availableIMDG: no data availableIATA: no data available

    14.5Environmental hazards

    ADR/RID: NoIMDG: NoIATA: No

    14.6Special precautions for user

    no data available

    14.7Transport in bulk according to IMO instruments

    no data available

    SECTION 15: Regulatory information

    15.1Safety, health and environmental regulations specific for the product in question

    Chemical nameCommon names and synonymsCAS numberEC number
    9-ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrile9-ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrile1256580-46-7-
    European Inventory of Existing Commercial Chemical Substances (EINECS)Not Listed.
    EC InventoryNot Listed.
    United States Toxic Substances Control Act (TSCA) InventoryNot Listed.
    China Catalog of Hazardous chemicals 2015Not Listed.
    New Zealand Inventory of Chemicals (NZIoC)Not Listed.
    Philippines Inventory of Chemicals and Chemical Substances (PICCS)Not Listed.
    Vietnam National Chemical InventoryNot Listed.
    Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)Not Listed.
    Korea Existing Chemicals List (KECL)Not Listed.

    SECTION 16: Other information

    Information on revision

    Creation DateJuly 15, 2019
    Revision DateJuly 15, 2019

    Abbreviations and acronyms

    • CAS: Chemical Abstracts Service
    • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
    • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
    • IMDG: International Maritime Dangerous Goods
    • IATA: International Air Transportation Association
    • TWA: Time Weighted Average
    • STEL: Short term exposure limit
    • LC50: Lethal Concentration 50%
    • LD50: Lethal Dose 50%
    • EC50: Effective Concentration 50%

    References

    ItemsSpecifications
    AppearanceWhite or of- white powder or crystlline power,odorless
    SolubilityVery soluble in N,N-Dimethylformamide,Soluble in methanol,Sparingly soluble inglacial acetic acid, Very slightly soluble inchloroform, Practically insoluble in water.
    Melting Point152°C~156°C

    Basic Info
    Product Name:

    Alectinib

    Other Name:

    5H-Benzo[b]carbazole-3-carbonitrile,9-ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-;9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile;AF 802;CH 5424802;Alectinib;CH 542480210;RG 7853;RG7853;RG-7853;Alecensa free base;1416163-60-4

    CAS No.:

    1256580-46-7

    Molecular Formula:

    C30H34N4O2

    InChIKeys:

    InChIKey=KDGFLJKFZUIJMX-UHFFFAOYSA-N

    Molecular Weight:

    483

    Exact Mass:

    482.62

    EC Number:

    1592732-453-0

    Categories:

    Antineoplastics

    Characteristics
    PSA:

    72.4

    XLogP3:

    5.2

    Density:

    1.3±0.1 g/cm3

    Flash Point:

    390.7±32.9 °C

    Refractive Index:

    1.673

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Plinabulin,Bromfenac sodium,Acotiamide,BI6727

    Location:

    No. 118, No. 119, No. 120, Area A, Headquarters Economic Industrial Park, Higher Vocational Park, No. 12 Chengxin Road, Gaochun District, Nanjing, Jiangsu Province, China.

    Payment Terms:

    L/C,100% TT in advance

    Average lead Time:

    30

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    5-10

    Year of Establishment:

    2023

    Maydy Biotechnology Co., Ltd. is a high-tech service enterprise based on the synthesis of biopharmaceuticals and chemical drugs. The company is committed to the technological research and production of biopharmaceuticals and chemical drugs. Based on the global pharmaceutical market demand, it integrates the process development, pilot-scale production, commercial production and innovative drug research and development of key intermediates. Technical backbone members of the team have domestic and foreign large-scale pharmaceutical production, management experience.

    At present, the company has a R & D laboratory of 2000 square meters in Life & Science Industry Park ,Jiangning Dist, and equipped with a full set of pilot and pilot equipment, complete good testing and analysis platform, we will be the most cost-effective price for global customers to provide the best quality services.

  • Country Product Purchase Quantity Date Posted
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