1,2-Diphenylhydrazine

1,2-diphenylhydrazine appears as orange powder or a bright orange crystalline solid. (NTP, 1992)|WHITE-TO-YELLOW CRYSTALS.
1,2-diphenylhydrazine appears as orange powder or a bright orange crystalline solid. (NTP, 1992)|1,2-Diphenylhydrazine is a white solid. There is no information on what it smells like or whether it will burn. It does not dissolve easily in water, but when placed in water, it rapidly breaks down into other chemicals. These include the toxic chemicals benzidine and azobenzene. It does not evaporate easily but may be released to air when attached to dust particles. 1,2-Diphenylhydrazine is a man-made chemical that was used in the past to make benzidine which was used to make various fabric dyes. Benzidine dyes are no longer used in the United States, but may still be used in other countries. The only current use of 1,2-diphenylhydrazine in the United States is in the production of medicines to treat inflammation and a type of arthritis.|1,2-Diphenylhydrazine was used in the past to produce benzidine-based dyes. Currently, the only use for it in the United States is in the production of anti-inflammatory drugs. Limited information is available on the health effects of 1,2-diphenylhydrazine. No information is available on the acute (short-term), chronic (long-term), reproductive, developmental, or carcinogenic effects of 1,2-diphenylhydrazine in humans. In a National Cancer Institute (NCI) study, liver tumors were observed in both sexes of rats and female mice exposed to 1,2-diphenylhydrazine in their diet. EPA has classified 1,2-diphenylhydrazine as a Group B2, probable human carcinogen.|Hydrazobenzene is a colorless, crystalline compound that emits toxic fumes of nitrogen oxides when heated to decomposition. Hydrazobenzene has been used primarily in the dye manufacturing industry as the precursor of the dye intermediate benzidine and is also used as an intermediate in the manufacture of pharmaceuticals. Exposure to this substance irritates the skin, nose, throat and lungs and can eventually lead to liver, kidney and brain damage. Hydrazobenzene is reasonably anticipated to be a human carcinogen based on evidence of carcinogenicity in experimental animals. (NCI05)