Product
Supplier
Encyclopedia
Inquiry
Pemetrexed Disodium buy - large image1
Pemetrexed Disodium buy - image1
Pemetrexed Disodium buy - image2
Pemetrexed Disodium buy - image3

Pemetrexed Disodium

GMP COA

Unit Price: Get Latest Price
CAS No.:

150399-23-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

Simcere

Packaging:

5kg/Cardboard Drum

Price valid (until):

2025-01-31

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Diosmectite,Bedaquiline FuMarate,Iguratimod,Edoxaban Tosylate,Edaravone,Borneol

  • Product Description

  • Seller Information

  • Description


      Product Detail  


    Description

    Pemetrexed disodium (marketed as ALIMTA®, “pemetrexed”) is a novel, multi-targeted antifolate. It suppresses tumor growth by impeding both DNA synthesis and folate metabolism. Pemetrexed disodium has demonstrated promising clinical activity in a wide variety of solid tumors, including non-small cell lung, breast, mesothelioma, colorectal, pancreatic, gastric, bladder, cervix, and head and neck.
    Pemetrexed disodium is approved to be used alone or with other drugs to treat malignant pleural mesothelioma in patients who cannot be treated with surgery and non-small cell lung cancer (certain types) in patients whose disease is locally advanced or has metastasized (spread to other parts of the body). Pemetrexed disodium is also being studied in the treatment of other types of cancer.

    Items Specifications
    Melting point  254-258°C (dec.)
    form  Solid
    color  Off-White
    solubility  Methanol, Water

    Certificates

    Basic Info
    Product Name:

    L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, sodium salt (1:2)

    Other Name:

    L-Glutamic acid,N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-,sodium salt (1:2);L-Glutamic acid,N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-,disodium salt;1H-Pyrrolo[2,3-d]pyrimidine,L-glutamic acid deriv.;Tifolar;Pemetrexed disodium;Rolazar;LY 231514;Alimta;LY 231514 disodium;Pemetrexed sodium

    CAS No.:

    150399-23-8

    Molecular Formula:

    C20H21N5O6.2Na

    InChIKeys:

    InChIKey=PSXPIRGEVYHPKP-GXKRWWSZSA-N

    Molecular Weight:

    471.37

    Exact Mass:

    471.113068

    EC Number:

    1312995-182-4

    UNII:

    2PKU919BA9

    DSSTox ID:

    DTXSID8046660|DTXSID50189238|DTXSID10189239

    NCI Thesaurus Code:

    C1533

    ATC Code:

    L01BA04

    HScode:

    2933990090

    Categories:

    Antineoplastic Agents

    Characteristics
    PSA:

    196.92000

    XLogP3:

    -1.03090

    Appearance:

    Crystalline Solid

    Melting Point:

    36-38°C

    Boiling Point:

    160°C 20mm

    Flash Point:

    160°C/20mm

    Storage Conditions:

    -20°C Freezer

    Hazard Identification

    Classification of the substance or mixture

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    Germ cell mutagenicity, Category 2

    Reproductive toxicity, Category 1B

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    H341 Suspected of causing genetic defects

    H360 May damage fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    P203 Obtain, read and follow all safety instructions before use.

    Response

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    P318 IF exposed or concerned, get medical advice.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Diosmectite,Bedaquiline FuMarate,Iguratimod,Edoxaban Tosylate,Edaravone,Borneol

    Location:

    No. 109, Changfenghe Road, Jiangbei New District, Nanjing

    Payment Terms:

    100% TT in advance

    Average lead Time:

    30

    Total Annual Revenue:

    Above $100 million

    Total Employees:

    Above 1000

    Year of Establishment:

    2022

    Simcere Pharmaceutical Group Limited (2096.HK) is a pharmaceutical company driven by innovative R&D. We are committed to "providing today's patients with medicines of the future" across the following core therapeutic areas: oncology, central nervous system, autoimmunity and anti-infection. Furthermore, we are also actively expanding our presence in disease areas with significant clinical needs in the future.

    Our industry-leading capabilities and commitment to synergistic innovation have also enabled various strategic collaborations and we are seen as the partner of choice by innovative biopharmaceutical companies, medical institutes, and research teams in China and globally.
  • Country Product Purchase Quantity Date Posted
    Post an enquiry for this product
pic ×

Scan the QR Code to Share

All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.

According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

The information shown above is provided by the enterprise itself, and the authenticity, accuracy and legitimacy of the content are the responsibility of the publishing company. ECHEMI does not bear any guarantee responsibility for this. Please be aware that risks in internet transactions objectively exist.

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.