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Sucralose CAS:56038-13-2

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CAS No.:

56038-13-2

Grade:

Industrial Grade

Content:

98%

Port:

SHANGHAI

Brand:

Orient

Packaging:

1KG, 25KG, 200KG, 1000KG, customized

Price valid (until):

2026-01-09

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Focusing on innovative research, development, and production in the field of fine chemicals, we prioritize technology, quality, and market orientation. We collaborate with global partners to build a high-tech chemical industry chain and promote sustainable development in the industry.

The company's main products include pharmaceutical intermediates, food additives, essence, spices and plant extracts. The products have passed international certification and are exported to Europe, America, Japan, South Korea and Southeast Asia.

Sucralose Basic information

Product Name:	Sucralose
Synonyms:	1,6-dichloro-1,6-dideoxy-beta-d-fructofuranosyl4-chloro-4-deoxy-alpha-d-gala;4,1’,6’-trichloro-4,1’,6’-trideoxy-galacto-sucrose;alpha-d-galactopyranoside,1,6-dichloro-1,6-dideoxy-beta-d-fructofuranosyl4-ch;ctopyranoside;Sucralose in stock GMP Factory;1,6-dichloro-1;4,1',6'-trichlorogalactosucrose;loro-4-deoxy-
CAS:	56038-13-2
MF:	C12H19Cl3O8
MW:	397.63
EINECS:	259-952-2
Product Categories:	Food & Flavor Additives;Ring Systems;Food Ingredients;HISTOSTAT;Food addive,sweeteners;Food additives;Miscellaneous Biochemicals;pharmacetical;Oligosaccharide Compounds;Nutritional Supplements;Sweeteners;Oligosaccharides;56038-13-2
Mol File:	56038-13-2.mol

Sucralose Chemical Properties

Melting point	115-1018°C
alpha	D +68.2° (c = 1.1 in ethanol)
Boiling point	104-107 C
density	1.375 g/cm
vapor pressure	0Pa at 25℃
refractive index	1.604
storage temp.	2-8°C
solubility	DMF: 30 mg/ml DMSO: 30 mg/mlPBS (pH 7.2): 1 mg/ml
form	Powder
pka	12.52±0.70(Predicted)
color	White
PH	6-8 (100g/l, H2O, 20°C)
Odor	wh. cryst. powd., odorless, sweet taste
Optical Rotation	[α]/D 86.0±2.0°, c = 1 in H2O
Water Solubility	Soluble in Water.
Merck	14,8880
BRN	3654410
Stability:	Hygroscopic
LogP	-0.51 at 20℃
CAS DataBase Reference	56038-13-2(CAS DataBase Reference)
EPA Substance Registry System	.alpha.-D-Galactopyranoside, 1,6-dichloro-1,6-dideoxy-.beta.-D-fructofuranosyl 4-chloro-4-deoxy- (56038-13-2)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-37/39-24/25
WGK Germany	3
RTECS	LW5440140
HS Code	2932 14 00
Hazardous Substances Data	56038-13-2(Hazardous Substances Data)
Toxicity	LD50 orally in Rabbit: > 10000 mg/kg

MSDS Information

Sucralose Usage And Synthesis

Description	Sucralose is the only non-caloric sweetener made from sugar. It is in fact the latest non nutritive sweetener to have been approved by US FDA and other regulatory bodies and have hit the markets . Sucralose is derived from sugar through a multi-step patented manufacturing process that selectively substitutes three atoms of chlorine for three hydroxyl groups on the sugar molecule. This change produces a sweetener that has no calories, yet is 600 times sweeter than sucrose, making it roughly twice as sweet as saccharin and four times as sweet as aspartame.
Chemical Properties	Sucralose is a white to off-white colored, free-flowing, crystalline powder.
History	In 1975, sucralose was discovered by scientists from Tate & Lyle, working with researchers Leslie Hough and Shashikant Phadnis at Queen Elizabeth College (now part of King's College London). While looking for ways to use sucrose as a chemical intermediate, mixing sulfuryl chloride with sugar, Phadnis was told to "test" a chlorinated sugar compound. According to an anecdotal account, Phadnis thought Hough asked him to "taste" it, so he did and found the compound to be exceptionally sweet. Sucralose was first approved for use in Canada in 1991. Subsequent approvals came in Australia in 1993, in New Zealand in 1996, in the United States in 1998, and in the European Union in 2004. By 2008, it had been approved in over 80 countries, including Mexico, Brazil, China, India, and Japan. In 2006, the FDA amended the regulations for foods to include sucralose as a "non-nutritive sweetener" in food.
Uses	A low-calorie artificial sweetener
Uses	antiprotozoal
Uses	High intensity sweetener manufactured by replacing three hydroxyl groups on the sucrose molecule with three chlorine atoms. The results are a sweetener of 0 cal that is not digested. It is 600 times as sweet as sugar with a similar flavor profile. It is heat stable, readily soluble, and maintains its stability at elevated temperatures. It has been approved for use in specific categories that include baked products, beverages, confectioneries, and certain desserts and toppings.
Uses	Sucralose (1,6-dichloro-1,6-dideoxy-p-fructofuranosyl-4-chloro-oc- D-galactopyra- noside) is a nonnutritive sweetener based on sucrose. It is selectively chlorinated and the glycoside link between the two rings is resistant to hydrolysis by acid or enzymes, so it is not metabolized. It has 400 to 800 times the sweetness of sucrose, is very soluble in water, and is stable in heat. It can be used in food products that are baked or fried. Sucralose is produced by the selective chlorination of the sucrose molecule using a patented process by Tate and LyIe that replaces the three hydroxyl groups (OH) with three chlorine (Cl) atoms. This modified sugar is minimally absorbed by the body and passes out unchanged. It was approved for use in foods and beverages in 1999 in the United States.
Production Methods	Sucralose may be prepared by a variety of methods that involve the selective substitution of three sucrose hydroxyl groups by chlorine. Sucralose can also be synthesized by the reaction of sucrose (or an acetate) with thionyl chloride.
Definition	ChEBI: A disaccharide derivative consisting of 4-chloro-4-deoxy-alpha-D-galactopyranose and 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose units linked by a glycosidic bond.
General Description	Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards. Sucralose is a polar, chlorinated sugar synthesized from saccharose precursor. It is widely used as a sweetener in a number of food and beverage products.
Pharmaceutical Applications	Sucralose is used as a sweetening agent in beverages, foods, and pharmaceutical applications. It has a sweetening power approximately 300–1000 times that of sucrose and has no aftertaste. It has no nutritional value, is noncariogenic, does not promote dental caries, and produces no glycemic response.
Biochem/physiol Actions	A synthetic sweet tastant detectable by humans. Activates T1R2/T1R3 sweet taste receptors on enteroendocrine cells and elicits increased hormonal secretion of glucagon-like peptide-1 and glucose-dependent insulinotrophic peptide.
Safety	Sucralose is generally regarded as a nontoxic and nonirritant material and is approved, in a number of countries, for use in food products. Following oral consumption, sucralose is mainly unabsorbed and is excreted in the feces. The WHO has set an acceptable daily intake for sucralose of up to 15 mg/kg body-weight. LD50 (mouse, oral): > 16 g/kg LD50 (rat, oral): > 10 g/kg

First aid measures

General advice

Consult a physician. Show this material safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

Firefighting measures

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from the substance or mixture

Carbon oxides Nitrogen oxides (NOx)

Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

Environmental precautions

Do not let product enter drains.

Methods and materials for containment and cleaning up

Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

Sucralose

Other Name:

α-D-Galactopyranoside,1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl 4-chloro-4-deoxy-;1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl 4-chloro-4-deoxy-α-D-galactopyranoside;1′,4,6′-Trichlorogalactosucrose;4,1′,6′-Trichloro-4,1′,6′-trideoxygalactosucrose;Sucralose;Splenda;Aspasvit;Sansweet SU 100;TGS;Acucar Light;San Sweet SA 8020;Sucrazit;Sansweet;Predillon SU 600;Sansweet SU 200;1450725-31-1

CAS No.:

56038-13-2

Molecular Formula:

C12H19Cl3O8

InChIKeys:

InChIKey=BAQAVOSOZGMPRM-QBMZZYIRSA-N

Molecular Weight:

397.633

Exact Mass:

397.63

EC Number:

259-952-2

UNII:

96K6UQ3ZD4

NSC Number:

759272

DSSTox ID:

DTXSID1040245

Color/Form:

White to off white, crystalline powder|Anhydrous crystalline form: orthorhombic, needle-like crystals|Syrup

HScode:

2932999099

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

128.84

XLogP3:

-1.5

Appearance:

White crystal powder

Density:

1.375 g/cm

Melting Point:

130 °C

Boiling Point:

104-107 C

Flash Point:

358.7ºC

Refractive Index:

1.604

Water Solubility:

In water, 2.27X10+4 mg/L at 25 deg C (est)

Storage Conditions:

Hygroscopic, -20ºC Freezer, Under Inert Atmosphere

Vapor Pressure:

3.25X10-14 mm Hg at 25 deg C (est)

Toxicity:

LD50 orally in Rabbit: > 10000 mg/kg

Taste:

Intensely sweet taste

Henrys Law Constant:

Henry's Law constant = 3.99X10-19 atm-cu m/mol at 25 °C (est)

Collision Cross Section:

177.2 Å² [M+Na]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|179.16 Å² [M-H]-

Experimental Properties:

Sugar equivalence value relative to sucrose = 600|In water ... stable to heat over a wide range of pH|Hydroxyl radical reaction rate constant = 5.42X10-11 cu cm/molec-sec at 25 °C (est)

See More Sucralose Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Sucralose Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

55 Inquiries

Country	Product	Purchase Quantity	Date Posted
South Korea	Sucralose	500 G	Feb 19, 2025
Tunisia	Sucralose	1.00 MT	Dec 3, 2024
Kenya	Sucralose	1 20' Fcl	Apr 21, 2026
United Kingdom	Sucralose	1 20' Fcl	Mar 20, 2026
Pakistan	Sucralose E955	1 20' Fcl	Feb 3, 2026
Austria	Sucralose	50 MG	Jan 19, 2026
Italy	Sucralose	1 MT	Sep 28, 2025
South Korea	Sucralose	1.00 KG	Sep 16, 2025
China	sucralose	1 MT	Sep 16, 2025
China	sucralose	20 MT	Sep 8, 2025
China	sucralose	1 20' Fcl	Aug 21, 2025
China	sucralose	1 20' Fcl	Aug 19, 2025
Brazil	Sucralose	100 KG	Aug 19, 2025
Panama	SUCRALOSE	1 MT	Aug 13, 2025
China	Sucralose	1 MT	Aug 5, 2025
Pakistan	SUCRALOSE	500.00 KG	Aug 2, 2025
Kenya	Sucralose	1 20' Fcl	Jul 7, 2025
Thailand	sucralose	1 20' Fcl	Jul 2, 2025
Zimbabwe	sucralose	25 KG	May 13, 2025
Kenya	Sucralose	0.1 MT	Mar 20, 2025

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