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High quality manufacture Chlorotrimethylsilane CAS NO.75-77-4

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CAS No.:

75-77-4

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Durban

Brand:

Custom

Packaging:

As per customer requirement

Price valid (until):

2024-05-15

Company Type:
Distributor
Location:
South Africa
Qualification:
Main Products:

Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    1. Chlorotrimethylsilane (CAS No. 75-77-4): A Versatile Silane Compound for Chemical Synthesis

    Dive into the realm of chlorotrimethylsilane, a versatile organosilicon compound widely used in chemical synthesis and industrial applications. This description explores its molecular structure, reactivity, and diverse roles as a reagent, catalyst, and protective agent, highlighting its importance in organic chemistry and materials science.

    2. Chlorotrimethylsilane (75-77-4): Unraveling the Chemistry of Silicon

    Embark on a journey through the chemistry of silicon with chlorotrimethylsilane as your guide. From its silicon-carbon bonds to its reactions with nucleophiles and electrophiles, this description delves into the fundamental principles and synthetic methodologies that underpin chlorotrimethylsilane's role as a cornerstone in organosilicon chemistry.

    3. Chlorotrimethylsilane (CAS No. 75-77-4): A Key Player in Silicon-Based Materials

    Explore the diverse applications of chlorotrimethylsilane in the synthesis of silicon-based materials with tailored properties. From silicone polymers to organosilanes and silicon nanoparticles, this description highlights chlorotrimethylsilane's versatility and its indispensable role in shaping the landscape of modern materials science and engineering.

    4. Chlorotrimethylsilane (75-77-4): Building Blocks for Functionalized Silanes

    Discover how chlorotrimethylsilane serves as a foundational building block for the synthesis of functionalized silanes with diverse chemical functionalities. From alkoxysilanes to chlorosilanes and beyond, this description elucidates chlorotrimethylsilane's role in introducing functional groups and modulating the reactivity and properties of organosilicon compounds.

    5. Chlorotrimethylsilane (CAS No. 75-77-4): Redefining Synthetic Strategies in Organic Chemistry

    Navigate the synthetic landscape of organic chemistry with chlorotrimethylsilane as a versatile reagent and protecting group. From its applications in functional group transformations to its role in complex molecule synthesis, this description showcases chlorotrimethylsilane's utility in enabling efficient and strategic synthetic pathways towards diverse molecular targets.

    6. Chlorotrimethylsilane (75-77-4): Enabling Green Chemistry Solutions

    Explore chlorotrimethylsilane's contributions to green chemistry principles by facilitating atom-efficient synthetic routes and minimizing waste generation. From its role in mild and selective reactions to its compatibility with environmentally benign solvents, this description underscores chlorotrimethylsilane's potential to advance sustainable synthetic methodologies in chemical manufacturing.

    7. Chlorotrimethylsilane (CAS No. 75-77-4): Driving Innovations in Pharmaceutical Synthesis

    Discover how chlorotrimethylsilane catalyzes innovations in pharmaceutical synthesis by enabling the efficient construction of complex drug molecules. From its applications in protecting sensitive functional groups to its role in key bond-forming reactions, this description highlights chlorotrimethylsilane's significance in accelerating drug discovery and development efforts.

    8. Chlorotrimethylsilane (75-77-4): Enhancing Materials Performance Through Silane Modification

    Enter the realm of materials modification with chlorotrimethylsilane, a transformative agent that enhances the performance and functionality of diverse materials. From hydrophobic surface treatments to crosslinking polymers and modifying nanoparticles, this description explores chlorotrimethylsilane's role in tailoring materials properties for specific applications.

    9. Chlorotrimethylsilane (CAS No. 75-77-4): Advancing Silicon-Based Technologies

    Witness how chlorotrimethylsilane drives advancements in silicon-based technologies, from electronics to energy storage and beyond. This description delves into its applications in silicon wafer fabrication, semiconductor device manufacturing, and the development of next-generation materials for renewable energy technologies, highlighting its indispensable role in technological innovation.

    10. Chlorotrimethylsilane (75-77-4): Exploring Frontiers in Silicon Chemistry

    Peer into the frontier of silicon chemistry with chlorotrimethylsilane as a catalyst for exploration and discovery. From its role in fundamental research to its applications in emerging fields such as nanotechnology and biotechnology, this description celebrates chlorotrimethylsilane's capacity to inspire curiosity, drive innovation, and unlock new possibilities in scientific inquiry.

    Items Specifications
    1. Chemical Structure Chlorotrimethylsilane consists of a silicon atom bonded to three methyl (CH3) groups and one chlorine (Cl) atom, represented by the chemical formula (CH3)3SiCl.
    2. Molecular Weight The molecular weight of chlorotrimethylsilane is approximately 108.62 grams per mole.
    3. Physical State It is a colorless liquid at room temperature with a pungent odor.
    4. Solubility Chlorotrimethylsilane is soluble in a variety of organic solvents such as benzene, ether, and dichloromethane, but it is immiscible with water.
    5. Reactivity It is highly reactive and can undergo various chemical reactions, including hydrolysis, chlorination, and reactions with nucleophiles and electrophiles.
    6. Synthesis Prepared industrially by the reaction of trimethylchlorosilane with hydrogen chloride or by the direct chlorination of trimethylsilane.
    7. Uses - Widely used as a reagent in organic synthesis for the introduction of trimethylsilyl groups (-Si(CH3)3) onto organic molecules.

    - Employed in the production of organosilicon compounds, silicone polymers, and as a protective agent for hydroxyl groups in chemical reactions.
    8. Protective Agent Chlorotrimethylsilane is commonly used as a protective agent for hydroxyl groups (–OH) in the synthesis of esters, ethers, and other organic compounds.
    9. Hydrophobicity Due to the presence of trimethylsilyl groups, it imparts hydrophobic properties to organic molecules, making it useful in surface modification and material science.
    10. Safety Precautions Handling of chlorotrimethylsilane requires proper safety precautions due to its reactivity and potential hazards. Protective equipment and adequate ventilation are necessary.
    11. Storage It should be stored in tightly sealed containers, away from heat, ignition sources, and incompatible materials to prevent accidents and deterioration.
    12. Environmental Impact Chlorotrimethylsilane may pose environmental risks if released into the environment. Proper disposal methods and containment measures should be implemented.
    13. Regulatory Status Regulated by government agencies due to its hazardous properties. Compliance with safety regulations and guidelines is essential for its production and use.
    14. Industrial Applications Used in various industries including pharmaceuticals, agrochemicals, plastics, and electronics for its versatile reactivity and ability to modify organic compounds.
    15. Research Ongoing research explores new synthetic methodologies and applications of chlorotrimethylsilane in organic synthesis, materials science, and surface modification.







      Product Detail  


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    Basic Info
    Product Name:

    Chlorotrimethylsilane

    Other Name:

    Silane,chlorotrimethyl-;Chlorotrimethylsilane;Trimethylchlorosilane;Trimethylsilyl chloride;Trimethylsilicon chloride;Monochlorotrimethylsilicon;Trimethylsilane chloride;TSL 8031;Monochlorotrimethylsilane;KA 31;KA 31 (silane);NSC 15750;TMCS;LS 260;TMSCl;127290-36-2;36642-33-8

    CAS No.:

    75-77-4

    Molecular Formula:

    C3H9ClSi

    InChIKeys:

    InChIKey=IJOOHPMOJXWVHK-UHFFFAOYSA-N

    Molecular Weight:

    108.64200

    Exact Mass:

    108.64

    EC Number:

    200-900-5

    UNII:

    62UO4690X6

    ICSC Number:

    0966

    NSC Number:

    15750

    UN Number:

    1298

    DSSTox ID:

    DTXSID2024822

    Color/Form:

    Colorless liquid

    HScode:

    29310095

    Categories:

    Analysis Reagents

    Characteristics
    PSA:

    0

    XLogP3:

    2.06010

    Appearance:

    Trimethylchlorosilane appears as a colorless fuming liquid with a pungent odor. Boiling point 135° F, Flash point -18°F. Density 0.854 g / cm3. The vapor and liquid may cause burns. Vapors are heavier than air.

    Density:

    0.854 g/cm3 @ Temp: 25 °C

    Melting Point:

    -57.7 °C

    Boiling Point:

    57 °C

    Flash Point:

    -18ºC

    Refractive Index:

    1.387-1.389

    Water Solubility:

    Solubility in water: reaction

    Storage Conditions:

    Store at RT.

    Vapor Pressure:

    100 mm Hg ( 25 °C)

    Vapor Density:

    3.7 (vs air)

    Toxicity:

    LD50 orally in Rabbit: 4868 mg/kg LD50 dermal Rabbit 1530 mg/kg

    Flammability characteristics:

    LOWER 1.8%

    Explosive limit:

    vol% in air: 1.8

    Odor:

    SHARP, HYDROCHLORIC ACID-LIKE ODOR; ACRID.

    Experimental Properties:

    Ratio of specific heats of vapor (gas): 1.0683. (est)|Readily hydrolyzed with liberation of hydrochloric acid|Organo-functional silanes are noted for their ability to bond organic polymer systems to inorganic substrates /Silane cmpd/|The reaction of organosilanes with halogens and halogen cmpd usually proceeds in good yield through cleavage of the Si--H bond and formation of the silicon-halogen bond. Reaction with fluorine, however, does not proceed satisfactorily because of cleavage of not only the Si--H but also C--Si and C--H bonds. Direct halogenation with chlorination, bromine, and iodine proceeds smoothly, however. /Organosilanes/|Hydroxyl radical reaction rate constant = 4.49X10-13 cu cm/molec sec at 25 °C (est)

    Air and Water Reactions:

    Highly flammable. Fumes in air. Reacts vigorously and exothermically with water. Products of the reaction include hydrogen chloride. The heat may be sufficient to ignite nearby combustible materials. Trimethylchlorosilane reacts vigorously with water to generate gaseous HCl. Based on a scenario where the chemical is spilled into an excess of water (at least 5 fold excess of water), half of the maximum theoretical yield of Hydrogen Chloride gas will be created in 1.3 minutes. Experimental details are in the following: "Development of the Table of Initial Isolation and Protective Distances for the 2008 Emergency Response Guidebook", ANL/DIS-09-2, D.F. Brown, H.M. Hartmann, W.A. Freeman, and W.D. Haney, Argonne National Laboratory, Argonne, Illinois, June 2009.

    Reactive Group:

    Chlorosilanes

    Reactivity Alerts:

    Highly Flammable

    Reactivity Profile:

    TRIMETHYLCHLOROSILANE reacts vigorously and exothermically with water to produce hydrogen chloride.

    Autoignition Temperature:

    743 °F (USCG, 1999)|743 °F (395 °C)|395 °C

    Heat of Combustion:

    -10,300 BTU/LB (EST)

    Flammable Limits:

    Lower flammable limit: 1.8% by volume; Upper flammable limit: 6.0% by volume|LOWER 1.8%

    Physical Dangers:

    The vapour is heavier than air and may travel along the ground; distant ignition possible.

    Heat of Vaporization:

    126 BTU/LB

    Hazard Identification

    Classification of the substance or mixture

    Flammable liquids, Category 2

    Acute toxicity - Category 3, Oral

    Acute toxicity - Category 4, Dermal

    Skin corrosion, Sub-category 1A

    Acute toxicity - Category 3, Inhalation

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H225 Highly flammable liquid and vapour

    H301 Toxic if swallowed

    H312 Harmful in contact with skin

    H314 Causes severe skin burns and eye damage

    H331 Toxic if inhaled

    Precautionary statement(s)
    Prevention

    P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.

    P233 Keep container tightly closed.

    P240 Ground and bond container and receiving equipment.

    P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.

    P242 Use non-sparking tools.

    P243 Take action to prevent static discharges.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower].

    P370+P378 In case of fire: Use ... to extinguish.

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P317 Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

    P363 Wash contaminated clothing before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P316 Get emergency medical help immediately.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    Storage

    P403+P235 Store in a well-ventilated place. Keep cool.

    P405 Store locked up.

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    NO open flames, NO sparks and NO smoking. NO contact with hot surfaces. Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Fireproof. Separated from food and feedstuffs and other compounds. Cool. Dry. Well closed.Storage temperature; ambient.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

    Location:

    13 PROTEA PARK MILKWOOD STREET RANGEVIEW GAUTENG 1739

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment

    Average lead Time:

    60

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2012

  • Inquiry History
    3 Inquiries
    Country Product Purchase Quantity Date Posted
    South Korea

    TMCS Trimethylchlorosilane

    1 MT Jan 14, 2026
    India

    Chlorotrimethylsilane 99% powder or vials/Liquid or oily/Crystal or Ointment Chlorotrimethylsilane

    1 MT Jun 30, 2023
    Romania

    Trimethylchlorosilane

    680 KG Sep 30, 2025
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