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Aspartame 22839-47-0 C14H18N2O5

Name: Aspartame 22839-47-0 C14H18N2O5
Brand: Orient
SKU: pr2512121424
Price: 4 USD
Availability: InStock

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CAS No.:

22839-47-0

Grade:

Industrial Grade

Content:

98%

Port:

SHANGHAI

Brand:

Orient

Packaging:

1KG, 25KG, 200KG, 1000KG, customized

Price valid (until):

2026-01-12

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Focusing on innovative research, development, and production in the field of fine chemicals, we prioritize technology, quality, and market orientation. We collaborate with global partners to build a high-tech chemical industry chain and promote sustainable development in the industry.

The company's main products include pharmaceutical intermediates, food additives, essence, spices and plant extracts. The products have passed international certification and are exported to Europe, America, Japan, South Korea and Southeast Asia.

Product Name:	Aspartame
Synonyms:	c-mer;Monoclonal Anti-MERTK antibody produced in mouse;RP38;E962;Asp-Phe-OMe H-Asp-Phe-OMe N-(L-α-Aspartyl)-L-phenylalanine methyl ester N-L-alpha-Aspartyl-L-phenylalanine 1-Methyl Ester L-Aspartyl-L-phenylalanine methyl ester;L-ASPARTYL-L-PHENYLALANINE METHYL ESTER;L-ASP-PHE METHYL ESTER;Asp-Phe-OMe
CAS:	22839-47-0
MF:	C14H18N2O5
MW:	294.31
EINECS:	245-261-3
Product Categories:	FOOD ADDITIVES;Amino Acid Derivatives;Food & Feed ADDITIVES;Biochemistry;Oligopeptides;Peptide Synthesis;Sweeteners;Food & Flavor Additives;Amines;Aromatics;Chiral Reagents;NUTRASWEET;Food additive;Pyridines;Intermediates & Fine Chemicals;Pharmaceuticals;22839-47-0
Mol File:	22839-47-0.mol

Aspartame Chemical Properties

Melting point	242-248 °C
alpha	15.5 º (c=4, 15N formic acid)
Boiling point	436.08°C (rough estimate)
density	1.2051 (rough estimate)
refractive index	14.5 ° (C=4, 15mol/L Formic Acid)
storage temp.	2-8°C
solubility	Sparingly soluble or slightly soluble in water and in ethanol (96 per cent), practically insoluble in hexane and in methylene chloride.
pka	pKa 3.19±0.01 (H2O t=25.0 I=0.100(NaCl))(Approximate);7.87±0.02(H2O t=25.0 I=0.100(NaCl))(Approximate)
form	Powder
color	White
Odor	odorless with a sweet taste
PH	pH(8g/l, 25℃) : 4.5～6.0
biological source	mouse
Water Solubility	Soluble in formic acid, dimethyl sulfoxide. Sparingly soluble in water and ethanol.
Merck	14,839
BRN	2223850
Sequence	H-Asp-Phe-OMe
Stability:	Stable. Incompatible with strong oxidizing agents.
InChIKey	IAOZJIPTCAWIRG-QWRGUYRKSA-N
LogP	0.542 (est)
CAS DataBase Reference	22839-47-0(CAS DataBase Reference)
EPA Substance Registry System	L-Phenylalanine, L-.alpha.-aspartyl-, 2-methyl ester (22839-47-0)

Safety Information

Safety Statements	22-24/25
WGK Germany	2
RTECS	WM3407000
TSCA	Yes
HS Code	29242990
Hazardous Substances Data	22839-47-0(Hazardous Substances Data)
Toxicity	TDLo orl-wmn: 3710 mg/kg:SKN AIMEAS 104,207,86

MSDS Information

Aspartame Usage And Synthesis

Artificial sweeteners	Aspartame is a kind of artificial sweeteners, belongs to the amino acid dipeptide derivatives, by the chemist developed ulcer drugs found in 1965. With low dosage, high sweetness (sweetness is 150 to 200 times of sucrose), good taste, enhance flavor of citrus and other fruits and reducing heat does not produce dental caries, toxicity than saccharin and other synthetic sweetening agent advantages, is widely applied to beverages, diabetic food and some slimming health food, our daily life to drink cola formula once containing the product. Aspartame in the metabolic processes in the body and the main degradation products are phenylalanine, methanol and aspartic acid, does not enter blood circulation, and does not accumulate in the body, food for the health harmless. But due to metabolic defects in patients with phenylketonuria (PKU), excessive body phenylalanine can influence its development, so in patients with the disease to disable adding aspartame.
Neotame	Neotame is aspartate dipeptide derivatives, is a new product developed at a cost of $80 million by American newt company after aspartame, representing the latest achievements of sweetener research field. It is according to the human sweet receptor double hydrophobic binding hypothesis. In aspartame molecule with a hydrophobic groups and the formation of aspartame derivatives. It can also act on the human sweet receptor of two hydrophobic binding sites and therefore sweetness increased greatly, 6000 to 10000 times sweeter than sucrose, 30 to 60 times than Biasiba sweet . It retains many excellent characteristics such as aspartame, pure sweet taste and good flavor enhancing properties distribution, no energy, no caries, stable in acidic medium. Moreover, it is still a lot better than aspartame in dry conditions, it has a longer shelf life; in neutral medium or instantaneous high temperature sterilization conditions, its stability greatly exceed aspartame, which can be used as a sweetener in baking. Neotame can also be used together with reducing sugar and aldehyde flavor without adverse reaction, its safety is better than aspartame and has been greatly improved. Due to its high sweetness, etc. Sweeter is lower than the cost of aspartame. Therefore, neotame has huge market potential. In December of 1998, neotame as food sweeteners status of application have been proposed in the United States, and some other countries for the certification work is in July 9, 2002 . The U. S. Food and Drug Administration (FDA) confirmed the neotame safety and functional type, currently is in March 10, worldwide more regulatory agency and national review in 2003, China's Ministry of Health approval for neotame as a sweetener used in all kinds of food. The above information is edited by the Chemicalbook Han Ya.
Content analysis	Accurately take sample of about 300 mg, moves into a 150ml beaker, dissolve in 96% formic acid 1.5ml, and glacial acetic 60ml. with crystal violet solution (ts-74), with 0.1 mol/L HClO4 immediately titrate to the end of green. At the same time a blank titration and make necessary correction. Each mI.0.1mol/L perchloric acid is the equivalent of 29.43mg C14H18N2O5.

First aid measures

General advice

Consult a physician. Show this material safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

Firefighting measures

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from the substance or mixture

Carbon oxides Nitrogen oxides (NOx)

Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

Aspartame

Other Name:

L-Phenylalanine,L-α-aspartyl-,2-methyl ester;Succinamic acid,3-amino-N-(α-carboxyphenethyl)-,N-methyl ester,stereoisomer;L-Phenylalanine,N-L-α-aspartyl-,1-methyl ester;L-Aspartyl-L-phenylalanine methyl ester;Aspartylphenylalanine methyl ester;L-α-Aspartyl-L-phenylalanine methyl ester;L-Aspartyl-L-3-phenylalanine methyl ester;α-L-Aspartyl-L-phenylalanine methyl ester;Methyl aspartylphenylalanate;Sweet dipeptide;Aspartame;L-Aspartyl-L-phenylalanyl methyl ester;Canderel;Dipeptide sweetener;α-Sweet;NutraSweet;Palsweet Diet;E 951;Pal Sweet;Equal;α-Aspartame;L-Aspartame;Finn;Zero-Cal;Sladex;Pal Sweet Diet G 100;7421-84-3;53906-69-7;172964-81-7

CAS No.:

22839-47-0

Molecular Formula:

C14H18N2O5

InChIKeys:

InChIKey=IAOZJIPTCAWIRG-QWRGUYRKSA-N

Molecular Weight:

294.30300

Exact Mass:

294.30

EC Number:

616-062-2

UNII:

Z0H242BBR1

NSC Number:

758953

DSSTox ID:

DTXSID0020107

Color/Form:

Colorless needles from water|White crystalline powder from water or alcohol

HScode:

2924299090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

118.72000

XLogP3:

-2.7

Appearance:

White powder or flake

Density:

1.28 g/cm3

Melting Point:

246-247 °C

Boiling Point:

535.8ºC at 760 mmHg

Flash Point:

277.8ºC

Refractive Index:

14.5 ° (C=4, 15mol/L Formic Acid)

Water Solubility:

The solubility of aspartame in water is dependent on pH and temperature, the maximum solubility is reached at pH 2.2 (20 mg/mL at 25 °C) and the minimum solubility at pH 5.2 (pHi) is 13.5 mg/mL at 25 °C.

Storage Conditions:

Ventilated low temperature drying

Vapor Pressure:

2.6E-12mmHg at 25°C

Toxicity:

TDLo orl-wmn: 3710 mg/kg:SKN AIMEAS 104,207,86

Specific rotation:

[α]D/20: + 14,5° to + 16,5°; Determine in a 4 in 100/15 N formic acid solution within 30 minutes after preparation of the sample solution

Odor:

Odorless

Taste:

Sweet

PH:

Between 4,5 and 6,0 (1 in 125 solution)

Henrys Law Constant:

Henry's Law constant = 2.53X10-18 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

pKa1 = 2.96 (carboxyl); pKa2 = 7.30 (amine) (est)

Collision Cross Section:

169.6 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|166.71 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|167.6 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|126.6 Å² [M-H]-

Experimental Properties:

Dipeptide ester about 160 times sweeter than sucrose in aqueous solution

See More Aspartame Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

The bulk material should be stored in a well-closed container, in a cool, dry place.

See More Aspartame Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

42 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Aspartame factory price 99% White powder 22839-47-0 ShandongDeShang	2 MT	Oct 7, 2023
Canada	Aspartame	3 20' Fcl	Mar 15, 2024
United Kingdom	Aspartame	6 20' Fcl	Jul 16, 2024
United Kingdom	Aspartame	2 20' Fcl	Aug 1, 2024
United Kingdom	Aspartame	40 MT	Aug 1, 2024
Bangladesh	Aspartame BP	500 KG	Nov 26, 2023
Bangladesh	Aspartame	500 KG	Nov 27, 2023
Portugal	Aspartame	100 MT	Feb 7, 2025
Portugal	Aspartame	100 MT	Mar 5, 2025
United Arab Emirates	Aspartame	300 MT	Mar 27, 2026
United Arab Emirates	Aspartame	300 MT	Apr 8, 2026
United States	Aspartame	18 MT	May 25, 2026
Bangladesh	Aspartame	5 MT	Mar 20, 2026
India	Aspartame	1000 KG	Jun 4, 2025
Japan	aspartame	88 MT	Feb 27, 2025
Chile	Aspartame	500 KG	Nov 14, 2024
India	Aspartame G Sweet	50.00 KG	Nov 5, 2024
United States	Aspartame	1 MT	Jul 17, 2024
Bangladesh	Aspartame	2 MT	Jun 27, 2024
South Africa	Aspartame	1 20' Fcl	Mar 13, 2024

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