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Hydroxypropyl methylcellulose ( HPMC)

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CAS No.:

9004-65-3

Port:

中国

Packaging:

25kg/drum

Price valid (until):

2025-03-03

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QINGDAO EAST CHEMSOURCES TRADE CO.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Food additives,Pharmaceutical raw materials,Chemicals,Comestic raw materials

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Basic chemical information

Hydroxy Propyl Methyl Cellulose (HPMC for short) is a non-ionic cellulose ether. It is obtained by chemically modifying natural cellulose (such as cotton linter or wood pulp). From a chemical structure perspective, it introduces hydroxypropyl (-CH₂CH(OH)CH₃) and methyl (-CH₃) ether bonds onto the cellulose molecular chain.
This chemical structure endows it with many unique properties. Its molecular formula can be roughly expressed as, where and represent the degree of substitution, and their values will vary according to the specific specifications of the product.

Physical properties

Appearance: Usually a white or off-white powder or granular substance. The uniformity of its appearance helps in uniform dispersion in various applications.
Solubility: It has good water solubility and can form a transparent viscous solution in water. This is because the polar groups such as hydroxyl groups in its molecular structure can form hydrogen bonds with water molecules. It can swell and dissolve in cold water, but the dissolution speed is relatively slow; in hot water, its dissolution process may be hindered by the formation of a gel layer, but proper stirring can promote dissolution.
Viscosity: The viscosity of HPMC varies depending on the product model and concentration. It can provide multiple choices from low viscosity to high viscosity to meet the needs of different application scenarios. For example, in the construction industry, higher viscosity HPMC can be used to increase the consistency of cement mortar; in some coating applications, lower viscosity products may be used to adjust the rheological properties of coatings.

Chemical properties

Stability: It has good chemical stability and is relatively stable under general acidic and alkaline environments. However, under strong acidic or alkaline conditions, its molecular chain may undergo hydrolysis reactions, resulting in a decrease in its performance. It also has a certain degree of thermal stability, but at high temperatures, degradation may occur over time.
Reactivity: Due to the functional groups such as hydroxyl and ether bonds in its molecular structure, it can react with some chemical reagents. For example, it can undergo condensation reactions with aldehyde substances to prepare materials with special properties.

Uses

Construction industry: It is an important additive for construction materials. In cement mortar, it can play roles such as water retention, thickening, and retardation. The water retention function can prevent cement mortar from losing water too quickly during construction, thereby improving its bonding strength and construction performance; the thickening function can make the mortar have good plasticity and sag resistance, facilitating construction operations. In gypsum products, it can also improve the setting time and strength of gypsum and other properties.
Paint industry: Used as a thickener, rheology modifier, and stabilizer for coatings. It can adjust the viscosity and rheological properties of coatings, making coatings have good stability during storage and construction. For example, it can prevent precipitation and stratification of coatings during storage, and at the same time, it can make coatings evenly coated on the surface of objects during construction.
Pharmaceutical industry: In pharmaceutical preparations, it can be used as a binder and coating material for tablets. As a binder, it can bind drug powders into solid tablets; as a coating material, it can control the release rate of drugs, play a sustained-release role, and also protect drugs from the influence of the external environment, such as preventing drugs from being oxidized or dampened.
Food industry: It is an allowed food additive, mainly used as a thickener, emulsifier, and stabilizer. For example, in some sauces, jellies and other foods, it can increase the viscosity of products and improve the taste; in ice cream and other products, it can prevent the formation of ice crystals and improve the stability and taste of products.

Production method

It is mainly produced through alkalization-etherification reaction. First, natural cellulose raw materials are alkalized with alkali solution (such as sodium hydroxide) to activate the hydroxyl groups on the cellulose molecules. Then, methylation reagents (such as chloromethane) and hydroxypropylation reagents (such as propylene oxide) are added, and etherification reaction is carried out under certain temperature, pressure and reaction time conditions to introduce methyl and hydroxypropyl groups into the cellulose molecular chain. Finally, HPMC products are obtained through post-treatment (such as neutralization, washing, drying, etc.).

Items	Specifications

Basic Info

Product Name:

Hydroxypropyl methyl cellulose

Other Name:

Cellulose,2-hydroxypropyl methyl ether;Hydroxypropyl methyl cellulose ether;Methocel X 2602;Methyl hydroxypropyl cellulose;Cellulose hydroxypropyl methyl ether;Methocel HG 65;Methocel HG 60;Methofas PM;Methocel HG;Courlose HPM;Methocel J 12HS;Methocel HG 90;2-Hydroxypropyl methyl cellulose;Methofas PM 4500;Celacol HPM 450;Methocel E;Methocel F;Methocel K;Pharmacoat 603;Methocel 60HG4000;Celacol HPM 5000;HPMC 20000PV;Pharmacoat 606;TC 5R;Methocel XD 1214;Methocel XD 1214.44;Methocel HG 228;Methocel K 4M Premium;Methocel K 4M;Metolose 90SH4000;Methocel 50;MOPTs;Metolose 60SH50;Methocel 228;Synchron-Oral;Methocel F 4M;Methocel K 15M-DGS;MC 400;Metolose 90SH15000;Methocel E 15;Culminal MHPC;Methocel F 7M;Culminal MHPC 6000;TC 5;Metolose 90SH100;Synchron;Methocel K 100M;Methocel E 5;Methocel J;Methocel E 15LV;Methocel E 50;Methocel K 100;Methocel E 4M;Methocel MK 4;Metolose 90SH30000;Celacol HPM 15000DS;Metolose 65SH50;Methocel J 75MS;Metolose 65SH400;Methocel J 75;Methocel K 15MS;Metolose SH 4000;Hypromellose;Viscontran MHPC 50;Marpolose MP 4000;Metolose 60SH4000;Methocel J 5MS;Methocel F 50;2-Hydroxypropyl methyl cellulose ether;Methocel 90HG40;Walocel MW 60GA;Walocel MK 3.000PF;Culminal MHPC 20000PR;Methocel K 4MS;Metolose 90SH3000;Metolose 65SH4000;Hydroxypropyl methyl cellulose;Marpolose 60MP5;Celacol 15000DS;Methocel K 15M;Metolose 65SH1500;TC 5E;Methofas PM 450;8063-82-9;11106-33-5;12673-53-9;37341-76-7;39363-71-8;59029-31-1;62683-26-5;65607-39-8;68073-10-9;71373-07-4;98112-80-2;125053-98-7;125857-43-4;137397-89-8;137397-90-1;137397-91-2;171544-38-0;173080-61-0;194615-25-3;876407-53-3;1262284-64-9;2227180-04-1;2258661-54-8;2376293-65-9

CAS No.:

9004-65-3

Molecular Formula:

C3H8O2.xCH4O.xUnspecified

Molecular Weight:

59.08708

EC Number:

220-971-6

HScode:

39129000

Categories:

Coating Additive

Characteristics

XLogP3:

0.00000

Appearance:

White to cream powder

Density:

1.326 g/cm³

Melting Point:

225-230 °C

Water Solubility:

H2O: 50 mg/mL, clear to very faintly turbid, faintly yellow

Storage Conditions:

Hypromellose powder is a stable material, although it is hygroscopic after drying.
Solutions are stable at pH 3–11. Hypromellose undergoes a reversible sol–gel transformation upon heating and cooling, respectively. The gelation temperature is 50–90°C, depending upon the grade and concentration of material. For temperatures below the gelation temperature, viscosity of the solution decreases as temperature is increased. Beyond the gelation temperature, viscosity increases as temperature is i

See More Hydroxypropyl methyl cellulose Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Hydroxypropyl methyl cellulose Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Food additives,Pharmaceutical raw materials,Chemicals,Comestic raw materials

Location:
Room 501, Unit 6, No. 40, hushan road,Licang,Qingdao

Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2017

QINGDAO EASTCHEMSORCES TRADE LIMITED is a leading Manufactory supplier of Sorbitol, Citric acid, Sodium hypochlorite based in Qingdao, Shandong, China. With a commitment to quality and customer satisfaction, QINGDAO EASTCHEMSORCES TRADE LIMITED has become a trusted name in the industry. Our product line includes a range of high-quality Sorbitol, Citric acid, Sodium hypochlorite, which are available at competitive prices. QINGDAO EASTCHEMSORCES TRADE LIMITED has established itself as a reliable supplier of chemical products on the echemi.com.

Inquiry History

218 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	HPMC	1 KG	Dec 24, 2025
Germany	Hydroxypropyl Methylcellulose	500 TON	Jun 15, 2024
India	HPMC	100.00 KG	Jun 6, 2025
India	HPMC	400.00 KG	May 30, 2025
India	HPMC	50.00 KG	Jun 7, 2025
India	HPMC	400.00 KG	May 29, 2025
India	HPMC	30.00 KG	May 21, 2025
India	HPMC	50.00 KG	May 14, 2025
India	HPMC	100.00 KG	Jun 7, 2025
India	HPMC	50.00 KG	May 14, 2025
India	Hydroxypropyl Methyl Cellulose (HPMC)	1.00 MT	Dec 7, 2023
India	HPMC	100.00 KG	Jun 7, 2025
India	HPMC	30.00 KG	May 27, 2025
India	HPMC	50.00 KG	Jun 6, 2025
India	Hydroxypropyl Methyl Cellulose (HPMC)	1.00 MT	Nov 20, 2023
Bahrain	HPMC	1.00 20' Fcl	May 10, 2024
Bangladesh	HPMC	1.00 20' Fcl	Oct 11, 2024
India	Hydroxypropyl Methyl Cellulose (HPMC)	10.00 MT	Jul 13, 2023
India	HPMC	25.00 KG	Jun 11, 2025
Philippines	HPMC	1 MT	May 4, 2026

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