Top Quality AHK-CU

Name:  Lynn
Wechat：  15914422644

Tel：+86  15914422644

Whatsapp: +852 6252 8290

Email：    guangsheng 5   @zgguangsheng.com

1. Molecular & Physical Properties

• Amino Acid Sequence: Ala-His-Lys-Cu, formed by chelating the tripeptide alanyl-histidyl-lysine with copper ions.
• Purity: ≥99% (HPLC verified), ensuring high bioactivity and minimal impurities.
• Physical Appearance: Deep blue lyophilized powder, highly water-soluble for easy formulation into solutions, creams, or injectables.
• Stability: Optimal storage at -20℃; stable for 24 months when sealed from light and moisture; avoid high temperatures to prevent copper ion dissociation.

2. Core Biological Mechanisms

• Collagen & Elastin Synthesis: It upregulates the expression of TGF-β and matrix metalloproteinase inhibitors (TIMPs), stimulating fibroblasts to produce type I/III collagen and elastin. This enhances skin elasticity, reduces fine lines, and improves skin texture.
• Antioxidant & Anti-inflammatory Effects: The copper ion moiety scavenges free radicals (e.g., superoxide anion, hydroxyl radicals) to mitigate oxidative stress. It also inhibits NF-κB pathways, reducing the release of pro-inflammatory cytokines (TNF-α, IL-6) and alleviating tissue inflammation.
• Hair Follicle Activation: It extends the anagen (growth) phase of hair follicles, increases dermal papilla cell proliferation, and improves microcirculation around hair follicles, which aids in reversing hair miniaturization associated with androgenetic alopecia.
• Wound Healing Acceleration: By promoting angiogenesis and fibroblast migration, it speeds up granulation tissue formation and epithelialization, shortening recovery time for acute and chronic wounds (e.g., burns, diabetic ulcers).

3. Application Scenarios

• Dermatological Cosmetics: Added to anti-aging serums, creams, and masks to improve skin firmness, fade wrinkles, and repair photodamaged skin.
• Trichological Research: Used in topical formulations or scalp injections for androgenetic alopecia treatment and hair regrowth studies.
• Regenerative Medicine: Applied in wound care dressings and tissue engineering scaffolds to enhance skin and soft tissue repair.
• Laboratory Research: Serves as a tool compound for studying copper peptide biology, oxidative stress, and tissue regeneration mechanisms.

4. Safety & Advantages

• Non-immunogenic, with no reported allergic reactions or systemic side effects in topical use.
• Biodegradable, breaking down into natural amino acids and copper ions that are metabolized by the body.
• Compatible with most cosmetic and pharmaceutical excipients (e.g., hyaluronic acid, glycerin), suitable for multi-component formulations.