Best quality Fast delivery lcatibant CAS 138614-30-9
GMP FDA
138614-30-9
Pharmaceutical Grade
99%
Shang Hai
KDG
1g/bottle
Yes
2025-04-07
Peptide,API,HCG,Amino Acids,Plant Extract,Vitamin
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceAlthough it is a rare disease, HAE is an autosomal dominant disorder that can be potentially life-threatening when swelling manifests itself within the upper airways. Antagonism of the constitutively expressed B2 receptor, therefore, would not only be beneficial in the treatment of HAE but also find application in inflammatory, allergic, and hyperalgesic disorders.Designed to possess enhanced metabolic stability with the inclusion of five non-proteinogenic amino acids, icatibant is a competitive and selective B2 receptor antagonist (devoid of activity against the inducible B1 receptor) with a Kiof 2.2±0.7 nM, and it is the first downstream targeting agent to receive regulatory approval. It joins purified C1 esterase inhibitor, danazol (an attenuated androgen), and tranexamic acid (an antifibrinolytic agent) as acute and prophylactic treatments for HAE.
ChEBI: An acetate salt obtained by combining icatibant with acetic acid. Used for the treatment of acute attacks of hereditary angioedema in adult patients.CertificatesBasic Info-
Product Name:
Icatibant Acetate
Other Name:HOE-140 (Icatibant);HOE140; ICATIBANT;HOE 140;CS-1399;Firazyr;HOE 140 SYNTHETIC >99% SELECTIVE B2 BRAD YKIN;d-arg-l-arg-l-pro-l-hyp-gly-l-(2-thienyl)ala-l-ser-d-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-l-(2α,3β,7aβ)-octahydro-1h-indole-2-carbonyl-l-arg;Icatibant acetate, D-Arg-L-Arg-L-Pro-L-Hyp-Gly-L-(2-thienyl)Ala-L-Ser-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3β,7aβ)-octahydro-1H-indole-2-carbonyl-L-Arg;HOE 140 Acetate
CAS No.:138614-30-9
Molecular Formula:C59H89N19O13S.C2H4O2
InChIKeys:HKMZRZUEADSZDQ-SUJPMXFINA-N
Molecular Weight:1364.59
EC Number:206-141-6
Color/Form:White to off-white
Categories:
Characteristics-
Critical Temperature & Pressure:
-20°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Peptide,API,HCG,Amino Acids,Plant Extract,Vitamin
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Location:
Room H0413, Building 1, No. 58, Guanggu Avenue, East Lake New Technology Development,Wuhan
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Year of Establishment:
2020
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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