Oxytetracycline hydrochloride Pharmacy Grade BP/USP Yellow Raw Power With Best Price

(+)-Camphor Bromide More Info

Chemical Profile and Structural Characteristics

Oxytetracycline hydrochloride (CAS 2058-46-0) is the hydrochloride salt form of oxytetracycline, a broad-spectrum tetracycline antibiotic produced by Streptomyces rimosus. This compound features a hydronaphthacene core structure with multiple functional groups including phenolic diketone systems and dimethylamine substituents. The hydrochloride salt formation significantly enhances the compound's water solubility and oral bioavailability compared to the base form, while maintaining the characteristic broad-spectrum antimicrobial activity of the tetracycline class.

Mechanism of Action and Antimicrobial Activity

The compound exerts its bacteriostatic effect through reversible binding to the 30S ribosomal subunit, inhibiting protein synthesis by blocking the attachment of aminoacyl-tRNA to the acceptor site on the mRNA-ribosome complex. This mechanism provides broad-spectrum activity against Gram-positive and Gram-negative bacteria, including Rickettsia, Mycoplasma, and certain protozoa. The hydrochloride salt form demonstrates improved tissue penetration and maintains effective concentrations at infection sites, contributing to its clinical efficacy across various infectious diseases.

Therapeutic Applications and Clinical Uses

Oxytetracycline hydrochloride is extensively used in human and veterinary medicine for treating respiratory infections, urinary tract infections, and sexually transmitted diseases. Specific applications include management of brucellosis, cholera, and psittacosis in human medicine, while veterinary applications encompass treatment of respiratory diseases in livestock and infectious keratoconjunctivitis in cattle. The compound is also employed in aquaculture for controlling bacterial infections in fish and shellfish, demonstrating versatility across multiple therapeutic domains.

Formulation Versatility and Pharmaceutical Applications

We supply Oxytetracycline hydrochloride suitable for various pharmaceutical formulations including oral capsules, tablets, topical ointments, and ophthalmic solutions. The compound demonstrates excellent compatibility with common pharmaceutical excipients and maintains stability in both solid and liquid dosage forms. Our technical data supports development of immediate-release formulations as well as specialized delivery systems for veterinary applications, with comprehensive guidance on optimal formulation strategies for different administration routes.

Quality Specifications and Analytical Standards

Our Oxytetracycline hydrochloride complies with USP, EP, and BP pharmacopeial standards, with rigorous quality controls including assay (95.0-102.0%), related substance profiling, and crystallinity characterization. Critical quality attributes encompass specific rotation, pH value of aqueous solutions, and limits for heavy metals and residual solvents. We employ validated HPLC methods with UV detection for precise quantification and impurity profiling, ensuring batch-to-batch consistency and regulatory compliance.

Safety Profile and Adverse Effect Management

The compound is generally well-tolerated, though common adverse effects include gastrointestinal disturbances such as nausea, vomiting, and diarrhea. More serious concerns include phototoxic reactions, tooth discoloration in children, and potential hepatotoxicity at high doses. Appropriate precautions include avoidance in pregnancy and childhood, monitoring of renal and hepatic function during prolonged therapy, and adherence to recommended dosage regimens to minimize adverse effects while maintaining therapeutic efficacy.

Stability Profile and Storage Requirements

Oxytetracycline hydrochloride requires protection from light and moisture, with recommended storage in tight, light-resistant containers at controlled room temperature. The compound demonstrates optimal stability in pH ranges of 2-5, while degradation accelerates under alkaline conditions. Our stability studies confirm 36-month shelf life when proper storage conditions are maintained, with comprehensive data available to support product development and regulatory submissions.

Regulatory Status and Global Approvals

Our Oxytetracycline hydrochloride API is supported by comprehensive regulatory documentation including DMFs in major markets and Certificates of Suitability. The compound is approved by numerous regulatory authorities worldwide and is listed in the WHO Essential Medicines List for specific therapeutic applications. Our manufacturing facilities maintain current Good Manufacturing Practice compliance and undergo regular inspections by international regulatory agencies.

Market Position and Competitive Landscape

As a well-established broad-spectrum antibiotic, Oxytetracycline hydrochloride maintains significant market share in both human and veterinary antimicrobial sectors. The expiration of patent protection has enabled robust generic competition while expanding access across global healthcare systems. Market growth continues to be driven by the compound's cost-effectiveness, proven efficacy, and versatility in treating various infectious diseases across different patient populations.

Manufacturing Capabilities and Supply Chain Assurance

We employ fermentation-based production using high-yield Streptomyces strains followed by purification and salt formation processes to ensure consistent quality and potency. Our manufacturing processes incorporate advanced purification technologies and rigorous in-process controls to minimize impurities and ensure batch-to-batch consistency. We maintain multiple production sites with flexible capacity to ensure reliable supply, supported by comprehensive quality agreements and robust logistics networks for global distribution.

Package Image

FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.