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Methyl thioglycolate 2365-48-2 MTG

Name: Methyl thioglycolate 2365-48-2 MTG
Brand: Orient
SKU: pr2512161557
Price: 4 USD
Availability: InStock

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CAS No.:

2365-48-2

Grade:

Industrail Grade

Content:

99%

Port:

SHANGHAI

Brand:

Orient

Packaging:

25L, 200L, 1000L, customized

Price valid (until):

2026-01-16

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Name:	Methyl thioglycolate
Synonyms:	MERCAPTOACETIC ACID METHYL ESTER;METG;METHYL THIOGLYCOLATE;METHYL THIOGLYCOLLATE;METHYL MERCAPTOACETATE;THIOGLYCOLIC ACID METHYL ESTER;mercapto-aceticacimethylester;Methanethiol, methoxy-
CAS:	2365-48-2
MF:	C3H6O2S
MW:	106.14
EINECS:	219-121-7
Product Categories:	2365-48-2
Mol File:	2365-48-2.mol

Methyl thioglycolate Chemical Properties

Melting point	-24 °C
Boiling point	42-43 °C/10 mmHg (lit.)
density	1.187 g/mL at 25 °C (lit.)
refractive index	n20/D 1.466(lit.)
Fp	86 °F
storage temp.	Store below +30°C.
solubility	40g/l
pka	8.04±0.10(Predicted)
form	Liquid
color	Clear colorless
Odor	Strong, unpleasant, garlic-like
Water Solubility	40 g/L (20 ºC)
Sensitive	Air Sensitive
BRN	506259
InChIKey	MKIJJIMOAABWGF-UHFFFAOYSA-N
CAS DataBase Reference	2365-48-2(CAS DataBase Reference)
NIST Chemistry Reference	Acetic acid, mercapto-, methyl ester(2365-48-2)
EPA Substance Registry System	Acetic acid, mercapto-, methyl ester (2365-48-2)

Safety Information

Hazard Codes	Xn,T
Risk Statements	10-20/22-36/37/38-25
Safety Statements	26-36/37-45-36/37/39-28A
RIDADR	UN 1992 3/PG 3
WGK Germany	1
RTECS	AI7350000
TSCA	Yes
HazardClass	3
PackingGroup	III
HS Code	29309070
Hazardous Substances Data	2365-48-2(Hazardous Substances Data)
Toxicity	mouse,LD50,intraperitoneal,100mg/kg (100mg/kg),National Technical Information Service. Vol. AD277-689,

MSDS Information

Methyl thioglycolate Usage And Synthesis

Chemical Properties	CLEAR COLOURLESS LIQUID
Uses	Methyl Thioglycolate is an derivative of Thioglycolic Acid (T350760), an organic compound containing both a thiol and a carboxylic acid functional groups. Thioglycolic Acid and its derivatives are oft en used in organic synthesis as a nucleophile in thioglycolysis reactions and is also used as a S transfer agent for sulfonyl chloride synthesis. Methyl Thioglycolate have been studied for the its inf luence on neocarzinostatin activation and expression of DNA damage.
Uses	Methyl thioglycolate was used in the preparation of 3-carbomethoxy-4- oxotetrahydrothiopyran, 2- and 4-carbomethoxy-3-oxotetrahydrothiophene. It is used to prepare methyl thioglycolate and aminoethanethiol conjugated gold nanorods.
Application	Methyl thioglycolate is a chemical compound that is used in the pharmaceutical industry as an intermediate. It has been used to synthesize anti-inflammatory drugs, such as aspirin and ibuprofen, and also for the treatment of autoimmune diseases. Methyl thioglycolate binds to amino acids on the surface of bacteria, which prevents them from functioning properly. This binding causes the cells to stop growing and die.
Definition	Methyl thioglycolate are widely used in free-radical photoinitiated polymerization reactions. In particular, the use of methyl thioglycolate (MTG), CH3OC(O)CH2SH, results in greater photopolymerization reaction rates, attributed to a weakening of the sulfur–hydrogen bond by hydrogen bonding of the thiol group. MTG constitutes the smaller exponent of the series of CH3OC(O)(CH2)nSH compounds, reported as intermediated in the organic sulfur cycle in marine environments, produced by marine phytoplankton.
Production Methods	Adding thioglycollic acid with purity of between 70.0 and 96.0 percent and methanol with purity of between 95.0 and 99.9 percent into a reaction device according to the molar ratio of 1:1.3-4.0; subsequently, adding an activating agent into the reaction device, stirring and heating for reaction; and after the reaction is finished, carrying out separatory distillation on reaction products to obtain the methyl thioglycolate. The activating agent is a p-toluenesulfonic acid methanol solution with a mass concentration of between 20 and 30 percent, and the use amount is 0.5 to 1.0 percent of the total mass of relative input materials.

First aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak. Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

Methyl thioglycolate

Other Name:

Acetic acid,2-mercapto-,methyl ester;Acetic acid,mercapto-,methyl ester;Methyl mercaptoacetate;Methyl thioglycolate;Thioglycolic acid methyl ester;Methyl 2-mercaptoacetate;Mercaptoacetic acid methyl ester;Methyl α-mercaptoacetate;NSC 75117;2-Mercaptoacetic acid methyl ester;Methyl sulfanylacetate;Methyl 2-sulfanylacetate;64807-90-5;1629585-98-3

CAS No.:

2365-48-2

Molecular Formula:

C3H6O2S

InChIKeys:

InChIKey=MKIJJIMOAABWGF-UHFFFAOYSA-N

Molecular Weight:

106.14400

Exact Mass:

106.14

EC Number:

219-121-7

UNII:

O1608LA9EL

NSC Number:

75117

DSSTox ID:

DTXSID0033673

HScode:

29309070

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

65.10000

XLogP3:

0.08920

Density:

1.187

Melting Point:

-24ºC

Boiling Point:

148 °C

Flash Point:

56ºC

Refractive Index:

1.464-1.467

Water Solubility:

H2O: 40 g/L (20 ºC)

Storage Conditions:

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool

Vapor Pressure:

3.58mmHg at 25°C

Dissociation Constants:

pKa= 8.08 @ 25 °C

See More Methyl thioglycolate Properties 

Hazard Identification

Classification of the substance or mixture

Flammable liquids, Category 3

Acute toxicity - Category 3, Oral

Skin irritation, Category 2

Eye irritation, Category 2

Acute toxicity - Category 4, Inhalation

Specific target organ toxicity â single exposure, Category 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H226 Flammable liquid and vapour H301 Toxic if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H332 Harmful if inhaled H335 May cause respiratory irritation
Prevention	P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 Keep container tightly closed. P240 Ground and bond container and receiving equipment. P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment. P242 Use non-sparking tools. P243 Take action to prevent static discharges. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower]. P370+P378 In case of fire: Use ... to extinguish. P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P317 Get medical help. P319 Get medical help if you feel unwell.
Storage	P403+P235 Store in a well-ventilated place. Keep cool. P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Methyl thioglycolate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
United Kingdom	Methyl thio glycolate	11 KG	Apr 27, 2026

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