99% high quality SLUP-PP-322 CAS:303760-60-3 provide free sample at competitive price

Description

Sales manager : Jasmine

WeChat/WhatsApp: +852 6105 6303

Email: jasmine@jnsilkroad.com

Products Description

• 
  

  • • SLU-PP-332 is a pan-agonist of the estrogen receptor-related receptors (EC50’s cell-based cotransfection/reporter assay: ERRα = 98 nM, ERRß = 230 nM, ERRγ = 430 nM) with highest potency for ERRα. Developed to mimic the physiological benefits of exercise, it has shown promise in alleviating conditions such as obesity and metabolic syndrome in preclinical studies. This compound activates all three ERR isoforms, with a slightly higher potency towards ERRα, making it a significant candidate for therapeutic applications in metabolic diseases.
      

      Mechanism of Action

      SLU-PP-332 functions by activating ERRs, which are nuclear receptors involved in regulating energy metabolism. Upon administration, it induces a metabolic shift towards increased fatty acid oxidation and energy expenditure, similar to the physiological adaptations observed during exercise. Specifically, studies have shown that SLU-PP-332 leads to:
      1. Increased Fatty Acid Oxidation: A 25% increase compared to control groups.
      2. Decreased Carbohydrate Utilization: Indicating a preference for lipid metabolism.
      3. Enhanced Glucose Uptake: Notably in muscle tissues after prolonged treatment

      Applications

      SLU-PP-332 has potential applications in:
      1. Metabolic Syndrome Treatment: By reducing fat mass and improving insulin sensitivity.
      2. Obesity Management: Demonstrating efficacy in mouse models for weight loss and metabolic health improvement.
      3. Exercise Mimetic Research: Offering an alternative to physical exercise for those unable to engage in regular activity due to health constraints

      Safety and Side Effects

      While specific human clinical data on the safety profile of SLU-PP-332 are limited, preclinical studies indicate that it effectively reduces hepatic triglycerides without significant adverse effects noted in animal models. Further research is necessary to fully understand its safety profile and potential side effects in humans.

    
    

Jinan Silk Road Trading Co., Ltd is a high-tech company specializing in the research and development and production of polypeptide drugs. The company has an advanced industrial chain, covering the research and development, approval and industrialization of peptide raw materials and preparations. Its products include innovative drugs, raw materials, enzymes used in medicine and green synthesis industry, functional peptides and protein products.

Our core strengths are advanced polypeptide technology, strict quality control (conforming to cGMP standards), professional R&D team, and end-to-end solutions from raw materials to finished products.

We are committed to providing customers with high-quality and high-value products and services and have established a good reputation in the global market. With excellent product quality, logistics service and customer-centered business philosophy, our products have been exported to more than 100 countries.

Jinan Silk Road is willing to maintain cooperative relations with old and new friends and create a better future together!

1. Product Quality Assurance: We maintain stringent quality standards. Contact us for quality-related issues.

2. Returns and Refunds: Notify us of damaged or incorrect products. Refer to our Returns and Refunds Policy.

3. Technical Support: Reach our technical support team for assistance.

4. Order Tracking: Receive tracking information for your order.

5. Customer Feedback: Share your feedback with us.

6. Updates and Notifications: Subscribe to our newsletter for updates.