Cagrilintide High quality Weight Loss Peptides 10mg with 99% white Powder in Factory supply wholesale price CAS 1415456-99-3

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• Functions:                                                               
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• Cagrilintide (also known as AM833) is a long‑acting, dual amylin‑calcitonin receptor agonist (DACRA) developed for the treatment of obesity and type 2 diabetes. It functions by mimicking and enhancing the actions of the natural hormone amylin, with additional activity at calcitonin receptors.

1. Central Nervous System (CNS) Effects (Appetite & Satiety)

Suppresses Appetite: Activates receptors in the area postrema and nucleus tractus solitarius in the brainstem, signaling reduced hunger.
Enhances Satiety: Acts on the hypothalamus to increase feelings of fullness, reducing food intake and cravings.
Modulates Reward Pathways: May reduce hedonic eating (eating for pleasure)

2. Gastrointestinal (GI) Effects

Delays Gastric Emptying: Slows the movement of food from the stomach to the intestines, prolonging post‑meal fullness and reducing meal size.
Reduces Gastric Acid Secretion: May improve digestive comfort.

3. Metabolic & Glucose Regulation

Suppresses Glucagon Secretion: Lowers blood glucose by reducing the liver’s glucose output, especially between meals.
Improves Insulin Sensitivity: Aids in better blood sugar control.
Promotes Energy Expenditure: May increase metabolic rate and fat oxidation.

4. Body Weight Regulation

Induces Significant Weight Loss: Clinical trials show ~10–12% weight reduction as monotherapy.
Preserves Lean Body Mass: Compared to some other weight‑loss drugs, it may better maintain muscle mass while reducing fat.
Synergistic with GLP‑1 Agonists: When combined with semaglutide, it produces greater weight loss (often >15%) than either drug alone, with potentially fewer GI side effectsPubMed

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  Lyophilization Technology Advantages:                
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  Our Cagrilintide undergoes state-of-the-art freeze-drying process that delivers unmatched benefits:

  1、Maximum Activity Retention: Preserves Cagrilintide's native structure and biological activity by avoiding thermal degradation

  2、 Exceptional Stability: Extends shelf life to 24 months when stored properly (vs. 3-6 months for liquid forms)

  • 3、Enhanced Purity: Removes residual solvents and moisture completely, minimizing degradation factors
  • 4、Easy Reconstitution: Dissolves rapidly in sterile water or saline with no clumping
  • 5、Reduced Contamination Risk: Aseptic manufacturing process ensures product safety

  
  
  

• Basic Information:                                                   

• Item	Information
  Product Name	Cagrilintide
  CAS No.	1415456-99-3
  Molecular Formula	C₁₉₄H₃₁₂N₅₄O₅₉S₂
  Molecular Weight	4409.01 g/mol
  Product Type	Long‑chain acylated amylin analogue; dual agonist of amylin receptor (AMYR) and calcitonin receptor (CTR)
  Appearance	White powder
  Mechanism of Action	1. Activates amylin receptors: suppresses appetite, delays gastric emptying, reduces food intake 2. Activates calcitonin receptors: enhances satiety and synergistic weight loss 3. N‑terminal fatty acid modification for significantly prolonged half-life
  Main Clinical Applications	1. Obesity: Phase 2 clinical data – 4.5 mg/week, approximately 10.8% weight loss in 26 weeks 2. Type 2 diabetes: assists glycemic control and improves insulin sensitivity

  
  

Company Profile：                                                 

LingMi BioTechnology Co., Ltd is a modern advanced enterprise specializing in production and exportation of APIs, Pharmaceutical intermediates, plant extracts etc. Our products are widely used in medicine, health care products, cosmetics, nutritional supplements and food additives areas. With years of experience in the pharmaceutical chemical and biosynthetic industries.It provides compliant, stable and cost-effective core raw materials as well as one-stop CDMO/CMO solutions for global pharmaceutical enterprises and innovative drug R&D institutions.