High Quality Pharmacy Grade 99% Citiolone 987-78-0 With Fast Delivery Best Price

Citiolone More Info

Citiolone is a synthetic compound developed as a hepatoprotective agent and mucolytic drug. Chemically identified as N-acetyl-L-cysteine ethyl ester, it functions as a precursor to glutathione, playing a crucial role in hepatic detoxification processes. The molecular structure combines characteristics of amino acid derivatives with ester functionality, enhancing its bioavailability compared to earlier hepatoprotective agents. Developed during mid-20th century pharmaceutical research, citiolone was designed to support liver function through multiple mechanisms including glutathione synthesis enhancement and free radical scavenging. The compound's metabolic pathway involves conversion to active metabolites that participate in crucial biochemical processes within hepatocytes, particularly in Phase II detoxification reactions.

Uses and Applications

The primary therapeutic applications of citiolone focus on hepatic disorders and respiratory conditions. It is clinically used as a hepatoprotective agent in various liver diseases including toxic hepatitis, drug-induced liver injury, and alcoholic liver disease. The compound demonstrates dual functionality by also serving as a mucolytic agent in respiratory disorders such as chronic bronchitis and bronchiectasis, where it helps reduce mucus viscosity. Additional applications include adjunctive therapy in certain metabolic disorders and as a protective agent against hepatotoxic substances. The medication is typically administered in oral dosage forms including tablets and sachets, with some regions also providing injectable formulations for hospital use. Treatment protocols generally involve courses of several weeks with dosage adjustments based on clinical indication and patient response.

Application Market

The market for citiolone demonstrates significant regional variation, with established presence in European, Asian, and Latin American pharmaceutical markets while maintaining limited availability in North America. As a generic medication, it is manufactured by multiple pharmaceutical companies under various brand names and is included in several national formularies for hepatology and gastroenterology. Market distribution occurs primarily through retail pharmacies with hospital utilization for specific inpatient indications. The market is characterized by stable but regionally concentrated demand patterns, influenced by local treatment traditions and healthcare system structures. Competition exists from other hepatoprotective agents and mucolytic drugs, though citiolone maintains its market position through established efficacy data and physician familiarity in regions where it has been historically prescribed.

Important Considerations

Clinical use of citiolone requires appropriate patient selection and adherence to recommended dosage guidelines. Important precautions include monitoring for potential gastrointestinal side effects such as nausea and epigastric discomfort, particularly during initial treatment phases. The medication should be used with caution in patients with severe renal impairment or active peptic ulcer disease. Concomitant use with certain antibiotics, particularly aminoglycosides, may require dosage interval adjustment. Patients should be advised regarding proper administration timing, typically between meals for optimal absorption unless gastrointestinal intolerance occurs. Storage conditions should maintain product stability within manufacturer specifications, with particular attention to moisture protection for hygroscopic formulations. Healthcare providers should consider regional availability and regulatory status when prescribing, as approval status and indicated uses vary significantly between different national drug regulatory agencies.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
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Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.