4-Aminosalicylic acid RC02571
65-49-6
99%
Royalchem
25kg/drum
2029-12-31
Pharmaceutical intermediates
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Product Description
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Seller Information
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DescriptionECHEMI Editorial Reference4-Aminosalicylic acid (ASA) is an orally active antibiotic and has the potential to treat tuberculosis[1].
Solid
4-aminosalicylic acid is an aminobenzoic acid that is salicylic acid substituted by an amino group at position 4. It has a role as an antitubercular agent. It is an aminobenzoic acid and a member of phenols. It derives from a salicylic acid. It is a conjugate acid of a 4-aminosalicylate(1-).|An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.|Aminosalicylic Acid is an analog of para-aminobenzoic acid (PABA) with antitubercular activity. Aminosalicylic acid exerts its bacteriostatic activity against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis, thereby suppressing growth and reproduction of M. tuberculosis, eventually leading to cell death.|An antitubercular agent often administered in association with ISONIAZID. The sodium salt of the drug is better tolerated than the free acid.Basic Info-
Product Name:
4-Aminosalicylic acid
Other Name:Benzoic acid,4-amino-2-hydroxy-;Salicylic acid,4-amino-;4-Amino-2-hydroxybenzoic acid;Apacil;Apas;Deapasil;Pamacyl;Para-Pas;Parasal;Parasalicil;Parasalindon;PAS (acid);Pasara;Pasem;Pasmed;Pasnodia;Propasa;Rezipas;PASK;2-Hydroxy-4-aminobenzoic acid;Para-aminosalicylic acid;Pasolac;Sanipirol-4;3-Hydroxy-4-carboxyaniline;Paramycin;Gabbropas;Amino-PAS;Osacyl;Pasalon;Entepas;Pasa;PAS;p-Aminosalicylic acid;4-Aminosalicylic acid;4-ASA;4-Carboxy-3-hydroxyaniline;Pamisyl;NSC 2083;NSC 211698;Monopass;Paser;Euteropas;Granupas;2220148-96-7
CAS No.:65-49-6
Molecular Formula:C7H7NO3
InChIKeys:InChIKey=WUBBRNOQWQTFEX-UHFFFAOYSA-N
Molecular Weight:153.14
Exact Mass:153.14
BRN:473071
EC Number:200-613-5
UNII:5B2658E0N2
NSC Number:2083
DSSTox ID:DTXSID2022591
NCI Thesaurus Code:C47394
Color/Form:MINUTE CRYSTALS FROM ALC|WHITE, OR NEARLY WHITE, BULKY POWDER|NEEDLES, PLATES FROM ALC-ETHER|A reddish-brown crystalline powder is obtained on recrystallization from ethanol-ether.
ATC Code:J04AA01|J - Antiinfectives for systemic use
HScode:29225000
Categories:
Characteristics-
PSA:
83.6
XLogP3:1.3
Appearance:Colorless Powder
Density:1.5±0.1 g/cm3
Melting Point:150.5 °C (decomp)
Boiling Point:347ºC
Flash Point:184.1±25.1 °C
Refractive Index:1.691
Water Solubility:H2O: 2 g/L (20 ºC)
Storage Conditions:Store at 0-5°C
Toxicity:Peritoneal-mouse LD50: 4250 mg/kg; oral-mouse LD50: 4000 mg/kg
Flammability characteristics:Flammable; burning produces toxic nitrogen oxide fumes
Odor:ODORLESS, OR HAS SLIGHT ACETOUS ODOR
PH:PH (SATURATED AQ SOLN): BETWEEN 3 & 3.7
PKA:2.05(at 25 °C)
Dissociation Constants:2.05 (at 25 °C)|PKA: 3.25
Experimental Properties:PH OF 0.1% AQ SOLN: 3.5|CRYSTALS; DECOMP @ 224 °C /HYDROCHLORIDE/|WHITE TO CREAM-COLORED CRYSTALS OR POWDER; ODORLESS, & HAS ALKALINE, SLIGHTLY BITTER TASTE /CALCIUM SALT/|WHITE TO CREAM-COLORED, CRYSTALLINE POWDER; PRACTICALLY ODORLESS & HAS SALINE TASTE /POTASSIUM SALT/|For more Other Experimental Properties (Complete) data for P-AMINOSALICYLIC ACID (7 total), please visit the HSDB record page.
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store below 90 deg C (104 deg F), unless otherwise specified by manufacturer. Store in tight, light resistant containers.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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