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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Tacrolimus for Sale > Best price FK-506 pure 99% Tacrolimus raw powder cas 104987-11-3
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Best price FK-506 pure 99% Tacrolimus raw powder cas 104987-11-3

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Unit Price: Get Latest Price
CAS No.:

104987-11-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenshen

Brand:

HORLDEN

Packaging:

1g/bottle

Price valid (until):

2026-02-26

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Shop Best price FK-506 pure 99% Tacrolimus raw powder cas 104987-11-3-Detailed Image 1

    Shop Best price FK-506 pure 99% Tacrolimus raw powder cas 104987-11-3-Detailed Image 2

    Product Name  Tacrolimus
    CAS NO. 104987-11-3
    Purity 99%
    Molecular Formula C44H69NO12
    MOQ  1 g

    Tacrolimus is a macrolide drug isolated from Streptomyces, which has a strong immunosuppressive effect. It can specifically bind and inhibit the activity of calcineurin phosphatase, inhibit IL-2 signal transcription, thereby inhibiting T cell activation, inhibiting the production of TNF-α, IL-1β and IL-6, and T cell-dependent B cell proliferation. Compared with cyclosporine, another calcineurin phosphatase inhibitor, tacrolimus has a stronger effect in inhibiting T cell activation and fewer adverse reactions.

    Shop Best price FK-506 pure 99% Tacrolimus raw powder cas 104987-11-3-Detailed Image 3

    You can ask us for quotation and product information via Email, Phone, WhatsApp and other channels.

    Email: rock@horlden.com
    WhatsApp/ wechat: +86 18829283179

    Shop Best price FK-506 pure 99% Tacrolimus raw powder cas 104987-11-3-Detailed Image 4

    1.What's your payment terms?

    Standard terms: T/T in advance. Also L/C at sight is acceptable for large amount.

    2.What's your shipping time?

    We have bulk in stock, which means we can ship it to you immediately.

    3.How do you ensure the quality of your products?

    Strict QC with 6 steps testing from raw material purchase to finished product.

    4.How do you ship the order normally?

    For large qty order,ship the goods by sea. For small qty order, by air or express. We supply optional express for you, including DHL, FEDEX,UPS,TXT,EMS,and so on.

    5.What's your loading port?

    Usually Beijing, Shanghai, Qingdao, Tianjin, Guangzhou

    Certificates

    Basic Info
    Product Name:

    Tacrolimus

    Other Name:

    15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-,(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-;15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,[3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-;15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-;(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone;FR 900506;FK 506;Tsukubaenolide;L 679934;Fujimycin;(-)-FK 506;Tacrolimus;Prograf;Protopic;Advagraf;TacroBell;FK506;Prograph;Envarsus XR;Astagraf XL;Hecoria;Tacropic;Protopy;Modigraf;Envarsus

    CAS No.:

    104987-11-3

    Molecular Formula:

    C44H69NO12

    InChIKeys:

    InChIKey=QJJXYPPXXYFBGM-LFZNUXCKSA-N

    Molecular Weight:

    804.02

    Exact Mass:

    804.02

    EC Number:

    1308068-626-2

    DSSTox ID:

    DTXSID5046354

    Characteristics
    PSA:

    178 Ų

    XLogP3:

    3.3

    Appearance:

    white solid

    Density:

    1.2±0.1 g/cm3

    Melting Point:

    113-115°C

    Flash Point:

    2℃

    Refractive Index:

    1.549

    Water Solubility:

    Freely soluble in DMSO or ethanol. Poorly soluble in water.soluble in dimethyl sulfoxide, ethanol, water, acetone, chloroform, ethyl acetate, ether, methanol and dimethyl formamide.DMSO: >3 mg/mL

    Storage Conditions:

    −20°C

    Vapor Pressure:

    8.37X10-32 mm Hg at 25 °C (est)

    Henrys Law Constant:

    Henry's Law constant = 4.74X10-24 atm-cum/mol at 25 °C (est)

    Dissociation Constants:

    pKa1 = 2.94; pKa2 = 9.95; pKa3 = 14.07 (est)

    Experimental Properties:

    Hydroxyl radical reaction rate constant = 3.81X10-10 cu cm/molec-sec at 25 °C (est)|Ozone radical reaction rate constant = 8.719X10-16 cu cm/molec-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 3, Oral

    Reproductive toxicity, Category 2

    Specific target organ toxicity – repeated exposure, Category 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H301 Toxic if swallowed

    H361 Suspected of damaging fertility or the unborn child

    H372 Causes damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide

    Location:

    10712,floor7,Unit 1,Buiding5,Silk Road International Creative Dreamwordks,No.3639,xi'an,shaanxi

    Payment Terms:

    100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    11-50

    Year of Establishment:

    2015

    Xi'an Horlden Bio Industries Ins is committed to promoting health application products such as chemical daily necessities, APIs, pharmaceutical intermediates and Cosmetic raw materials.

    We have established friendly business relationships with hundreds of customers from over 50 countries and regions. Our team is committed to providing customers with the highest quality products at reasonable prices and satisfactory service. For many years, our company has won the trust and favor of our customers with high-quality products, first-class services, and competitive prices.

    We will create the highest quality and most stable supply channel for customers, adhering to the spirit of serving customers, relying on strong funds and good cooperation reputation in the industry, to provide customers with higher quality products and services. At the same time, we are willing to strengthen exchanges and sincere cooperation with domestic and foreign merchants to create a better future together. It is your best supplier.

    Welcome to Xi'an Horlden Bio Industries Ins !

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    Uzbekistan

    China GMP Factory Direct Supply 99% Purity Tacrolimus FK-506 powder CAS 104987-11-3 Sinoway

    1 KG Oct 12, 2023
    Saudi Arabia

    Tacrolimus

    10 G Sep 14, 2024
    Post an enquiry for this product
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