China factory Best quality High Purity 99% Peptide Retatrutide 20mg + Trizepatide 40mg (10ml) weight loss

Mechanism of Action and Molecular Structure of Retatrutide:

Triple Agonist Design
- GLP-1 receptor: Retatrutide delays gastric emptying, suppress appetite, and promote insulin secretion.
- GIP receptor: Retatrutide enhances insulin sensitivity and regulate central satiety signals.
- Glucagon receptor (GCGR): Retatrutide activates liver energy metabolism, promote lipolysis and glycogenolysis, and increase basal metabolic rate.
The triple synergistic effect increases energy consumption while reducing energy intake, significantly improving weight loss effects.

Indications and Efficacy:

★ Obesity Treatment:
In the Phase II clinical trial, patients in the highest dose group (12 mg) lost an average of 24.2% weight after 48 weeks, and some patients lost more than 30%.

★ Metabolic Dysfunction-Associated Fatty Liver Disease (MASLD):
Retatrutide can reduce liver fat content by 86%, and more than 85% of patients achieve regression of liver steatosis.

★ Type 2 Diabetes:
Significantly reduce glycated hemoglobin (HbA1c) and improve blood sugar control.

★ Potential Cardiovascular Benefits:
Animal studies have shown that it may indirectly protect cardiovascular health by improving blood pressure and heart function, but further clinical verification is needed.

Before and after weight loss：

• Products Application
• 1.Helps slow food leaving your stomach
• 2.Helps prevent your liver from making too much  sugar
• 3.Helps the pancreas produce more insul when your blood sugar levels are high
• 4.Can help control  blood glucose
• 5.Can reduce hyperglycemia, especially after meals
• 6.Can reduce fasting insul and fasting glucose
• 7.Can reduce  hemoglobin A1c
• 8.Can  decrease appetite and caloric intake, while inhibiting weight gain
• 9.Has been shown to lower triglyceride levels and oxidative stress from high LDL

Clinical Effects and Core Data of Retatrutide:、

1) Outstanding Weight Loss Effect:
- 48 weeks of treatment: The average weight loss in the 12mg dose group reached 24.2%, significantly better than existing drugs (such as Semaglutide and Tirzepatide).
- Gender differences: Women have a more significant weight loss effect (28.5% vs. men 21.2%).
- Dose dependence: From the starting dose of 2mg to 12mg, the weight loss ratio increases with the dose.

Comparison of Weight Loss Effects at Different Doses (48-Week Data):

2) Comprehensive Improvement of Metabolism:

- Blood sugar control: Significantly reduce glycated hemoglobin (HbA1c), and doses above 4mg are better than dulaglutide.
- Cardiovascular metabolism: Improve triglyceride, cholesterol and blood pressure levels, potentially reducing cardiovascular risks.
- Expanded indications: Used in research for metabolic-related diseases such as polycystic ovary syndrome (PCOS).