 Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > N-Bromosuccinimide for Sale > N-Bromosuccinimide CAS:128-08-5 NBS

N-Bromosuccinimide CAS:128-08-5 NBS buy - large image1

N-Bromosuccinimide CAS:128-08-5 NBS buy - image1

N-Bromosuccinimide CAS:128-08-5 NBS buy - image2

N-Bromosuccinimide CAS:128-08-5 NBS buy - image3

N-Bromosuccinimide CAS:128-08-5 NBS buy - image4

N-Bromosuccinimide CAS:128-08-5 NBS

Name: N-Bromosuccinimide CAS:128-08-5 NBS
Brand: Orient
SKU: pr2512292312
Price: 4 USD
Availability: InStock

TDS 4 Inquiries

Unit Price: Get Latest Price 

CAS No.:

128-08-5

Grade:

Industrail Grade

Content:

99%

Port:

SHANGHAI

Brand:

Orient

Packaging:

1KG, 5KG, 25KG

Price valid (until):

2026-01-29

Contact Supplier

 Chat Now

Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Product Name:	N-Bromosuccinimide
Synonyms:	2,5-PYRROLIDINEDIONE, 1-BROMO-;1-BROMO-2,5-PYRROLIDINEDIONE;N-BROMOSUCCINIMIDE;N-BROMOSUCINIMIDE;NBS;N-BROMOBUTANIMIDE;bromosuccinimide;BROMOSUCCINIMIDE-N
CAS:	128-08-5
MF:	C4H4BrNO2
MW:	177.98
EINECS:	204-877-2
Product Categories:	Medical Intermediates;Nitrogen cyclic compounds;Biochemistry;Bromination;Halogenation;N-Substituted Maleimides, Succinimides & Phthalimides;N-Substituted Succinimides;Reagents for Oligosaccharide Synthesis;Synthetic Organic Chemistry;128-08-5
Mol File:	128-08-5.mol

N-Bromosuccinimide Chemical Properties

Melting point	175-180 °C (dec.)(lit.)
Boiling point	221.4°C (rough estimate)
bulk density	750kg/m3
density	2.098
vapor pressure	14.8 hPa (20 °C)
refractive index	1.6060 (estimate)
storage temp.	Store at +2°C to +8°C.
solubility	14.8g/l (decomposition)
pka	-2.78±0.20(Predicted)
form	Crystalline Powder
color	White to light yellow
Odor	characteristic odour of bromine
biological source	rabbit
Water Solubility	Soluble in acetone, tetrahydrofuran, dimethyl formamide, dimethyl sulfoxide and acetonitrile. Slightly soluble in water and acetic acid. Insoluble in ether, hexane and carbon tetrachloride.
Sensitive	Moisture Sensitive
Merck	14,1438
BRN	113916
Stability:	Stable. Incompatible with strong oxidizing agents, halogenated hydrocarbons.
InChIKey	PCLIMKBDDGJMGD-UHFFFAOYSA-N
LogP	-1.19
CAS DataBase Reference	128-08-5(CAS DataBase Reference)
NIST Chemistry Reference	2,5-Pyrrolidinedione, 1-bromo-(128-08-5)
EPA Substance Registry System	N-Bromosuccinimide (128-08-5)

Safety Information

Hazard Codes	C,Xn
Risk Statements	22-34-36/37/38
Safety Statements	26-36/37/39-45-37/39
RIDADR	UN 3261 8/PG 2
WGK Germany	3
Hazard Note	Harmful
TSCA	Yes
HazardClass	8
PackingGroup	III
HS Code	29251995
Hazardous Substances Data	128-08-5(Hazardous Substances Data)
Toxicity	LD50 orally in Rabbit: > 2000 mg/kg

MSDS Information

N-Bromosuccinimide Usage And Synthesis

Chemical Properties	white to light yellow crystalline powder
Uses	N-Bromosuccinimide is a brominated succinimide used as a chemical reagent in radical substitution and electrophilic addition reactions in organic synthesis. In bromination of olefins; in oxidation of alcohols to aldehydes and ketones and of aldehydes to acid bromides.
Definition	ChEBI: N-bromosuccinimide is a five-membered cyclic dicarboximide compound having a bromo substituent on the nitrogen atom. It has a role as a reagent. It is a dicarboximide, a pyrrolidinone and an organobromine compound. It is functionally related to a succinimide.
Preparation	N-Bromosuccinimide is prepared by addition of bromine to a cold aqueous solution of succinimide or by reaction of succinimide with NaBrO2 in the presence of HBr. 1.62mol (160g) succinimide is dissolved in a mixture of 1.60mol (64g) NaOH, 300g crushed ice and 400ml water. Cool the mixture in an ice bath, and add 85ml (1.65 mol, 264g) Br2 at once while stirring violently. Stir for two more minutes, then filter the precipitated product and wash with ice water. Dry in a desiccator. Yield 75-81%. Don't clean up NBS too much, the stinky yellow stuff still containing a bit of Br2 works best. N-Bromosuccinimide is a brominating agent that replaces hydrogen atoms in benzylic or allylic positions. It is used in the oxidation of secondary alcohols to ketones and in controlled low-energy brominations.
Flammability and Explosibility	Non flammable
reaction suitability	reagent type: oxidant
Safety Profile	Poison by intraperitoneal route. An irritating poison to skin, eyes, and mucous membranes. Reacts explosively with adme, dtallyl sulfide, and hydrazine hydrate. Explosive reaction with propiononitrile after heating to 105℃ for 24 hours. Violent reaction with dtbenzoyl peroxide + 4-tok acid. When heated to decomposition it emits toxic fumes of Brand NOx. See also BROMIDES and NITROGEN MONOXIDE.
Purification Methods	N-Bromosuccinimide (30g) is purified by dissolving rapidly in 300mL of boiling water and filtering through a fluted filter paper into a flask immersed in an ice bath, and left for 2hours. The crystals are filtered off, washed thoroughly with ca 100mL of ice-cold water and drained on a Büchner funnel before drying under vacuun over P2O5 or CaCl2 [Dauben & McCoy J Am Chem Soc 81 4863 1959]. This brominating agent has also been crystallised from acetic acid or water (10 parts), washed in water and dried in vacuo [Wilcox et al. J Am Chem Soc 108 7693 1986, Shell et al. J Am Chem Soc 108 121 1986, Phillips & Cohen J Am Chem Soc 108 2013 1986, Beilstein 21/9 V 543.]

First aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak. Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

Firefighting measures

Extinguishing media

Use dry chemical, carbon dioxide or alcohol-resistant foam.

Specific Hazards Arising from the Chemical

no data available

Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.

Shop Orthophosphorus acid 10294-56-1-Detailed Image 1

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 2

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 3

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 4

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 5

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 6

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 7

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 8

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 9

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 10

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 11

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 12

—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

N-Bromosuccinimide

Other Name:

2,5-Pyrrolidinedione,1-bromo-;Succinimide,N-bromo-;1-Bromo-2,5-pyrrolidinedione;N-Bromosuccinimide;NBS;Succinbromimide;Bromosuccinimide;NSC 16;N-Bromobutanimide;133435-75-3;3493-39-8

CAS No.:

128-08-5

Molecular Formula:

C4H4BrNO2

InChIKeys:

InChIKey=PCLIMKBDDGJMGD-UHFFFAOYSA-N

Molecular Weight:

177.98

Exact Mass:

177.98

BRN:

113916

EC Number:

204-877-2

UNII:

K8G1F2UCJF

NSC Number:

DSSTox ID:

DTXSID2038738

Color/Form:

Orthorhombic bisphenoidal crystals|Crystals from benzene|Solid at 20 °C and 1031 hPa; powder

HScode:

29251995

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

37.4

XLogP3:

-0.1

Appearance:

White to light yellow Crystalline Powder

Density:

2.098 g/cu cm at 25 deg C

Melting Point:

174 °C

Boiling Point:

338.9 deg C at 101.325 kPa

Flash Point:

87.7±22.6 °C

Refractive Index:

1.6060 (estimate)

Water Solubility:

soluble in acetone, tetrahydrofuran, dimethyl formamide, dimethyl sulfoxide and acetonitrile. Slightly soluble in water and acetic acid. Insoluble in ether, hexane and carbon tetrachloride.

Storage Conditions:

0-6°C

Vapor Pressure:

14.8 hPa (20 °C)

Toxicity:

Abdominal cavity-mouse LDL0: 256 mg/kg

Flammability characteristics:

Irritating to human eyes, skin and mucous membranes; thermal decomposition decomposes toxic nitrogen oxides and bromide fumes

Odor:

Faint odor of bromine

Henrys Law Constant:

Henry's Law constant = 3.87X10-7 atm-cu m/mol at 25 °C (est)

Experimental Properties:

Hydroxyl radical reaction rate constant = 1.85X10-11 cu cm/molec-sec at 25 °C (est)

See More N-Bromosuccinimide Properties 

Hazard Identification

Classification of the substance or mixture

Corrosive to metals, Category 1

Skin irritation, Category 2

Eye irritation, Category 2

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H272 May intensify fire; oxidizer H290 May be corrosive to metals H315 Causes skin irritation H319 Causes serious eye irritation H400 Very toxic to aquatic life
Prevention	P234 Keep only in original packaging. P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P273 Avoid release to the environment.
Response	P390 Absorb spillage to prevent material damage. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P391 Collect spillage.
Storage	P406 Store in a corrosion resistant/...container with a resistant inner liner.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More N-Bromosuccinimide Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

4 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	N-Bromosuccinimide	1 MT	Sep 11, 2024
India	N Bromosuccinimide	100 KG	Feb 22, 2024
India	N-Bromosuccinimide	1000 KG	Mar 6, 2025
India	N-bromossuccinamide	100 G	Nov 22, 2024

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
China Most Professional Factory Supply High Qulity N-Bromosuccinimide CAS 128-08-5	Pharmaceutical Grade/99		LEADER BIOCHEMICAL GROUP	Inquiry
N-Bromosuccinimide	Different Grade/99.9	$0.1/KG EXW	Amitychem	Inquiry
128-08-5	/		Guangzhou Yaoguang Technology Co., Ltd.	Inquiry
N-Bromosuccinimide liquid	/		Shandong zhishang chemical Co.,Ltd	Inquiry
N-Bromosuccinimide 99.5% White solid Yuanjinchem	Industrial Grade/99.5		Zhejiang Yuanjin Chemical Co., Ltd.	Inquiry

Hot Related Products



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.